Management of Quality Control projects and improve/sustain level of quality within the organisation.

Synaffix got acquired by Lonza in 2023.Synaffix is a biotechnology company focused on the continued advancement of its best-in-class antibody-drug conjugate (ADC) technology platform. Synaffix is a leading innovator in the field of ADCs and strives to become the preferred partner in the development of these complex biological therapeutics.Working in R&D (see previous experiences) and experience in CMC project management:• Planning and coordinating activities performed at CRO and C(D)MO• Identifying and solving bottle necks (upscaling, regulations etc.) • Manufacturing under (non-)GMP regulations• Judging project proposals (work, timelines, budget)• Providing (technical) input for contracting • Writing investigational new drug (IND) application• Developing stable cell lines (bacterial, CHO)

As a Research Scientist, experience with;- Leading and execute material transfer agreements for clients (ADCs)- Coordinating research and development projects- Developing stable cell lines (bacterial, CHO)- Process development (Upstream & Downstream)- Formulation development of proteins- Protein expression- Bioconjugation- Assay development

Development and investigation of novel diagnostic and therapy concepts by making use of the hybridizing nature of DNA. Peptide synthesis, protein expression, (DNA-)conjugation strategies. Purification and characterization of synthesized molecules followed by diverse biochemical assays. Relevant analytical techniques: Mass spectometry, fluorescence spectroscopy, flowcytometry, (size exlusion) chromatography.Supervising students (graduation project, internship).

Intern in the W. Shih lab, structural DNA-nanotechnology. The focus of my stay was DNA-origami and exploring a novel DNA-conjugation method.

Introducing bachelor-students to the principles of techniques often used in biochemistry.

Synthesis and characterization of FRET-based Cu(I)-sensors.