Jacob Weber Email & Phone Number

New York, NY, US

Sydney, NSW, AU

Hiked the Pacific Crest Trail, a 2650 mile (4265 km) backpacking journey from Mexico to Canada through the mountains of California, Oregon, and Washington

Tarrytown, New York, US

Process Development o Developed 5 commercial bioreactor processes using Quality by Design and Design of Experiment principles to optimize production of monoclonal antibodies and ensure robust quality attributes.o Led internal technology transfer of 2 commercial bioreactor processes to GMP manufacturing environment (2000L scale).o Design and execute.

Tarrytown, New York, US

Tarrytown, New York, US

San Francisco, CA, US

Participated in a twelve-week cohort-based program designed to cultivate collaboration and connectivity among climate professionals, startup founders, scientists, engineers, designers, investors, and subject-matter experts.

Cambridge, MA, US

Performed technology diligence and analysis on precision fermentation, food technology, and climate technology start ups for venture capital firms and institutional investors.

Set up and operation of 7L Applikon bioreactor for fermentation of engineered yeast (Pichia pastoris) strains to produce mutant alpha-galactosidase for enzyme replacement therapy research.Separation and purification of enzyme using tangential flow filtration and diafiltration.Perform enzyme assays and create substrate saturation curves to determine enzyme.

Ludwigshafen, DE

Overhauled site process information management system (PIMS) to streamline data management and visualization across research, pilot, and manufacturing scales.Collaborated with fermentation scientists to refine MS Excel dashboards for offline data upload and interfaced with engineers and operators to integrate the process into their workflow.Conducted.

Ludwigshafen, DE

Engineering and fermentation of industrial host strain for enzyme production.Performed and troubleshot bacterial transformations, PCR experiments, DNA gel electrophoresis, media optimization studies, and enzyme assays.Set up and operated lab scale bioreactors from one to five-liter reactor volumes.Collaborated with international scientists and engineers on.

Synthesize polypeptides using Fmoc solid-phase peptide synthesis. Analyze secondary structure with circular dichroism. Perform microrheology to study peptide self-assembly kinetics.Utilize ImageJ and Matlab to calculate material properties of resulting peptide hydrogel. Selected Publication: S. C. O’Neill, A. D. Kanthe, J. A. Weber and R. S. Tu, “.

Franklin Lakes, New Jersey, US

Performed mechanical testing including tension, compression, and torsion measurements on BD products using Instron Testing machines.Collected and analyzed data with Microsoft Excel and Minitab, and reported results to R&D management and peers with spreadsheets, presentations, and technical reports.Collaborated with lab technicians, engineers, and marketing.

Trained and assisted structural design consultants in Autodesk Inventor software.Organized and facilitated drawing and spreadsheetuse for structural design consultants.