Jake Bowden Email & Phone Number

London, Gb

London, England, United Kingdom

Lead bioinformatics and machine learning innovator at a seed-stage startup. - Integral member of a team which raised £1M in seed funding, completed two commercial contracts and was awarded several R&D grants.- Designed novel nuclease gene editors using generative AI.- Developed an ML system for prediction of secreted heterologous protein yield with R2 >0.55- Contributed to the design of critical wet lab workflows including high-throughput gene editing, quantification of… Show more Lead bioinformatics and machine learning innovator at a seed-stage startup. - Integral member of a team which raised £1M in seed funding, completed two commercial contracts and was awarded several R&D grants.- Designed novel nuclease gene editors using generative AI.- Developed an ML system for prediction of secreted heterologous protein yield with R2 >0.55- Contributed to the design of critical wet lab workflows including high-throughput gene editing, quantification of protein yield and Nanopore-based barcode sequencing.- Co-supervised six MSc students developing applications using the HyenaDNA LLM and a summer intern predicting gene expression level from DNA sequence.- Productionised model training, deployment and inference on AWS. Show less

London, England, United Kingdom

Cambridge, England, United Kingdom

Responsible for entry and validation of hard copy crystallographic data. Implemented automated character correction into the OCR workflow of this task, adding over 500 structures to the Cambridge Structural Database.

Manchester, England, United Kingdom

Research placement in the Barran Group, Manchester Institute of Biotechnology. Development of a undergraduate Lab experiment using Ion-mobility Mass-spectrometry.

Lode, England, United Kingdom

Newmarket, England, United Kingdom

Master'S Degree, Systems & Synthetic Biology, Distinction

MRes as part of the CDT BioDesign Engineering program. Project on refactoring a Type II Polyketide synthase (PKS) pathway in E. coli.

Mchem, Chemistry With Medicinal Chemistry, Upper Second Class (Hons)

MChem Thesis Title: In silico Design of Small Molecule Integrin A11B1 Inhibitors as Potential Anti-Cancer Therapeutics. Third Year.