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Broad scientific background in autoimmunity, inflammation, osteoarthritis, pharmacology, coagulation disorders, cardiovascular disease, and rare genetic disorders.Extensive experience with small molecules, biologics, nucleic acid, and gene therapy-based therapeutic research and developmentSuccessful leader of cross-functional project teams who has transitioned drug candidates from discovery research to clinical development.Experienced in target discovery, portfolio analysis, competitive intelligence, and in-licensing evaluations.Skilled manager of alliances with clinical consultants, contract research organizations, and academic laboratories.Expertise in assay development and biomarker identification from in vitro through in vivo proof-of-concept studiesClients Past and PresentAmbrx, Inc., San Diego, CAShire, Human Genetic Therapies, Lexington, MABlend Therapeutics Inc., Watertown, MAFlagship Ventures, Cambridge, MANimbus Discovery, Cambridge, MAAtlas Ventures, Cambridge, MASynageva, Lexington, MAJ&J Innovation Center, Cambridge, MASR-One, Cambridge, MASynLogic, Cambridge, MA5AM Ventures, Boston, MASkylarkBio, Cambridge, MAEnsoma, Inc, Boston, MAWyss Institute Boston, MAExo Therapeutics, Watertown, MAHomology Medicines Bedford, MARecardia Therapeutics, Palo Alto, CASpecialties: AutoimmunitymRNA TherapeuticsRare Genetic DiseasesInflammationPharmacologyOsteoarthritisLipid MetabolismCardiovascular and Metabolic DiseaseReceptor-Ligand Interactions
Halide Biologics, Inc.
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Chief Executive OfficerHalide Biologics, Inc. Oct 2023 - Present
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Founder/PartnerStellar Research And Development Llc Jan 2020 - PresentExperienced consultant specializing in strategic evaluation of new therapeutic opportunities, target identification, in-licensing candidates, and biologic product development including target market, strategic target, and target product profiles. Small molecules, biologics, and nucleic acid-based therapies.Extensive expertise in assay development and in vivo animal models of human disease. Clients over the past year include Ensoma, Inc (2020-present), SkylarkBio (2021-present) and the Wyss Institute (2021).
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Chief Scientific OfficerRecardia Therapeutics, Inc Jan 2020 - Dec 2023
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Senior Director, External SciencesHomology Medicines Inc. Jan 2016 - Jan 2020Head of Discovery Biology as part of the 5AM Ventures seed team that founded Homology Medicines. Inc.Key member of seed team that secured seed financing and a $43.5M Series A
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Founder/PartnerStellar Research And Development, Llc Nov 2013 - Jan 2016Experienced consultant specializing in strategic evaluation of new therapeutic opportunities, target identification, in-licensing candidates, and biologic product development including target market, strategic target, and target product profiles. Small molecules, biologics, and nucleic acid-based therapies.Extensive expertise in assay development and in vivo animal models of human disease.
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Chief Executive OfficerAvastus Preclinical Services Llc Jan 2015 - Jun 2015Consulting CEO of contract research organization specializing in oncology, infectious disease, immunology, and PK/PD models of human disease. Vivarium Services division supplies husbandry and lab/vivarium space for biotech/pharma companies on short- or long-term basis.
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Chief Scientific OfficerAvastus Preclinical Services Llc Jan 2014 - Jan 2015Consulting CSO of contract research organization specializing in oncology, infectious disease, immunology, and PK/PD models of human disease. Vivarium Services division supplies husbandry and lab/vivarium space for biotech/pharma companies on short- or long-term basis.
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Senior DirectorModerna Therapeutics Aug 2012 - Nov 2013Cambridge, Massachusetts, UsPre-Clinical Pharmacology,Head, Rare Disease Research -
FounderEllsworth Biotech/Pharma Consulting May 2011 - Aug 2012Experienced consultant specializing in strategic evaluation of new therapeutic opportunities, target identification, in-licensing candidates, and biologic product development including target market, strategic target, and target product profiles.
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Senior Director, New OpportunitiesEleven Biotherapeutics Nov 2010 - Mar 2011Developed new project initiatives, target market and target product profiles for therapeutic candidates and established extensive network of clinical consultants.
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Director, Target Validation And RealizationAmbrx Mar 2009 - Sep 2009Led effort to identify new therapeutic targets for pharmacokinetic enhancement
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Principal ScientistZymogenetics 1997 - 2009Department of Immunology: Leader of cross-functional project team for the Fc Receptor Antagonist project targeting inflammation and autoimmune diseaseDepartment of In Vitro Biology: Led cross-functional project team that established the biological /clinical utility of FGF18 in osteoarthritis and stroke. Scientific lead for FGF18 partnering.In-licensing evaluations
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Senior ScientistCv Therapeutics May 1993 - May 1997Palo Alto, Ca, UsGroup Leader for effort to establish the mechanism of cholesterol absorption by intestinal cells in culture and developed small molecule inhibitors of the process. -
Staff ScientistPalo Alto Medical Foundation 1989 - 1993Mountain View, Ca, UsLab Head for group studying the regulation of hepatic LDL receptor gene transcription. -
PostdocStanford University Medical Center 1982 - 1986Palo Alto, California, Us
Jeff Ellsworth, Ph.D. Skills
Jeff Ellsworth, Ph.D. Education Details
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Stanford UniversityDept Of Biological Sciences -
Stanford University School Of MedicineLipid Metabolism
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University Of Cincinnati College Of MedicinePharmacology And Cell Biophysics
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Indiana University BloomingtonChemistry
Frequently Asked Questions about Jeff Ellsworth, Ph.D.
What company does Jeff Ellsworth, Ph.D. work for?
Jeff Ellsworth, Ph.D. works for Halide Biologics, Inc.
What is Jeff Ellsworth, Ph.D.'s role at the current company?
Jeff Ellsworth, Ph.D.'s current role is Founder/Partner at Stellar Research and Development LLC.
What is Jeff Ellsworth, Ph.D.'s email address?
Jeff Ellsworth, Ph.D.'s email address is je****@****ail.com
What is Jeff Ellsworth, Ph.D.'s direct phone number?
Jeff Ellsworth, Ph.D.'s direct phone number is (617) 714*****
What schools did Jeff Ellsworth, Ph.D. attend?
Jeff Ellsworth, Ph.D. attended Stanford University, Stanford University School Of Medicine, University Of Cincinnati College Of Medicine, Indiana University Bloomington.
What skills is Jeff Ellsworth, Ph.D. known for?
Jeff Ellsworth, Ph.D. has skills like Pharmacology, Inflammation, Biotechnology, Competitive Intelligence, Autoimmunity, In Vivo, Project Teams, Cell, Elisa, Lipid Metabolism, Pharmaceutical Research, Team Leadership.
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