Jay Duffner

Jay Duffner Email and Phone Number

Associate Director of Discovery Biology @ Frontier Medicines
Jay Duffner's Location
Cambridge, Massachusetts, United States, United States
About Jay Duffner

Research and discovery are my passions. I look forward to elucidating each unknown and to working with my colleagues to advance early phase drugs to human trials. My most recent position as associate director of biophysics at Faze Medicines involved utilizing biophysical techniques to elaborate lead programs in neurology and oncology. In addition, I developed plans for new drug discovery programs.Prior to Faze I worked in immonology as a translational scientist at Janssen Pharmaceuticals and in several different drug discovery and development roles at Momenta Pharmaceuticals. Throughout my career I have always enjoyed the problem solving aspects of research and the process and planning that leads to successful research programs..I currently lead a program at Momenta with a group of researchers looking to optimize the characteristics of glycoprotein therapeutics through in vitro and in vivo manipulation.While I enjoy managing programs, I also relish laboratory work and am well-versed in current techniques used to study biomolecular interactions (Biacore), CRISPR genome modification, gene expression analysis (both wet-lab and data analysis workflows).

Jay Duffner's Current Company Details
Frontier Medicines

Frontier Medicines

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Associate Director of Discovery Biology
Jay Duffner Work Experience Details
  • Frontier Medicines
    Associate Director Of Discovery Biology
    Frontier Medicines Mar 2023 - Present
    South San Francisco, Ca, Us
    Discovering covalent small molecules to drug the undrugable. Employing biochemical and biophysical techniques for hit finding, hit triage, lead discovery and drug candidate nomination.
  • Faze Medicines
    Associate Director, Biophysics
    Faze Medicines Jan 2022 - Nov 2022
    Cambridge, Massachusetts, Us
    Associate director of biophysics in a drug discovery team researching small molecules that perturb the functions of biomolecular condensates relevant to disease biology. Managed CROs and research plans for biomolecular interactions. Developed drug discovery plans for new targets in oncology.
  • The Janssen Pharmaceutical Companies Of Johnson & Johnson
    Principal Scientist
    The Janssen Pharmaceutical Companies Of Johnson & Johnson Oct 2020 - Dec 2021
    Raritan, New Jersey, Us
    Working on translational science in the immunology therapeutic area for autoantibody-driven diseases. Identifying biomarkers and developing assays to understand aspects of disease and treatment.
  • Momenta Pharmaceuticals
    Principal Scientist
    Momenta Pharmaceuticals Dec 2018 - Oct 2020
    Cambridge, Massachusetts, Us
  • Momenta Pharmaceuticals
    Senior Scientist
    Momenta Pharmaceuticals Nov 2006 - Oct 2020
    Cambridge, Massachusetts, Us
    Disease BiologyUsing surface plasmon resonance to evaluate protein/polysaccharide interactions, antibody affinity and immunogenicity.Gene expression studies using RT-PCR and associated analysis techniques
  • Broad Institute Of Mit And Harvard
    Research Associate Ii
    Broad Institute Of Mit And Harvard Dec 2004 - Nov 2006
    Cambridge, Ma, Us
    Design and conduct secondary biochemical assays to confirm small molecule binding to protein targets using primarily the Biacore S51 surface plasmon resonance instrument. Other types of assays include human serum albumin binding, equilibrium dissociation constant (KD) measurement for small molecules binding to proteins.
  • Entegris
    Applications Engineer Ii
    Entegris Mar 2001 - Apr 2004
    Billerica, Ma, Us
    Supported Photochemical Filtration and Wet Etch and Cleans Filtration business areas. Designed testing for new products, solved application related problems with existing products and provided technical data on the effacacy of filtration and ozone contacting products to promote their use in new areas.
  • Millennium Pharmaceuticals
    Intern
    Millennium Pharmaceuticals Jun 1999 - Mar 2001
    Cambridge, Ma, Us
    Developed test methods for ensuring the accuracy and repeatability of automated pipettors used in high throughput screening (HTS). Assisted in building and maintaining robotic systems.
  • Charles Stark Draper Laboratory
    Intern
    Charles Stark Draper Laboratory Jun 2000 - Dec 2000
    Cambridge, Ma, Us
    As a member of the Chem/Bio group I worked with flexural plate wave (FPW) biological and chemical sensors. I tested the efficacy of polymer coating and protein binding to the sensor’s gold plated surface.

Jay Duffner Skills

Biotechnology Assay Development Protein Chemistry Elisa Molecular Biology Cell Qpcr Drug Discovery High Throughput Screening Rt Pcr R Statistics Oncology Lifesciences Microarray Immunoassays Laboratory Automation Project Management Life Sciences Cell Biology Real Time Polymerase Chain Reaction Sharepoint Linear Regression R Package Development Surface Plasmon Resonance Crispr Principal Component Analysis Microarray Analysis Electronic Laboratory Notebook

Jay Duffner Education Details

  • Tufts University
    Tufts University
    Chemical Engineering
  • Northeastern University
    Northeastern University
    Pharmaceutical Biotechnology
  • Boston University
    Boston University
    Management

Frequently Asked Questions about Jay Duffner

What company does Jay Duffner work for?

Jay Duffner works for Frontier Medicines

What is Jay Duffner's role at the current company?

Jay Duffner's current role is Associate Director of Discovery Biology.

What is Jay Duffner's email address?

Jay Duffner's email address is jd****@****rma.com

What is Jay Duffner's direct phone number?

Jay Duffner's direct phone number is +161728*****

What schools did Jay Duffner attend?

Jay Duffner attended Tufts University, Northeastern University, Boston University.

What are some of Jay Duffner's interests?

Jay Duffner has interest in Hiking, Soccer, Science History, Cycling.

What skills is Jay Duffner known for?

Jay Duffner has skills like Biotechnology, Assay Development, Protein Chemistry, Elisa, Molecular Biology, Cell, Qpcr, Drug Discovery, High Throughput Screening, Rt Pcr, R, Statistics.

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