James Klimavicz work email
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James Klimavicz personal email
As a Data Architect III at TetraScience, I assess customer scientific use cases, data workflows, and data integration needs, and propose architectural diagrams for improved data workflows. I have a PhD in Organic Chemistry and Toxicology from Iowa State University, and over two years of experience in data architecture and harmonization for life sciences.I also develop and update vendor-agnostic schema for harmonized data ingestion, and serve as a scientific subject matter expert in chromatography. I work with customer data scientists to improve data querying from the TetraScience data platform databases using SQL and ElasticSearch via APIs. I create python scripts for internal and external-facing tools for accessing and reducing data, and updating data labels and metadata. My mission is to keep life sciences data integrated, harmonized, and accessible.
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Computational ScientistOpenbenchCary, Nc, Us
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Data Architect IiiTetrascience Feb 2022 - PresentAssess customer scientific use cases, data workflows, and data integration needs. Propose architectural diagrams for improved data workflows. Develop and update vendor-agnostic schema for harmonized data ingestion. Serve as scientific subject matter expert in chromatography. Work with customer data scientists to improve data querying from the TetraScience data platform databases using SQL and ElasticSearch via APIs. Create python scripts for internal and external-facing tools for accessing and reducing data, and updating data labels and metadata. -
Director Of Discovery And InnovationEnvance Technologies Aug 2020 - Feb 2022Morrisville, North Carolina, United StatesProject leader for the development, synthesis, and assaying of biologically active small molecules with novel modes of action.High-throughput virtual screening of ligand-protein interactions of small molecules for lead compound identification and optimization, incorporating machine learning and clustering for classifying potential compound leadsDevelopment of GCMS methods for qualitative and quantitative analysis of powder-, water-, and oil- based formulations.Whole-organism bioassay development for mode of action and efficacy studies and dose-response analysis with machine learning and computer vision to analyze Drosophila larvaeFormulation development of consumer pest control products with a focus on efficacy and safety to the user. Collaboration with industry partners on product specifications and requirements. -
Discovery And Innovation ScientistEnvance Technologies Feb 2020 - Aug 2020
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Graduate StudentIowa State University Sep 2017 - Aug 2020Ames, IowaPhD Student in Toxicology and ChemistryGraduate Minors in Entomology and StatisticsPreparation, purification, and characterization of more than 400 heterocyclic small molecules and synthetic terpenoid analogs for screening for pesticidal activity. Development of (quantitative) structure-activity relationship models and analysis of dose-response data.Exploration of 30+ novel non-volatile terpenoid-based insecticides for insect baits and seed treatments/coatings and isolation and purification of natural terpenoids from crude extracts and natural oils. Whole-organism in vitro bioassays of biorational pesticides using fungal and bacterial cultures and C. elegans. Substantial interaction with industry partners.
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Graduate StudentUniversity Of Cambridge Sep 2016 - Aug 2017Cambridge, United KingdomMPhil in Scientific Computing, Darwin CollegeExploration of stable conformers and molecular dynamics evaluation of small DNA sequences implicated in genetic diseases and microbiological pathogenesis. Development, implementation, and integration of high-performance computing algorithms written in Fortran 90 into computational chemistry packages for deployment. -
Research ChemistIowa State University Aug 2014 - Sep 2016Ames, IowaPreparation and characterization of synthetic terpenoids for screening for insecticidal activity and insect repellency. Projects include:• Fluorination and functional group transformations of sequiterpenoids • Development of terpenoid-based additives for insect-control baits• Isolation and purification of natural terpenoids from crude extracts and natural oils -
Intramural Research FellowNational Institutes Of Health May 2014 - Aug 2014Bethesda, MdDevelopment and optimization of antibody assays to detect disease using human sera. Projects included:• Searching for novel antibodies in sera for specific diseases, such as tuberculosis and Sjögren’s Syndrome, an autoimmune disease• Synthesis of antibody-luciferase chimera proteins via plasmid ligation for light-based immunoprecipitation studies• Development of high-throughput sera assays to detect potential for disease formation prior to clinically significant symptoms• Statistical analysis of RNA-Seq data to discover trends using mathematic modeling -
Organic Chemistry Teaching AssistantIowa State University May 2011 - May 2014Ames, Iowa
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Graduate StudentIowa State University Aug 2010 - Aug 2013Ames, IowaPreparation and characterization of pi-conjugated monomers for various uses, including organic light emitting diodes, organic field effect transistors, photovoltaics, and fluorescence microscopy. Projects included:• Synthesis of symmetric and asymmetric 2,6-disubstituted benzobisazoles for potential use in organic electronic devices• Development of an innovative method for making orthoesters for synthetic chemistry and biochemical applications
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General Chemistry Teaching AssistantIowa State University Aug 2010 - May 2011
James Klimavicz Skills
James Klimavicz Education Details
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Organic Chemistry And Toxicology
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Scientific Computing
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Gpa: 3.79
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Gpa: 3.88
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Gpa: 3.55
Frequently Asked Questions about James Klimavicz
What company does James Klimavicz work for?
James Klimavicz works for Openbench
What is James Klimavicz's role at the current company?
James Klimavicz's current role is Computational Scientist.
What is James Klimavicz's email address?
James Klimavicz's email address is ja****@****ech.com
What schools did James Klimavicz attend?
James Klimavicz attended Iowa State University, University Of Cambridge, Iowa State University, Iowa State University, Iowa State University.
What are some of James Klimavicz's interests?
James Klimavicz has interest in Science And Technology.
What skills is James Klimavicz known for?
James Klimavicz has skills like Organic Chemistry, Organic Synthesis, Organic Electronics, Spectroscopy, Chemistry, Biochemistry, Nmr, Uv/vis, Fluorescence Spectroscopy, Mass Spectrometry, Chromatography, Chemical Synthesis.
Who are James Klimavicz's colleagues?
James Klimavicz's colleagues are Ivan Solt, Shama Chilakwad, Ken Fountain, Kai Wang, Filipe Cadete, Michał Roztoczyński, Cary Li.
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