Jason Rush, Ph. D. Email and Phone Number
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Chemical biologist with deep experience in protein biochemistry, molecular biology, biochemical and cellular assay development, high throughput screening as well as leading collaborative therapeutics projects involving non-traditional targets in fast-paced, matrixed environments.
Broad Institute Of Mit And Harvard
View- Website:
- broadinstitute.org
- Employees:
- 3212
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Group Leader, Research ScientistBroad Institute Of Mit And HarvardCambridge, Ma, Us -
Group LeaderBroad Institute Of Mit And Harvard Jul 2022 - PresentCambridge, Ma, Us -
Senior Research Scientist IBroad Institute Of Mit And Harvard Jan 2021 - PresentCambridge, Ma, Us -
Research Scientist IiBroad Institute Of Mit And Harvard Jan 2016 - Jan 2021Cambridge, Ma, Us• Co-project team lead pursuing therapeutics for IBD by inhibiting protein-protein interactions in innate immunity.• Developed homogenous and bead-based HTS-compatible assays to monitor protein-protein interactions, E3 substrate ubiquitinylation, cellular target engagement and target protein abundance.• Bolstered screening efforts by expression and purification of proteins using mammalian, insect and E. coli systems. -
Research Scientist IBroad Institute Of Mit And Harvard Jul 2014 - Jan 2016Cambridge, Ma, Us• Integrated into Dr. Ramnik Xavier’s research group within the Broad Institute• Investigated the role of an E3 ligase on innate immune signaling in myeloid cells• Explored the mechanism of a rare allele associated with strong protection against Crohns’ disease -
Postdoctoral Associate With Prof. Andrew PhillipsYale University Jan 2012 - Jun 2014New Haven, Ct, Us• Investigated how privileged small molecules (e.g. antibiotics, microbial hormones) impacted microbes' secondary metabolomes.• Developed affinity-based technology to identify transcription factor ligands that regulate microbial secondary metabolic pathways. -
Post-Doctoral Associate With Prof. Jo HandelsmanYale University 2009 - Dec 2011New Haven, Ct, Us• Investigated the roles of microbial small molecule communication in lepidopteron guts.• Examined how co-culture of diverse microbes impacted their secondary metabolomes. -
Graduate Research With Prof. Carolyn R. BertozziUc Berkeley Aug 2003 - May 2009Berkeley, Ca, Us• Developed a chromatography-free synthesis of an alpha-formylglycine building block for solid-phase peptide synthesis.• Created and utilized a plate-based assay to explore the substrate sequence space of the aldehyde tag-forming formylglycine generating enzyme.• Synthesized sulfatase-activated chemical probes to aid in the research of sulfatase and to search for cryptic formylglycine generating enzyme activities.
Jason Rush, Ph. D. Skills
Jason Rush, Ph. D. Education Details
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University Of California, BerkeleyChemistry -
University Of MichiganChemistry
Frequently Asked Questions about Jason Rush, Ph. D.
What company does Jason Rush, Ph. D. work for?
Jason Rush, Ph. D. works for Broad Institute Of Mit And Harvard
What is Jason Rush, Ph. D.'s role at the current company?
Jason Rush, Ph. D.'s current role is Group Leader, Research Scientist.
What is Jason Rush, Ph. D.'s email address?
Jason Rush, Ph. D.'s email address is jr****@****mit.edu
What schools did Jason Rush, Ph. D. attend?
Jason Rush, Ph. D. attended University Of California, Berkeley, University Of Michigan.
What skills is Jason Rush, Ph. D. known for?
Jason Rush, Ph. D. has skills like Molecular Biology, Chemical Biology, Microbiology, Synthetic Organic Chemistry, Mass Spectrometry, Biochemistry, Protein Expression, Pcr, Life Sciences, Chemistry, Hplc, Molecular Cloning.
Who are Jason Rush, Ph. D.'s colleagues?
Jason Rush, Ph. D.'s colleagues are Barbra Bergman, Chidimma Nzerem, Tanay Thakar, Shailendra Dhakal, Ph.d., Ishan Misro, Valerie Smith, Vladislav Cherdantsev.
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