Jacob Circelli Email & Phone Number

Bellerica, Ma

Marlborough, Massachusetts, United States

• Design and perform experiments to optimize and troubleshoot multiplexed immunofluorescent assays.• Lead multiple projects/studies, generated SOPs and validation documents, and construct timelines for said projects.• Organized and head accelerated and real time stability studies to determine shelf life for antibodies. • Performed various tests on oligo-conjugated antibodies using SDS-PAGE and ELISAs.• Extensively run DAB on human FFPE tissue and have worked alongside pathologists to interpret and evaluate marker specificity.• Created posters and presented for anticipated product launches at AACR and SITC conferences.

Clinton, New York

• Investigated Tetrahymena thermophila’s ability to digest nucleic acids by using nucleoside/base analogs to inhibit growth.• Managed cell cultures measured cell density via absorbance and created growth curves and worked to generate mutant cell lines with the ability to ingest nucleoside analogs.• Worked on targeted cancer therapy using magnetic nanoparticles and alternating magnetic fields to kill human cancer cells (in vitro). Efficacy was measured via MTT assay.

Clinton, New York

Assisted in making solutions for Biochemistry labs as well as grading exams and quizzes.

Hsinchu County/City, Taiwan

Achieved proficiency in various lab techniques and applied said knowledge to determine the efficacy of hyperthermia cancer treatment.Edited manuscripts slated for publication on alternative cancer treatments.