Jarrod Shilts

Jarrod Shilts Email and Phone Number

Engineer building with the molecules of life @ ExpressionEdits
Jarrod Shilts's Location
Cambridge, England, United Kingdom, United Kingdom
Jarrod Shilts's Contact Details

Jarrod Shilts work email

Jarrod Shilts personal email

n/a
About Jarrod Shilts

Jarrod Shilts is a Engineer building with the molecules of life at ExpressionEdits.

Jarrod Shilts's Current Company Details
ExpressionEdits

Expressionedits

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Engineer building with the molecules of life
Jarrod Shilts Work Experience Details
  • Expressionedits
    Group Leader
    Expressionedits 2024 - Present
  • Expressionedits
    Lead Scientist For Research & Development
    Expressionedits 2022 - 2024
    ► Co-founding member of a biotech start-up that is finding ways to re-invent how recombinant proteins and transgene therapies are manufactured.► Establishing our core technology platform through work both in the laboratory and done computationally. In parallel, I am guiding the company's scientific strategy as we grow, in close coordination with our team.
  • Wellcome Sanger Institute
    Research Scientist
    Wellcome Sanger Institute 2017 - 2022
    Cell Surface Signaling Laboratory
    ► Invented a technique for comprehensively measuring how receptor proteins interact, achieving more than a 10-fold increase in scale and sensitivity compared to previously existing methods► Built a high-throughput pipeline with robotics and streamlined recombinant protein production that enabled carrying out the largest receptor interaction screens yet published at the time.► Discovered multiple novel receptor interactions that provided the missing pieces to resolve clinical mysteries or unappreciated biological mechanisms, including discovering the natural ligand to a major immunotherpay target, a cancer-associated protein linked to immune evasion, and a neuronal receptor directing synaptic plasticity. ► Adapted the technologies I developed to aid the scientific response to the COVID-19 Pandemic, which resulted in the discovery of two viral receptors which were later independently replicated and found to explain how some are more susceptible to severe viral infection than others.► Computationally integrated the large-scale biochemical datasets I generated with single-cell resolution expression data to map receptor-mediated cell-to-cell connections across the human body. Used these integrated data sources to construct a mathematical model that predicts from biophysical first-principles the behaviors of collections of cells.
  • Vanderbilt University School Of Engineering
    Sybbure-Searle Program Fellow
    Vanderbilt University School Of Engineering 2015 - 2017
    Vanderbilt Institute For Integrative Biosystems Research And Education
    ► Worked together with highly multi-disciplinary groups of students spanning fields of engineering, including completing projects in fabricating microfluidic devices, biomedical data analytics, and designing genetic circuits.► Assisted as a program coordinator, advising students on their projects and organizing team-building activities.
  • Vanderbilt University Medical Center
    Research Assistant
    Vanderbilt University Medical Center 2014 - 2017
    ► Investigated a previously-intractable gene's role in Drosophila neural development by being among the first in the department to implement CRISPR genome editing. Included independent work in genetics, immunohistochemistry, behavioral testing, live-cell functional assays, and automated image analysis.►Applied a statistical model to gene expression data from human cancer patients to quantify how cancer disrupts the internal functioning of the circadian clock.

Jarrod Shilts Education Details

Frequently Asked Questions about Jarrod Shilts

What company does Jarrod Shilts work for?

Jarrod Shilts works for Expressionedits

What is Jarrod Shilts's role at the current company?

Jarrod Shilts's current role is Engineer building with the molecules of life.

What is Jarrod Shilts's email address?

Jarrod Shilts's email address is ja****@****its.com

What schools did Jarrod Shilts attend?

Jarrod Shilts attended University Of Cambridge, University Of Cambridge, Vanderbilt University.

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