Jamie Nosbisch Email & Phone Number

Asheville, Nc, Us

Under the advisement of Dr. Jason Haugh in the Chemical and Biomolecular Engineering Department, I am working on a collaborative project to create a multiscale model of the wound healing process. My work on this project has been focused on modeling the signaling pathway involved in PDGF gradient sensing in fibroblasts which are a particular cell type responsible for wound repair. • I implemented a system of partial differential equations in the software VCell in search of mechanisms in… Show more Under the advisement of Dr. Jason Haugh in the Chemical and Biomolecular Engineering Department, I am working on a collaborative project to create a multiscale model of the wound healing process. My work on this project has been focused on modeling the signaling pathway involved in PDGF gradient sensing in fibroblasts which are a particular cell type responsible for wound repair. • I implemented a system of partial differential equations in the software VCell in search of mechanisms in the signaling pathway that enable the model to qualitatively match live-cell imaging results.• I provided candidate feedback mechanisms to guide experimental work and established a framework from which to assess the roles of other putative feedback loops indicated in the literature.• I used TIRF microscopy to perform live-cell imaging experiments to test model predictions. Show less

The BioLunch Seminar Series is a series of talks given by graduate students or invited academic or industrial professionals on their biology-related research. The goal for this series is to facilitate dialogue and collaboration between different groups as well as to give graduate students a place to practice their presentation skills.• I coordinated and scheduled the 27 graduate student speakers, the external academic and industrial professionals I invited, as well as a professional… Show more The BioLunch Seminar Series is a series of talks given by graduate students or invited academic or industrial professionals on their biology-related research. The goal for this series is to facilitate dialogue and collaboration between different groups as well as to give graduate students a place to practice their presentation skills.• I coordinated and scheduled the 27 graduate student speakers, the external academic and industrial professionals I invited, as well as a professional development activity.• I managed a budget to make sure all of our food purchases each week as well as our funds for the outside speakers were appropriately used. • I successfully wrote a summary/proposal to continue receiving funding for the series from NCSU, and I helped secure additional funding from an outside industry to promote the development of the series.• As a student coordinator for two summers, I have seen the average attendance increase and the audience diversify to include representatives from new programs and departments. Show less

The Department of Education's Graduate Assistance in Areas of National Need (GAANN) Fellowship supported my graduate research work for three years. As part of this fellowship, I took a number of classes to get my minor in Biotechnology including professional development and research ethics classes. I also participated in supervised teaching experiences, took online workshops, and created a portfolio to get the Certificate of Accomplishment in Teaching from the Graduate School at North… Show more The Department of Education's Graduate Assistance in Areas of National Need (GAANN) Fellowship supported my graduate research work for three years. As part of this fellowship, I took a number of classes to get my minor in Biotechnology including professional development and research ethics classes. I also participated in supervised teaching experiences, took online workshops, and created a portfolio to get the Certificate of Accomplishment in Teaching from the Graduate School at North Carolina State University. Show less

I was the teaching assistant for a new course and lab module called High-Throughput Discovery designed to introduce upper-level undergraduates and graduate students to high-throughput technology and the associated data analysis.• I developed aspects of the curriculum including the QuantQuizzes which offered an introduction and practice for basic statistics, calculating Z’-factor scores, calculating IC50 values by using curve-fitting techniques on dose-response data, and examples using… Show more I was the teaching assistant for a new course and lab module called High-Throughput Discovery designed to introduce upper-level undergraduates and graduate students to high-throughput technology and the associated data analysis.• I developed aspects of the curriculum including the QuantQuizzes which offered an introduction and practice for basic statistics, calculating Z’-factor scores, calculating IC50 values by using curve-fitting techniques on dose-response data, and examples using robust statistics.• I modified a lab activity using CellProfiler to familiarize students with using image analysis software. • I graded the QuantQuizzes, lab reports, lab practicals, and helped grade the final presentations and exams. Show less

I taught the mathematics course Calculus for the Life and Management Sciences as a five week summer course. I was responsible for all aspects of this course including developing the lesson plans, creating the course website, writing and grading the exams, assisting with the online homework, and addressing any concerns from the students.

I was a teaching assistant for the mathematics course Calculus I and was responsible for teaching a recitation session each week to review course topics and look over homework problems as well as holding office hours and grading exams.

I was a lecture assistant for the mathematics courses Elements of Calculus and Applied Differential Equations I and was responsible for grading exams and holding office hours.

I learned various microscopy techniques to study biomimetic cell membranes with the goal of identifying the role lipid rafts play in signaling events such as facilitating the first biochemical step of the allergic response in immune cells. • I was introduced to a number of introductory lab protocols including aseptic lab techniques, DNA isolation methods, gel electrophoresis, PCR analyses, etc.• I helped develop and establish a protocol for creating biomimetic membranes on glass… Show more I learned various microscopy techniques to study biomimetic cell membranes with the goal of identifying the role lipid rafts play in signaling events such as facilitating the first biochemical step of the allergic response in immune cells. • I was introduced to a number of introductory lab protocols including aseptic lab techniques, DNA isolation methods, gel electrophoresis, PCR analyses, etc.• I helped develop and establish a protocol for creating biomimetic membranes on glass coverslips.• I used fluorescence microscopy to assess the integrity and uniformity of the biomimetic membranes and fluorescence spectroscopy to characterize the molecular dynamics and lipid diffusion. Show less

I assisted students with understanding material and solving problems in college level chemistry courses including General Chemistry, Organic Chemistry, and Quantitative Analysis.Master Certified Tutor, Level III, College Reading & Learning Association – International Tutor Training Program Certification

I assisted with teaching a chemistry course called Quantitative Analysis. This involved grading exams and helping students during the labs.

Doctor Of Philosophy (Ph.D.), Biomathematics

Minors in Statistics and Biotechnology

Bachelor Of Science (B.S.), Biochemistry And Molecular Biology; Cell And Molecular Biology

Minor in Mathematics Magna Cum Laude with University Honors and Chemistry and Biochemistry Departmental Honors