Jan Grunewald, Ph.D.
AeroLeads people directory · profile

Jan Grunewald, Ph.D. Email & Phone Number

Associate Director at AstraZeneca at AstraZeneca
Location: Washington DC-Baltimore Area, United States, United States 8 work roles 3 schools
1 work email found @gnf.org LinkedIn matched
✓ Verified Jun 2026 4 data sources Profile completeness 100%

Contact Signals · 1 work email

Work email j****@gnf.org
LinkedIn Profile matched
3 free lookups remaining · No credit card
Current company
AstraZeneca
Role
Associate Director at AstraZeneca
Location
Washington DC-Baltimore Area, United States, United States
Company size
78605 employees

Who is Jan Grunewald, Ph.D.? Overview

A concise factual answer block for searchers comparing this professional profile.

Quick answer

Jan Grunewald, Ph.D. is listed as Associate Director at AstraZeneca at AstraZeneca, a company with 78605 employees, based in Washington DC-Baltimore Area, United States, United States. AeroLeads shows a work email signal at gnf.org and a matched LinkedIn profile for Jan Grunewald, Ph.D..

Jan Grunewald, Ph.D. previously worked as Associate Director at Astrazeneca and Associate Principal Scientist at Astrazeneca. Jan Grunewald, Ph.D. holds Doctor Of Philosophy (Ph.D.), Biochemistry from The Philipp University Of Marburg.

Company email context

Email format at AstraZeneca

This section adds company-level context without repeating Jan Grunewald, Ph.D.'s masked contact details.

*@gnf.org
68% confidence

AeroLeads found 1 current-domain work email signal for Jan Grunewald, Ph.D.. Compare company email patterns before reaching out.

View email format View company profile Management contacts
Profile bio

About Jan Grunewald, Ph.D.

I am an experienced biomedical researcher with profound knowledge in protein engineering and bioconjugation to support biotherapeutics discovery. I possess expertise in bacterial, yeast and mammalian cell culture systems, a wide variety of protein purification techniques, as well as multiple biophysical methods for protein characterization. My further specialties encompass protein display technologies, genetic code expansion, secondary metabolite engineering, enzymology and peptide synthesis. I am passionate in training and mentoring fellow scientists to achieve their career goals.Areas of expertise:• Structure-based design of site-specific ADCs and ISACs• Enzyme evolution using display technologies such as yeast display• Site-specific modification of proteins/antibodies by SPAAC, CuAAC, oxime ligation, maleimide-thiol chemistry and enzyme catalysis• Size exclusion, ion exchange, hydrophobic interaction and affinity chromatography of proteins, antibodies and conjugates thereof• Expression and purification of bispecific antibody formats such as CrossMAbs, tandem scFvs, diabodies and two-plus-two tetravalent formats• Generation of bispecifics by site-specific chemical crosslinking of monovalent antibody fragments• Site-specific incorporation of unnatural amino acids into proteins using an expanded genetic code• Solid-phase peptide synthesis and enzyme-catalyzed peptide cyclization• Recombinant protein production in bacteria, yeast, insect cells and mammalian cell lines• FRET-based assays to monitor protein-protein interactions and peptide cyclization• Error-prone PCR, SDS-PAGE, Western blotting, ELISA, RP-HPLC, ESI-MS, MALDI-TOF-MS and UV-Vis spectroscopy

Listed skills include Molecular Biology, Protein Engineering, Protein Chemistry, Biochemistry, and 21 others.

Current workplace

Jan Grunewald, Ph.D.'s current company

Company context helps verify the profile and gives searchers a useful next step.

AstraZeneca
Astrazeneca
Associate Director at AstraZeneca
Gaithersburg, Maryland, United States
Website
astrazeneca.com
Employees
78605
AeroLeads page
Company profile
View company profile Email format
8 roles · 20 years

Jan Grunewald, Ph.D. work experience

A career timeline built from the work history available for this profile.

Role listed

Astrazeneca

Gaithersburg, Maryland, United States

Associate Director

Current
Astrazeneca

Cambridge, Cambridgeshire, GB

Dec 2024 - Present

Associate Principal Scientist

Astrazeneca

Cambridge, Cambridgeshire, GB

Jan 2023 - Nov 2024

Principal Scientist, Head Of Technology Platform

Ambrx

San Diego, CA, US

  • Lead a team of PhD and non-PhD level scientists to design and optimize engineered precisionbiologics (EBPs) using Ambrx’s proprietary expanded genetic code platform
  • Innovate internal expanded genetic code platform by implementing novel SAAs for bacterial andmammalian expression systems (ReCODE/EuCODE technology)
  • Project leader of internal biologics and SAA technology programs
Apr 2021 - Dec 2022

Principal Scientist

Bolt Biotherapeutics, Inc.

