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Jean-Claude Chèvre, Phd Email & Phone Number
Clinical Data Manager
at
AP-HP, Assistance Publique - Hôpitaux de Paris
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Role
Clinical Data Manager
Location
Greater Lille Metropolitan Area, France
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Jean-Claude Chèvre, Phd is listed as Clinical Data Manager at AP-HP, Assistance Publique - Hôpitaux de Paris, a with 1167 employees, based in Greater Lille Metropolitan Area, France. AeroLeads shows a matched LinkedIn profile for Jean-Claude Chèvre, Phd.
Jean-Claude Chèvre, Phd previously worked as Biologist engineer in data analysis at Chru De Nancy and Biologist engineer in data analysis at Inserm. Jean-Claude Chèvre, Phd holds Doctor Of Philosophy (Ph.D.), Human Molecular Genetics, With Highest Honour (Tb) from Université Pierre Et Marie Curie (Paris Vi).
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AP-HP, Assistance Publique - Hôpitaux de Paris
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Profile bio
About Jean-Claude Chèvre, Phd
17 years experience in human molecular genetics and genomics of type 2 diabetes and obesity. 2+ years experience in bioinformatics. 2+ year in clinical data management.PhD in human molecular genetics with a background in biochemistry, developmental biology, molecular biology, and genomes organization, and complementary & continuous education & experience in bioinformatics & statistics, and clinical data management (Linux, Shell Bash, R/RStudio, CRF, aCRF, eCRF, Clinfile G-ERDC/ERDC®, SAS®, Ennov Clinical®, Telemedecine CleanWeb®).Particularly interested in translational research and biocuration, especially in computational approaches for the annotation, interpretation, prioritization and prediction of variants and genes in association with diseases/phenotypes, biological networks and pathways, metabolites and drugs, more generally in “big data to knowledge” for precision medicine and knownledge integration for biology.21 scientific papers:2 Nature, 3 Nature Genetics, 2 Human Molecular Genetics, 2 JCI, 1 Plos Genetics, 5 Diabetes, 2 Diabetologia, 1 European Journal of Endocrinology, 1 Human Mutation, 1 Frontiers in immunology, 1 JCEM(for more details see Google Scholar link below) .h-index: 18, RG score: 31.54
Listed skills include Genomics, Sequencing, Molecular Biology, Genetics, and 35 others.
Current workplace
Jean-Claude Chèvre, Phd's current company
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Ap-Hp, Assistance Publique - Hôpitaux De Paris
9 roles
Jean-Claude Chèvre, Phd work experience
A career timeline built from the work history available for this profile.
Clinical Data Manager
• Case Report Form (CRF) draft reviewing• eCRF testing (CleanWeb)• Queries programming (Excel, SAS)• Data Validation Plan (DVP) writing• Queries feedback processing (Excel, SAS)• Data / Blind review and data management report (Excel, SAS, ppt and word)• Database preparation and transfer for statistical analyses (Excel, SAS)
Biologist Engineer In Data Analysis
CNRS UMR 7365 IMoPA Ingénierie cellulaire - Immunothérapie cellulaire et approches translationnelles CeCiTa Cell Engineering, Cellular Immunotherapy and Translational Approaches (Pr. Marie-Thérèse RUBIO)• Flow cytometry data analyses (bibliography on bioinformatics tools, data cleaning, flowCore, flowClean)• Transcriptomics data analyses (Reactome, GeneOntology, KEGG, bibliography on Tregs)• Continuing self-learning: linux shell bash, RStudio/RPublication: Frontiers in immunology 2020/11 (see Google Scholar Link below for more details)
Jan 2020 - Apr 2020
Biologist Engineer In Data Analysis
Inserm U1256 ex. U954 n-GERE Nutrition-Genetics and Exposure to Environmental Risks (Directeur: Pr. Jean-Louis GUEANT)• Epigenome-Wide Association Studies (EWAS) with children outcomes in placenta of mothers (R package: meffil).• EWAS/DMPs and DMRs analyses with fibrosis in liver of morbidly obese patients (R package: minfi, meffil,DMRcate)• Continuing self-learning: linux shell bash, RStudio/R
Jan 2019 - Dec 2019
Senior Postdoctoral Researcher
Inserm U1256 ex. U954 n-GERE Nutrition-Genetics and Exposure to Environmental Risks (Directeur: Pr. Jean-Louis GUEANT)• frequent and rare BMi-associated variants Polygenic/Genetic Risk Scores (PRS/GRS) analyses in morbidly obese patients undergoing bariatric surgery (exome chip QC with GenomeStudio and plink; variants selection with Linux Bash, spreadsheet, Snipa, Variant Effect Predictor, PredictSNP2; statistical analyses with R: t-test, multiple linear regression)• Continuing self-learning: Linux Shell Bash, RPublication: The Journal of Clinical Endocrinology & Metabolism 2021/10 (see Google Scholar Link below for more details)
Jan 2018 - Dec 2018
Stay-At-Home Dad Jobseeker And Volunteer
• Job hunting, applications (n=90) and interviews (n=12)• Online self-learning: Completed: ▪ 'Write your first Java program' from CNAM on fun-mooc , score: 100% .• Completed 9 months professional course: Bio-Informatics certificate at CNAM, Paris (see below Education for more details)• Volunteering (12 hours p.w.): tutoring in mathematics, life (biology) and Earth (geology) sciences, at La Clé, Club Léo Lagrange, at Association pour le soutien scolaire and at Maison de quartier les Moulins; tutoring in computer basics at Solidarité Informatique and Club Léo Lagrange; community manager at Solidarité Informatique. (see below Volunteer for more details)• Sciences private lessons (2 hours p.w.)• At-home husband and dad (cooking, housekeeping, food shopping, parenting and looking after my youngest 6-13 yo daughter, ...; ~ 20 hours p.w.)
