Jan-Philip Schülke Email & Phone Number

Munich, By, De

Freising, By, De

Freising, De

Freising, De

• Providing proteomic services for drug discovery research.

Hamburg, De

• Project leader in chemical biology providing proteomic services for clients to identify molecular targets and mechanisms of action.• Interfacing between customers and laboratory scientists: Discuss and evaluate project requests with customers; lead experiments conducted by laboratory scientists; analyze and report data.• Key point of contact in Munich for a large customer working on neurodegenerative diseases.

Cambridge, Cambridgeshire, Gb

• Led the newly formed exploratory biology laboratory focusing on the identification and validation of novel targets for psychiatric and neurodegenerative diseases.• Collaborated within AZ Discovery Sciences and external partners of AZ Neuro.

New York, New York, Us

• Implemented systems biological strategies into the drug development pipeline to aid in improved target selection and identification of novel biomarkers.• Developed chemoproteomic strategies to characterize target engagement, drug-target interactions and to support target deconvolution of phenotypic screens.• Contributor in a collaborative project between academia and industry that reported a human mutation in PDE10A causing a movement disorder.• Postdoc committee member.

• Investigated the mechanism of action of the effect of DRR1 on Actin function.• Guidance and training of an undergraduate student throughout Master thesis project.

Doctoral thesis in the laboratory of Dr. Theo Rein.• Analyzed molecular pathways of stress-related psychiatric diseases.• Identified the molecular function of the stress-regulated protein DRR1, as a novel regulator of synaptic plasticity by altering actin dynamics.• Investigated the roles of molecular chaperones in the regulation of steroid-hormone receptors.• Gained insight about neuropsychiatric disease research in a clinical setting.

Lincoln, Canterbury, Nz

Agresearch, Wallaceville Animal Research Centre, in Upper Hutt (New Zealand), in the laboratory of Dr. Ken McNatty.• Investigated the roles of bone morphogenetic proteins in early follicular development.

Phd, Biochemistry

Diploma/Master, Biology