• Lead a laboratory investigating the genomic and molecular mechanisms of host immunity. Funding from the National Institutes of Health, Centers for Disease Control and Prevention, Jeffrey Modell Foundation, and Boston Children’s Hospital.• Developed strategies for the diagnosis of rare immune disorders, using multi-omic technologies, cellular and molecular assays, and mouse models of human disease. • Immunology lead for a multi-center, national study of SARS-CoV-2 infections in children, funded by the Centers for Disease Control and Prevention.

• Direct the clinical functions of the largest pediatric clinical immunology program in the U.S.• Develop clinical pathways for the diagnosis and treatment of new diseases and emerging pathogens.• Developed strategies for allocation of limited clinical resources, including intravenous immunoglobulins and COVID-19 vaccines.

• Established and lead the operation of the Division’s next-generation sequencing platform for the identification of genomic causes and biomarkers of immune disorders.• Experienced in leading matrix teams of clinicians, scientists, and computational biologists in the identification and functional validation of genetic variants underlying disorders of host immunity.

• Developed a translational research infrastructure integrating clinicians and scientists in 40 medical centers in 25 countries for the discovery of new immune disorders affecting global populations.