Jan 2011 - Dec 2017
Senior Postdoctoral Researcher
• Gene-centric whole genome integration of genetic, genomic and functional heterogeneous data for type 2 diabetes and obesity for:- gene prioritization from whole genome differential expression, association (WGAS), or CNVs studies; - candidate genes lists for sequencing; - SNPs and genes functional annotation (FTO, MTNR1B, HK1). Unpublished (see attached presentation for further details). Would like to have the opportunity to pursue in such field.• "Type 2 diabetes or obesity associated genes' genetic, genomic and functional studies (CNR1, ANGPTLs, C1orf32, FTO).Publications: Nature 2010/02; Diabetes 2009/11; Nature Genetics 2009/01, 2008/12, 2007/05; Human Molecular Genetics 2008/07 (see Google Scholar Link below for more details)Reason for leaving : reached the 6 years limit under contract CNRS's rule. (http://goo.gl/cLP8G6)
Mar 2005 - Dec 2010
Postdoctoral Researcher
• Positional cloning – in vitro and in silico genomic and transcriptional mapping of a fasting and in response to glucose hyperglycemia quantitative trait locus (QTL) in a type 2 diabetes obese mouse model. Mutation detection by sequencing and transcripts' quantitative expression study by qPCR for type 2 diabetes susceptiblity gene discovery.Publication: PLoS Genetics 2008/07 (see Google Scholar Link below for more details)Reason for leaving : family reason
Feb 2000 - Feb 2005
Phd Fellow
• "Genetic Study of the Maturity-Onset Diabetes of the Young (MODY)", CNRS UPRESA 8090, IBL, Lille; awarded with high honors on January 10, 2000.Publications: Diabetes 2003/03, 2000/02, 1998/05, 1997/12; European Journal of Endocrinology 2000/04; Human Mutation 2000/02; Journal of Clinical Investigation 1999/11, 1998/02; Diabetologia 1999/03, 1998/08; Human Molecular Genetics 1997/04; Nature 1996/12 (see Google Scholar Link below for more details)
Mar 1996 - Jan 2000
9 education records
Jean-Claude Chèvre, Phd education
Doctor Of Philosophy (Ph.D.), Human Molecular Genetics, With Highest Honour (Tb)
Certificat De Formation Professionnelle Au Métier De Data Manager En Recherche Clinique, Clinical Data Management, Mention Ab (12.7)
Https://Www.Linkedin.Com/Company/Formatis
Certificate Of Proficiency In Bioinformatics, Bioinformatics, With Honours
University Diploma Of Biostatistics Applied To Clinical Research And Epidemiology, Biostatistics
Master'S Degree (Msc), Cell/Cellular And Molecular Biology, With Highest Honour (Tb)
Military Service
Central Direction Of Medical Army, Invalides, Paris
Master'S Degree, Biochemistry, Genetics, And Organic Chemistry, With Honours (Ab)
Bachelor'S Degree, Biochemistry, Genetics, And Organic Chemistry
Baccalaureate, Sciences
FAQ
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What company does Jean-Claude Chèvre, Phd work for?
Jean-Claude Chèvre, Phd works for AP-HP, Assistance Publique - Hôpitaux de Paris.
What is Jean-Claude Chèvre, Phd's role at AP-HP, Assistance Publique - Hôpitaux de Paris?
Jean-Claude Chèvre, Phd is listed as Clinical Data Manager at AP-HP, Assistance Publique - Hôpitaux de Paris.
Where is Jean-Claude Chèvre, Phd based?
Jean-Claude Chèvre, Phd is based in Greater Lille Metropolitan Area, France while working with AP-HP, Assistance Publique - Hôpitaux de Paris.
What companies has Jean-Claude Chèvre, Phd worked for?
Jean-Claude Chèvre, Phd has worked for Ap-Hp, Assistance Publique - Hôpitaux De Paris, Chru De Nancy, Inserm, Université De Lorraine, and Cnrs Umr8199 (Directeur : Pr. Philippe Froguel).
How can I contact Jean-Claude Chèvre, Phd?
You can use AeroLeads to view verified contact signals for Jean-Claude Chèvre, Phd at AP-HP, Assistance Publique - Hôpitaux de Paris, including work email, phone, and LinkedIn data when available.
What schools did Jean-Claude Chèvre, Phd attend?
Jean-Claude Chèvre, Phd holds Doctor Of Philosophy (Ph.D.), Human Molecular Genetics, With Highest Honour (Tb) from Université Pierre Et Marie Curie (Paris Vi).
What skills is Jean-Claude Chèvre, Phd known for?
Jean-Claude Chèvre, Phd is listed with skills including Genomics, Sequencing, Molecular Biology, Genetics, Sequence Analysis, Dna Sequencing, Dna, and Lifesciences.
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