Delivered clinical biomarker analysis as part of a team working to establish regulatory guidance for biosimilars. Developed and optimized assays for the quantification of endogenous biomarkers in support of clinical endpoints.

Delivered bioanalysis for 450+ studies in support of Pfizer’s discovery portfolio; reduced study turnaround time by more than 50% through process re-engineering, enabling rapid decision making at the leadership level. Owned data collection, analysis, and reporting for projects across multiple therapeutics areas (oncology, inflammation & immunology, internal medicine, & rare disease)- Designed and implemented new intranet site (SharePoint) to streamline knowledge management; launched centralized bioanalytical and logistics dashboards, improving user navigation resulting in increased operational efficiency- Developed and validated a clinical biomarker assay for the evaluation of renal transporter drug-drug interactions in early-stage clinical trials; applied to four first-in-human clinical trials to demonstrate utility and commercial value - Optimized critical assays supporting programs utilizing nanoparticle formulations; assay improvements provided key data endpoints, enabling in-depth data modeling and driving strategic decision making at the executive level- Developed and analyzed 7 endogenous probes and their respective metabolites in support of a novel biomarker initiative for cytochrome P450 isoforms and other drug metabolizing enzymes

Provided in vitro assay support for small molecule candidates and spearheaded technology initiatives - Conducted in vitro assays to evaluate the effects of drug candidates as inhibitors of drug metabolism enzymes- Managed data collection, analysis, and reporting required for investigational new drug (IND) applications with regulatory agencies

Investigated various hypotheses pertaining to chronic alcohol abuse and Alzheimer's disease- Conducted shotgun lipidomic analyses; designed automated sample extraction processes and high-throughput data collection techniques; contributing author to publications pertaining to alcoholism and Alzheimer's disease- Designed and programmed automated liquid handling procedures; expedited sample preparation and improved data quality and reproducibility

Assessed the impact of chronic cigarette smoke exposure on hepatic lipid profiles using mass spectrometry

Mentored students on course materials covering end-to-end biotechnology product life-cycle management;- Biotechnology in Medicine: relevant medical technologies functions and their applications; drug discovery and regulatory processes required to bring drugs and medical devices to market - Biomaterials: biological requirements associated with contemporary medical devices; functions and design considerations of implantable and extracorporeal devices