Jason Gerstner

Jason Gerstner Email and Phone Number

Assistant Professor @ WSU Elson S. Floyd College of Medicine
Spokane, WA, US
Jason Gerstner's Location
Spokane, Washington, United States, United States
Jason Gerstner's Contact Details

Jason Gerstner personal email

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About Jason Gerstner

I am currently working in the Elson S. Floyd College of Medicine at Washington State University- Spokane. Previously I discovered and characterized the unique time-of-day cycling of the brain-type fatty-acid binding protein (Fabp7) in mammalian brain (Gerstner et al., 2006; Gerstner et al., 2008). What made these findings novel was that prior to these observations, it was not known whether oscillations in specific transcripts of cycling genes occur in phase brain-wide, since canonical 'clock' genes cycle out of phase in extra-SCN areas. Given the importance of cycling molecules in memory formation (Gerstner and Yin, 2010), I then cloned and characterized the Fabp7 homologue dFabp in the fruit fly Drosophila melanogaster, and made transgenic flies that over-express the murine Fabp7 or dFabp, in order to test whether changes in Fabp levels confer sleep and memory phenotypes (Gerstner et al., 2011a; Gerstner et al., 2011b). I then explored the subcellular localization of Fabp7 in the mouse model, where relative levels of Fabp7 mRNA concentration oscillate in the perisynaptic process compartment over the light-dark cycle in astrocytes (Gerstner et al., 2012). We have now established that the astrocyte Fabp7 gene is necessary for normal sleep in flies, mice, and humans (Gerstner et al., 2017). Current studies are identifying astrocyte pathways involved in regulating sleep, and the relationship between these events and neurodegenerative disease etiology, such as ALS, Alzheimer's, and Parkinson's diseases.Specialtiessleep and circadian rhythms, cellular and molecular biology, genetics, synaptic plasticity, neurobiology of learning and memory, neurometabolic coupling, glia

Jason Gerstner's Current Company Details
WSU Elson S. Floyd College of Medicine

Wsu Elson S. Floyd College Of Medicine

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Assistant Professor
Spokane, WA, US
Jason Gerstner Work Experience Details
  • Wsu Elson S. Floyd College Of Medicine
    Assistant Professor
    Wsu Elson S. Floyd College Of Medicine
    Spokane, Wa, Us
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  • Wsu Elson S. Floyd College Of Medicine
    Assistant Professor
    Wsu Elson S. Floyd College Of Medicine Aug 2020 - Present
    Spokane, Washington, United States
    - Studying the interplay of molecular mechanisms regulating sleep and plasticity- Using bioinformatics to evaluate changes in glial-gene expression profiles- Using genetic manipulations in mice and Drosophila melanogaster to study astrocyte biology and behavior- Testing compounds in neurodegenerative disease models for the relationship between sleep disruption and pathology
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  • Soluble Oak
    Mad Scientist
    Soluble Oak Nov 2024 - Present
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  • Elson S. Floyd College Of Medicine, Washington State University Spokane
    Research Assistant Professor
    Elson S. Floyd College Of Medicine, Washington State University Spokane Jun 2014 - Aug 2020
    Spokane, Washington Area
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  • University Of Pennsylvania
    Postdoctoral Researcher
    University Of Pennsylvania Oct 2013 - Jun 2014
    Department Of Neuroscience
    Laboratory of Marcos G. Frank, Ph.D. Postdoctoral research on the interaction between the genetics underlying changes in neural-glial interactions, synaptic plasticity and sleep behavior.
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  • University Of Pennsylvania School Of Medicine
    Post-Doctoral Fellow
    University Of Pennsylvania School Of Medicine Jul 2010 - Sep 2013
    Center For Sleep And Circadian Neurobiology Translational Research Laboratories
    Laboratory of Allan Pack, M.B.Ch.B., Ph.D. Postdoctoral research on the molecular mechanisms underlying sleep, circadian rhythms in mice and flies.- Designed custom sleep analysis program for fly, mouse, and human actigraphy- Utilizing transgenic models of Alzheimer’s disease- Worked with genetic mouse models relating synaptic plasticity, epilepsy, and metabolism- Supported by NIH grant 5T32HL007713 (2010-2013)
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  • University Of Wisconsin-Madison
    Research Associate
    University Of Wisconsin-Madison Sep 2008 - Jul 2010
    Department Of Genetics
    Post-doctoral research- Developed conditional expression models in Drosophila to direct spatial-temporal control of transgenes for analysis in behavior- Sleep Research Society Abstract Excellence Award, APSS Sleep Meeting, 2009- Travel Award, Janelia Conference: Sleep in Non-Mammalian Models, 2009- Tailored sleep deprivation and sleep/activity recording in flies to evaluate genetic intersection of sleep/circadian rhythms with learning & memory- Used a reverse genetic approach to study sleep in various mutant fly strains- Mentored 4 graduate students, 3 undergraduate students, 1 technician
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  • University Of Wisconsin-Madison
    Graduate Student
    University Of Wisconsin-Madison Jun 2003 - Aug 2008
    Neuroscience Training Program
    Laboratory of Jerry CP Yin, Ph.D. Used Drosophila neurogenetics to characterize Fabp expression effects on sleep and memory formation.- Generated transgenic flies for conditional expression of target genes- Constructed/utilized olfactory avoidance conditioning apparatus for fly memory- Mentored 7 undergraduate students, 3 technicians- Supported by NIH grant 5T32GM007507 (2003-2006)
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Jason Gerstner Skills

Neuroscience Molecular Biology Biochemistry Genetics Immunohistochemistry Animal Models Fluorescence Microscopy Protein Chemistry Western Blotting Cell Biology In Vivo Confocal Microscopy Immunofluorescence Bioinformatics Qpcr Life Sciences Research Tissue Culture Science Transfection Cell Culture Lifesciences Laboratory Signal Transduction Molecular Cloning Protein Expression Developmental Biology Mouse Models Pcr Electrophysiology Physiology Synaptic Plasticity Circadian Rhythms Polymerase Chain Reaction Microscopy Scientific Writing

Jason Gerstner Education Details

Frequently Asked Questions about Jason Gerstner

What company does Jason Gerstner work for?

Jason Gerstner works for Wsu Elson S. Floyd College Of Medicine

What is Jason Gerstner's role at the current company?

Jason Gerstner's current role is Assistant Professor.

What is Jason Gerstner's email address?

Jason Gerstner's email address is jr****@****isc.edu

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Jason Gerstner's direct phone number is +160826*****

What schools did Jason Gerstner attend?

Jason Gerstner attended University Of Wisconsin-Madison, University Of Wisconsin-Madison, University Of Wisconsin-Madison.

What skills is Jason Gerstner known for?

Jason Gerstner has skills like Neuroscience, Molecular Biology, Biochemistry, Genetics, Immunohistochemistry, Animal Models, Fluorescence Microscopy, Protein Chemistry, Western Blotting, Cell Biology, In Vivo, Confocal Microscopy.

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