John Biggins Email & Phone Number

Oceanside, New York, United States

Greater New York City Area

Greater New York City Area

LifeMine Therapeutics is pioneering a genomically-enabled drug discovery approach, integrating advanced life science and computational technologies to elucidate human biology and create sophisticated therapeutics that attack the fundamental drivers of serious human diseases. LifeMine is accessing new drug modalities by conducting the first industrial-scale operation exploiting small molecule evolution in fungi to discover game-changing therapeutics. With operations in Cambridge MA and Manhattan, LifeMine brings a unique global approach to its revolutionary scientific and medical mission.

Hempstead, Ny

Greater New York City Area

• Conducted industrial-scale survey of worldwide soil-derived metagenomes for mining the biosynthetic systems of potential next-generation cancer and antiinfective drugs• Managed and conducted independently funded research project for bioterrorism and emerging infectious threats (via NIH-established Regional Centers of Excellence; RCE)• Discovered and characterized novel cellular chemistry within hypervirulent bacterial pathogens that are required for initiating and propagating lethal infections (virulence factors)• Developed translational drug discovery platform based on inhibition of these virulence factors• Collaborated with three BSL3+ rated animal research centers • Presented data at biannual RCE regional and national conferences • Delivered yearly projections on time and on budget• Mentored and trained five students/technicians under my direct supervision• Wrote and prepared two major NIH grants • Lead author of four high-profile research manuscripts

Newark, De

• Managed and budgeted independent research project (including salary) from awarded funds, removing cost burden from University resources• Developed unique chemical biology method to understanding cryptic hormone signaling in metabolic diseases relating to cancer (breast, prostate) and metabolic disease.• Developed protocol to probe neuron axon guidance and plasticity in a spatially- and temporally-focused manner via targeted gene expression through a photo-caged hormonal activation system.• Wrote and prepared three manuscriptsAwards and Honors: • 2005-2007: Damon Runyon Cancer Research Foundation ~ Robert Black Fellowship; $134,000• 2005: PhRMA Foundation ~ Postdoctoral Fellowship in Pharmacology/Toxicology (personally declined for Damon Runyon fellowship); $105,000

Greater New York City Area

• Presented data at annual national professional conferences (e.g. American Chemical Society, American Association for Cancer Research) • Mentored and taught New York State high school science teachers new and advanced biomedical research techniques to for innovating school curriculum (via Cornell Institute for Biology Teachers) • Mentored New York City elementary school students in developing and carrying out a protocol for scientific exploration (Cornell Science Challenge)• Lead author and co-author of twelve high-profile manuscripts Awards and Honors: 2 competitive fellowships and 4 research awards• 2004: Julian R. Rachele Research Prize; $1000 • 2003: Gordon Research Conference; Bioorganic Chemistry ~ Pfizer Prize; $500 • 2001-2002: Pharmaceutical Research and Manufacturers of America (PhRMA) Foundation ~ Fellowship for Advanced Predoctoral Training in Pharmacology and Toxicology;$25,000• 2001: Cornell University ~ Vincent duVigneaud Prize; $1000• Frank Lappin Horsfall, Jr. Fellowship; $8000 • Cornell University ~ Vincent duVigneaud Prize; $1000

Bronx, Ny

• Taught six college level chemistry courses (e.g. General Chemistry, Organic Chemistry, Forensic Chemistry, Food Chemistry)• Managed funding, maintenance, and supplies for the Organic Chemistry department.• Conducted independent synthetic chemistry research• FCC-licensed radio engineer and part-time radio host/DJ (WFUV 90.7 FM)• New York State licenced Emergency Medical Technician-D (Fordham University Emergency Medical Services)

Phd, Pharmacology

Activities and Societies: Cornell Institute for Biology Teachers (CIBT) Cornell Science ChallengeChemical Biology; Bioorganic Chemistry.

Bs Chemistry; Bs Psychology, Organic Chemistry

Activities and Societies: Honors Society ~ Psychology. HELPLINE peer counseling.Student Research Assistant; Organic Chemistry NY State.