Jason R. Spence Email and Phone Number
Jason R. Spence work email
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Jason R. Spence personal email
My laboratory focuses on stem cell and developmental biology. One of the major goals of this work is to use the information gained from basic developmental biology to direct the differentiation of pluripotent stem cells into specific tissue lineages. We have developed a novel system that utilizes human embryonic and induced pluripotent stem cells to generate mature intestinal tissue in culture, called human intestinal organoids (HIOs). We use HIOs in addition to mouse organoids (enteroids) to study intestinal homeostasis and stem cell regulation. Our long-term goal is to use both mouse development and human stem cells in order to gain an in-depth appreciation for the complexity of normal embryonic development, and to begin to translate our findings so that we can generate human models to study disease processes, screen drugs, understand gene function and generate therapeutically useful tissue for transplantation.
Intero Biosystems
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Co-Founder And Chief Scientific OfficerIntero Biosystems Feb 2024 - PresentAnn Arbor, Michigan, United StatesOrganoids: The Future of Predictive Human ModelsOrganoids are miniature human models that retain the spatial organization and function of the organ of interest. Intero Biosystems is based on technology developed in the Spence Lab at the University of Michigan. Intero is developing a miniature model of the human intestine that allows drugs to be tested on human organs before going to human clinical trials: mitigating risk, reducing cost in clinical trials, and identifying safer, more effective drugs for patients in need. -
ProfessorUniversity Of Michigan Sep 2021 - Present -
Associate ProfessorUniversity Of Michigan Sep 2016 - Sep 2021Ann Arbor, Michigan -
Assistant ProfessorUniversity Of Michigan Medical School Oct 2011 - Aug 2016 -
Research FellowCincinnati Children'S Hospital Oct 2006 - Sep 2011
Jason R. Spence Skills
Jason R. Spence Education Details
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Miami UniversityCell/Cellular And Molecular Biology -
Canisius CollegeBiology
Frequently Asked Questions about Jason R. Spence
What company does Jason R. Spence work for?
Jason R. Spence works for Intero Biosystems
What is Jason R. Spence's role at the current company?
Jason R. Spence's current role is Professor at the University of Michigan Medical School, Co-Founder - Intero Biosystems.
What is Jason R. Spence's email address?
Jason R. Spence's email address is ja****@****ich.edu
What schools did Jason R. Spence attend?
Jason R. Spence attended Miami University, Canisius College.
What are some of Jason R. Spence's interests?
Jason R. Spence has interest in Developmental Biology, Science, Human Pluripotent Stem Cells, Regenerative Medicine, Lungs, Intestines.
What skills is Jason R. Spence known for?
Jason R. Spence has skills like Stem Cells, Developmental Biology, Science, Molecular Biology, Cell Biology, Scientific Writing, Regenerative Medicine, Research, Stem Cell Technology, Project Management, Problem Solving, Collaborative Problem Solving.
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