Jason Baum Email & Phone Number

Cambridge, Ma, Us

Cambridge, Ma, Us

Responsible for the design and execution of Leap’s translational medicine strategy including:- Leading the Translational Medicine and Research teams responsible for companion diagnostic development, clinical biomarker execution and pre-clinical research- Serving as a member of Leap’s Senior Management Team helping to lead the company's strategy, clinical development decisions and investor/business development discussions. Played a key role in a successful fundraising in Sept 2021, and the acquisition of Flame Biosciences in January 2023

Basel, Baselstadt, Ch

Accountable for the end-to-end design and delivery of the Precision Medicine strategy. This includes the development, implementation and execution of biomarker strategies and companion diagnostics to support regulatory endpoints, patient selection, stratification, monitoring and exploratory efforts • Program responsibilities include high priority therapeutics in Lung Cancer and >15 therapeutics in General Medicine (Neuroscience, Cardiovascular-Metabolic, Ophthalmology and Global Health)• Lead additional Precision Medicine efforts for Novartis Affiliates including Sandoz Biosimilars and AveXis Gene Therapies• Serve as a core member on the Precision Medicine Leadership team and Global Program Teams within Oncology and General Medicine • Drive the implementation of the strategic plan in collaboration with key stakeholders • Lead sub-teams to design, implement and execute the precision medicine strategy and scientific narrative• For CDx and IVD assays, oversee the design of the Target Product Profile to ensure approval, market access and optimized commercial value• Lead the exploratory biomarker strategy to support understanding of MoA, prognostic and predictive response markers, mechanisms of resistance and enable future indications and combinations• Ensure the biomarker portions of key clinical documents including Submission Documents, Clinical Development Plans, Clinical Study Protocols, Investigator Brochures, and Clinical Study Reports are completed in a timely manner• Support regulatory submissions by acting as subject matter expert within the team.• Direct contact with external groups including medical experts, health authorities and diagnostic partners.• Manage six direct reports including Directors and Associate Directors. Support their development and alignment with achieving objectives and adhering to Novartis values• Recognized at the 2019 Oncology Leadership Forum as a key impact maker for scientific contributions to the Canakinumab program.

Basel, Baselstadt, Ch

Precision Medicine Director, supporting the development of Oncology Precision Medicine's (OPM’s) strategy for targeted and immuno-oncology therapeutics in NSCLC. - Oversee implementation of the NSCLC OPM strategy, with predominant focus on the development and execution of biomarker activities and ensuring approval of Companion Diagnostic (CDx) assays.- Responsible for the execution of assay development for patient selection, stratification, pharmacodynamics, correlative studies and CDx development by working with internal stakeholders and external partners- Serve as a core member of the of the Global Program Team (GPT) and Global Clinical Teams.

Cambridge, Massachusetts, Us

Lead Merrimack's diagnostic and biomarker team, overseeing the full path from biomarker identification to clinical implementation and CDx approvalServe as the diagnostic head on Merrimack's expanded management teamCompanion Diagnostic Project Lead for Seribantumab (MM-121):- Lead the companion diagnostic development and path to PMA - Ensure close alignment with the therapeutic development strategyOversee the development and implementation of diagnostic strategies:- Liaise with IVD partners and CLIA labs externally, as well as clinical operations, BD, regulatory, research and commercial groups internally- Support the planning and execution of clinical trials- Implement diagnostic assays for clinical use and prospective patient selection at CLIA labs- Lead the preparation, submission and presentation of CDx regulatory documents including pre-submissions, IDEs and risk assessments- Work with earlier stage therapeutic teams to develop their biomarker and CDx strategies- Bring new assay/platform capabilities in house to support clinical biomarker analysis- Provide technical expertise across biomarker platforms (including ISH, IHC, ELISA, NGS)- Assist in writing lab manuals and translational protocols to support the planning and execution of clinical trialsLead GCLP Lab Operations- Clinical sample receipt and tracking via LIMS, biobanking, histology, blood processing

Cambridge, Massachusetts, Us

Cambridge, Massachusetts, Us

Cambridge, Massachusetts, Us

Danvers, Ma, Us

Ba, Biology

Phd, Cell Biology, Molecular Biology And Biochemistry