Jay Tang Email & Phone Number

Los Angeles, Ca, Us

Tokyo, Jp

Oversee a team of Computational Leaders, who are responsible for the design and execution of computational biomarker strategies in gastrointestinal and inflammation therapeutic area• As the Computational Leader, develop and implement innovative multi-omics based biomarker strategies for clinical program development, including emerging RNAi, microbiome and cell therapy modalities. • Design, develop and validate gene signature panels for patient enrichment, selection, and stratification in clinical trials • Create and execute computational strategies for drug repurposing and indication expansion in late-stage clinical programs, such as Zasocitinib and Darvadstrocel franchises • In-silico predictions of drug combination efficacy and safety during lifecycle management (LCM) for Vedolizumab franchise • Serves as a subject matter expert (SME) for regulatory communications, industry consortiums, business development diligence teams.

Los Angeles, Ca, Us

Oversew the R&D, operations, and fulfilling diverse functions, • Directed the evaluation, acquisition, and implementation of cutting-edge genomics technologies and bioinformatics solutions. For instance, the team achieved the distinction of being the 1st certified single-cell transcriptome service provider in United States, and early adopter/key opinion leaders in spatial transcriptomics. • Established and fostered collaborations in genomics technologies and data analysis with industry and academic partners. Served as an ambassador at large for scientific consortiums as well as local research communities. Educated and shared domain expertise to support translational applications of genomics and bioinformatics as a scientific leader.• Initiated and developed institutional data strategies and informatics resourcing across multiple departments. Co-managed data infrastructure for large multi-omics datasets in clinical research studies on campus. • Responsible for administrative, operational, and fiscal planning, including budgeting, pricing, marketing, etc. As a result, the core facility quadrupled its revenue within three years.

Los Angeles, Ca, Us

Diseases-associated biomarkers identification via multi-omics data analysis, • Profiled the bacterial and fungal microbiome in gastrointestinal disorders such as IBD, IBS, and Hirschsprung, as well as in cancer patients. Notably, I established a fungal reference database for gastrointestinal fungal ITS mycobiome profiling.• Profiled clonal evolution through single-cell transcriptome analysis in lung airway epithelial progenitors from Idiopathic Pulmonary Fibrosis (IPF) patients, as well as in limbal iPSC from Type 2 Diabetic patients • Biomarker discovery via integrated analysis of transcriptome and epigenomics data for cancer patient subgrouping analysis, specifically in renal cell carcinoma and prostate cancer patients• Established an automation portal for NGS data storage, management, processing, analysis, and visualization.