Jasper Jacobs Email & Phone Number

Paris, France, Fr

Project Head Innovation within Sanofi's Large Molecules Research Platform.Striving to deliver breakthrough science and transformative technologies into Sanofi's early development pipeline of biotherapeutics.Coordinating innovation projects across different therapeutic (oncology, immunology, inflammation, rare diseases) and technological areas (synthetic biology, bioconjugates, conditional activation, de novo design, alternative scaffolds, alternative delivery)Closely collaborating with various internal stakeholders (therapeutic areas, research platforms, discovery research, CMC, development, IP, BD, digital, ...) and external (academic/industry) partners.

Zwijnaarde (Ghent), Be

Senior Scientist Bioassay DevelopmentResponsible for the design, development and qualification of GMP-ready potency bioassays in support of all therapeutic Nanobody projects, in accordance to ICH/USP/Ph. Eur. guidelines. Planning, coordination and supervision of lab activities.Specialized in novel and complex mechanisms of action (multi-specifics, immune-cell engagers, drug-conjugates) across different therapeutic areas, with a focus on immune-oncology and inflammation.Subject matter expert on bioassays and in vitro pharmacology.

Zwijnaarde (Ghent), Be

Zwijnaarde (Ghent), Be

Support non-clinical development of candidate Nanobody-based therapeuticsResponsible for development, qualification, validation and transfer of GMP-ready QC bioassays for Nanobody lot release and stability testing (potency assays), according to international guidelines (ICH, USP, Ph.Eur, FDA)Subject matter expert on development and validation of bioanalytical methods (PK & biomarker) in various matrices and therapeutic areasSubject matter expert on in-vitro pharmacology studies for new Nanobody-based drug candidates (affinity determination, mechanism-of-action studies, species cross reactivity, ...)Involved in preclinical in-vivo & ex-vivo study design, execution and monitoring (efficacy / PKPD / safety)GLP-compliant and clinical study support

Zwijnaarde (Ghent), Be

Zwijnaarde (Ghent), Be

Zwijnaarde (Ghent), Be

Master In Science, Biochemistry & Biotechnology

Science-Maths