Redwood CITY, California, US

  • Spearheading the design and implementation of novel bioconjugation formats for the production of site-specific ISACs with enhanced efficacy and safety
  • Manage outsourcing efforts to streamline the production of homogeneous and chemically-defined ISACs
May 2020 - Apr 2021

Investigator Iii

Gnf

San Diego, CA, US

  • Lead several protein engineering research projects with focuses on antibody-drug conjugation, directed molecular evolution and bispecific antibody pretargeting.
  • Establish a novel enzyme-based conjugation platform for preparing homogeneous, chemically defined antibody-drug conjugates.
  • Design and implement a directed molecular evolution strategy for streamlining enzyme-catalyzed antibody-drug conjugation.
  • Develop and optimize bioorthogonal chemistry protocols for site-specific antibody-drug conjugation, provide expertise on the assessment of proprietary ADC linker/payload combinations.
  • Spearhead the design, cloning, expression, purification and biophysical characterization of multiple bispecific antibody formats for pretargeted therapy.
2014 - Dec 2019

Research Investigator I

Gnf

San Diego, CA, US

  • Act as a lead protein engineer in developing a unique site-specific protein modification platform based on an expanded genetic code.
  • Established genetically encoded pyroline-carboxy-lysine as broadly applicable site-specific conjugation handle to enhance protein functionality and pharmacology.
  • Spearheaded research effort in using proprietary site-specific protein modification platform to develop a FRET-based IgE biosensor for the diagnosis of allergic disease.
  • Developed and optimized a novel protein purification method based on the use of genetically incorporated pyroline-carboxy-lysine as a single amino acid purification tag.
Dec 2008 - 2014

Postdoctoral Researcher

Scripps Research

La Jolla, California, US

  • Laboratory of Peter G. Schultz
  • Joint research project with GNF on overcoming immunological self-tolerance to autologous proteins using an expanded genetic code.
  • Performed construct design, cloning, expression, purification and biophysical characterization of autologous proteins containing the genetically incorporated unnatural amino acid 4-nitrophenylalanine.
  • Demonstrated that mice immunized with 4-nitrophenylalanine-containing tumor necrosis factor elicit a robust neutralizing antibody response against the corresponding autologous protein.
2006 - 2008 ~2 yrs
Team & coworkers

Colleagues at AstraZeneca

Other employees you can reach at astrazeneca.com. View company contacts for 78605 employees →

AN Alexander Nenov Alexander Nenov Colleague at AstrazenecaBulgaria, Bulgaria View → JO Jose Ortiz Jose Ortiz Colleague at AstrazenecaCanóvanas, Puerto Rico, Puerto Rico View → BS Brittany Salzman Castner Brittany Salzman Castner Colleague at AstrazenecaWashington, District Of Columbia, United States, United States View → RB Rebecca Bradley Rebecca Bradley Colleague at AstrazenecaUnited Kingdom, United Kingdom View → VB Vaishnavi Bhadange Vaishnavi Bhadange Colleague at AstrazenecaWardha, Maharashtra, India, India View → RS Ron Sparacino Ron Sparacino Colleague at AstrazenecaOrange County, California, United States, United States View → HA Hanad Ali Hanad Ali Colleague at AstrazenecaStockholm, Stockholm County, Sweden, Sweden View → KD Karin Diem Karin Diem Colleague at AstrazenecaAustria, Austria View → MH Michaela Hrnčářová Zvonková Michaela Hrnčářová Zvonková Colleague at AstrazenecaPrague Metropolitan Area, Czech Republic View → RK Ruzica Kovacek Ruzica Kovacek Colleague at AstrazenecaSödertälje, Stockholm County, Sweden, Sweden View →
3 education records

Jan Grunewald, Ph.D. education

Doctor Of Philosophy (Ph.D.), Biochemistry

The Philipp University Of Marburg

Diploma In Chemistry

The Philipp University Of Marburg

Socrates Program, Physical Chemistry

University Of Cambridge
FAQ

Frequently asked questions about Jan Grunewald, Ph.D.

Quick answers generated from the profile data available on this page.

What company does Jan Grunewald, Ph.D. work for?

Jan Grunewald, Ph.D. works for AstraZeneca.

What is Jan Grunewald, Ph.D.'s role at AstraZeneca?

Jan Grunewald, Ph.D. is listed as Associate Director at AstraZeneca at AstraZeneca.

What is Jan Grunewald, Ph.D.'s email address?

AeroLeads has found 1 work email signal at @gnf.org for Jan Grunewald, Ph.D. at AstraZeneca.

Where is Jan Grunewald, Ph.D. based?

Jan Grunewald, Ph.D. is based in Washington DC-Baltimore Area, United States, United States while working with AstraZeneca.

What companies has Jan Grunewald, Ph.D. worked for?

Jan Grunewald, Ph.D. has worked for Astrazeneca, Ambrx, Bolt Biotherapeutics, Inc., Gnf, and Scripps Research.

Who are Jan Grunewald, Ph.D.'s colleagues at AstraZeneca?

Jan Grunewald, Ph.D.'s colleagues at AstraZeneca include Alexander Nenov, Jose Ortiz, Brittany Salzman Castner, Rebecca Bradley, and Vaishnavi Bhadange.

How can I contact Jan Grunewald, Ph.D.?

You can use AeroLeads to view verified contact signals for Jan Grunewald, Ph.D. at AstraZeneca, including work email, phone, and LinkedIn data when available.

What schools did Jan Grunewald, Ph.D. attend?

Jan Grunewald, Ph.D. holds Doctor Of Philosophy (Ph.D.), Biochemistry from The Philipp University Of Marburg.

What skills is Jan Grunewald, Ph.D. known for?

Jan Grunewald, Ph.D. is listed with skills including Molecular Biology, Protein Engineering, Protein Chemistry, Biochemistry, Purification, Protein Expression, Protein Purification, and Mutagenesis.

Find 750M verified contacts

Search by job title, company, industry, location, and seniority. Export verified B2B contact data when you need it.