Phd Candidate
Wageningen, Gelderland, Nederland
During my PhD I worked on both fundamental (WU) and applied science (TNO) related to muscle-aging. At Wageningen University, I combined (among others) RNA-sequencing generated data with immunohistochemistry to map the changes that occur within muscle tissue during aging in humans. At TNO, using the same techniques, I assessed the translational value of various models for human-muscle aging. In addition, I tested potential anti-muscle atrophy compounds on these models and results were compared to those originating from human studies. Lastly, using a data-driven in-silico prediction approach, we identified potential blood-based biomarkers for the early identification of frailty in humans.