Jee Look Email & Phone Number

Boyds, MD, US

Gaithersburg, Maryland, US

• Comprehensive CMC Strategy: Provided comprehensive CMC strategy from pre-clinical through licensure to post-marketing for Internal programs and CDMO client. Coordinated Drug Product Development Plans with.
• Team Building and Integration: Established a biologics drug product development team from scratch, capable of supporting CDMO clients and internal programs. Developed a business model to integrate Development team into.
• Funding Acquisition and Milestone Achievement: Secured $20 million in BARDA funding for the development of AV7909 commercial manufacturing process (Phase 3 PPQ) and $29 million in NIH funding for developing novel dry.
• Advanced Formulation Technologies: Developed in-house dry stabilization technologies incorporating state-of-the-art lyophilization techniques (MicroFD, Revo® Pro, LyoStar 3-TDLAS), spray drying, and foam drying..
• Aseptic Formulation/Fill/Finish Processes: Developed novel nanoparticle aseptic manufacturing processes for mRNA-LNP, siRNA-peptide, mAb, ADC and suspension drug. Managed these processes from pre-clinical to early.
• Drug Development Programs: Advanced 15 discovery programs to tox, phase I/II/III, including siRNA-peptide, Sudan mAb (CA45/FVM04), rPA vaccine, live virus vaccines (MVA-TB/-Flu/-Ebola [Phase I/II], VSV Lassa (Phase I)..

• Transcutaneous Immunization Development: Led transcutaneous immunization drug delivery development including patch, micro-needle, micro-injector: ETEC vaccine (Ph I-III, & PPQ), Influenza (Ph 1), C. Difficile (Ph 1).
• Patch Manufacturing Technology: Developed first of the kind GMP patch manufacturing technology for transcutaneous vaccines from proof of concept to Phase 3 (PPQ), focusing on dose sparing and traveler diarrhea ETEC.
• Immune modulator formulation: Invented novel nano particle delivery technology to modulate immune response of biologics, “IC31 Nanoparticle for adjuvant” (US Patent: 9,248,180 B2).

• Pneumococcal Glycoconjugate Vaccine Development: Developed the 2nd generation Pneumococcal glycoconjugate vaccine (13V Prevnar®) formulation and aseptic (F/F/F) manufacturing processes utilizing pre-filled syringes..
• Aseptic Live Virus Vaccine Manufacturing (2nd Gen FluMist®): Developed aseptic live virus commercial scale F/F/F processes for intra-nasal Cold Adapted live Influenza Virus Vaccine (2nd generation FluMist®) and.
• Innovative Live Virus Vaccine Formulations: Invented a stabilized intra-nasal vaccine for Cold Adapted live virus RSV/PIV (US Patent 8,603,796 B2). Developed formulations for bacterial Meningococcal B (MnB) and Group A.

• New Technology Development for OTC Products: Engaged in the development of new technologies for over the counter (OTC) products. Invented a fast-dissolving tablet technology for small molecular drugs using a.
• Consumer Study: Created various conceptual products for marketing evaluation, including an edible film-containing drug, gel cooling patches for hemorrhoids, and Chapstick. Conducted cost and financial analysis for new.
• Technology Transfer Management: Managed third-party technology transfers to enhance the company’s in-house manufacturing capabilities for tablet technology in spray drying, twin-screw extrusion, supercritical fluid.

Cincinnati, Ohio, US

• Nanoparticle Capability Development for Cosmetic: Built new in-house nanoparticle capabilities in dry/wet milling, coating, and encapsulation for cosmetic products. Invented a novel nanoparticle processing technology.
• Consumer Study: Created various conceptual products for marketing evaluation, including focus group product assessments in a global market setting.

Oak Ridge, TN, US

• Advanced Materials for Semiconductors: Conducted nanoparticle research for advanced materials for semiconductors. Invented hollow nanoparticle manufacturing technology for use in multilayer semiconductor chips (US.
• Nanoparticle Separation Research: Performed separation research for nanoparticles using electrical fields. Submitted four disclosures to the US Department of Energy (DOE).

• Nanoparticle Synthesis Lab Setup: Led the production of uniform powders for advanced materials applications.Established a sol-gel powder synthesis laboratory.
• Semiconductor Substrate Research: Successfully identified factors causing inconsistent suspension stability in multilayer semiconductor substrates used in supercomputer chips. Resulted in a processing patent.

Ph.D, Chemical Engineering (Nanotechnology/Material Science/Colloidal Science)

Master Of Science - Ms, Semiconductor Manufacturing Technology (Plasma Etching Of Silicon Wafer)

Mba, Finance

Bsc, Chemical Engineering