James Eaglesham Email & Phone Number

Ipswich, MA, US

Ipswich, Massachusetts, United States

I run a small laboratory group dedicated to discovery and mechanistic characterization of phage defense systems. See our lab webpage: https://www.neb.com/research-labs/eaglesham-lab

Ipswich, Massachusetts, United States

Mehmet Berkmen Lab:- Development of a bacterial genetic selection for identification of protein binders- Advised students, postdocs, and summer interns

Boston, Massachusetts

Philip Kranzusch Laboratory - Harvard Medical School/Dana-Farber Cancer InstituteMethods: X-ray crystallography, protein expression, biochemistry, enzyme kinetics, isothermal titration calorimetry, vaccinia molecular virology, mammalian cell culture - Discovered poxins, a new family of 2′3′ cGAMP nucleases which antagonize cGAS/STING immunity. First-author.

Cambridge, United Kingdom

Ian Goodfellow Laboratory, Division of Virology, Department of PathologyMethods: SILAC Proteomics, molecular virology, confocal microscopy- Identified human and viral protein binding partners of two Murine Norovirus proteins. Middle-author on papers published in McCune et al., 2017 (mBio), Hosmillo et al., 2019 (eLife).Recipient of Churchill Scholarship.

Ithaca, New York

John Parker Laboratory, Department of Microbiology and ImmunologyMethods: Molecular virology, ribosome profiling, mammalian cell culture- Utilized ribosome profiling to examine changes to the human lung epithelial cell translatome during infection with mammalian orthoreovirus- Analyzed the role of viperin in the host innate immune response to mammalian.

Bethesda, Maryland

Deborah Hinton Laboratory, Laboratory of Cell and Molecular Biology, NIDDKMethods: Protein biochemistry, protein purification- Purified photocrosslinkable amino acid insertion mutants of a Bordetella pertussis global virulence gene regulator in order to map its interaction with RNA polymerase.

Ithaca, New York

Ian Hewson Laboratory, Department of MicrobiologyMethods: qPCR, DNA metagenome library construction from aquatic organisms- Surveyed circovirus genotypes in zooplankton samples from the Gulf of Maine to the Amazon River Bason, first-author paper published in Marine Ecology Progress Series (2013). - Purified virions from mollusk, echinoderm, and fish blood.

Bethesda, Maryland

Matthias Machner Laboratory, Section on Microbial PathogenesisMethods: Protein purification, human protein-protein interaction microarrays- Investigated human protein binding targets of 2 Legionella pneumophila virulence proteins.

Ithaca, New York Area

Maria Harrison LaboratoryMethods: Fluorescence microscopy, sterile plant culture- Examined the impact of mutations in Medicago truncatula on turnover of arbuscule structures made by endosymbiotic arbuscular mycorrhizal fungi. Results published in Brueillin-Sessoms et al., 2015. The Plant Cell.

Ithaca, New York Area

Ji-Young Lee LaboratoryMethods: DNA extraction, PCR, plant sterile culture- Used PCR to genotype Arabidopsis thaliana, aided with sterile plant culture, and seed collection.

Doctor Of Philosophy (Ph.D.), Virology

Master’S Degree, Pathology

Activities and Societies: Churchill College MCR

Bs, Biological Science, Magna Cum Laude

Activities and Societies: Ho-Nun-De-Kah, Cornell Chamber Orchestra

High School Diploma