Jason R. Spence

Jason R. Spence Email and Phone Number

Professor at the University of Michigan Medical School, Co-Founder - Intero Biosystems @ Intero Biosystems
Jason R. Spence's Location
Ann Arbor, Michigan, United States, United States
Jason R. Spence's Contact Details

Jason R. Spence work email

Jason R. Spence personal email

n/a
About Jason R. Spence

My laboratory focuses on stem cell and developmental biology. One of the major goals of this work is to use the information gained from basic developmental biology to direct the differentiation of pluripotent stem cells into specific tissue lineages. We have developed a novel system that utilizes human embryonic and induced pluripotent stem cells to generate mature intestinal tissue in culture, called human intestinal organoids (HIOs). We use HIOs in addition to mouse organoids (enteroids) to study intestinal homeostasis and stem cell regulation. Our long-term goal is to use both mouse development and human stem cells in order to gain an in-depth appreciation for the complexity of normal embryonic development, and to begin to translate our findings so that we can generate human models to study disease processes, screen drugs, understand gene function and generate therapeutically useful tissue for transplantation.

Jason R. Spence's Current Company Details
Intero Biosystems

Intero Biosystems

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Professor at the University of Michigan Medical School, Co-Founder - Intero Biosystems
Jason R. Spence Work Experience Details
  • Intero Biosystems
    Co-Founder And Chief Scientific Officer
    Intero Biosystems Feb 2024 - Present
    Ann Arbor, Michigan, United States
    Organoids: The Future of Predictive Human ModelsOrganoids are miniature human models that retain the spatial organization and function of the organ of interest. Intero Biosystems is based on technology developed in the Spence Lab at the University of Michigan. Intero is developing a miniature model of the human intestine that allows drugs to be tested on human organs before going to human clinical trials: mitigating risk, reducing cost in clinical trials, and identifying safer, more effective drugs for patients in need.
  • University Of Michigan
    Professor
    University Of Michigan Sep 2021 - Present
  • University Of Michigan
    Associate Professor
    University Of Michigan Sep 2016 - Sep 2021
    Ann Arbor, Michigan
  • University Of Michigan Medical School
    Assistant Professor
    University Of Michigan Medical School Oct 2011 - Aug 2016
  • Cincinnati Children'S Hospital
    Research Fellow
    Cincinnati Children'S Hospital Oct 2006 - Sep 2011

Jason R. Spence Skills

Stem Cells Developmental Biology Science Molecular Biology Cell Biology Scientific Writing Regenerative Medicine Research Stem Cell Technology Project Management Problem Solving Collaborative Problem Solving Experimentation Experimental Design Experimental Analysis Biology Embryonic Stem Cells Stem Cell Research Adult Stem Cells

Jason R. Spence Education Details

  • Miami University
    Miami University
    Cell/Cellular And Molecular Biology
  • Canisius College
    Canisius College
    Biology

Frequently Asked Questions about Jason R. Spence

What company does Jason R. Spence work for?

Jason R. Spence works for Intero Biosystems

What is Jason R. Spence's role at the current company?

Jason R. Spence's current role is Professor at the University of Michigan Medical School, Co-Founder - Intero Biosystems.

What is Jason R. Spence's email address?

Jason R. Spence's email address is ja****@****ich.edu

What schools did Jason R. Spence attend?

Jason R. Spence attended Miami University, Canisius College.

What are some of Jason R. Spence's interests?

Jason R. Spence has interest in Developmental Biology, Science, Human Pluripotent Stem Cells, Regenerative Medicine, Lungs, Intestines.

What skills is Jason R. Spence known for?

Jason R. Spence has skills like Stem Cells, Developmental Biology, Science, Molecular Biology, Cell Biology, Scientific Writing, Regenerative Medicine, Research, Stem Cell Technology, Project Management, Problem Solving, Collaborative Problem Solving.

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