Jeff Schreier Email & Phone Number

Huntsville, Alabama Area

United States

Directs all manufacturing effortsWrote necessary document for GMP compliant production

Led a team of 7 scientist with multiple disciplines Managed & implemented wide range of cost & productivity optimization projects: development of new raw materials, established new analytical testing procedures, and set specificationReduced failed batches from 7 to 2%Reduced cycle times by as much as 60% for unit operations and 10% for overall processDeveloped, implemented and validated a new cleaning procedure for the multipurpose manufacturing area.The new cleaning procedure reduced cleaning waste by 60%New cleaning procedure was extended to the second newly constructed manufacturing area.Provided significant contributions to the design of multipurpose production suite.Design contributions improved the operational flow pattern and isolated solids handling from wet chemistry for potential potent compound handlingConstruction changes simplified cleaning and unit operations

Assembled and tested equipment; wrote and executed procedures to safely produce potent compounds in-house Reduced project life cycle by 10 monthsIn-house production reduced project cost by 300KImplemented new raw material handling procedures Received the Nektar Star award for improving the safety of plant operationsWrote technical transfer document to move processes off site

Manager of the Potent Compound Manufacturing Suite, PCMS1Contributed to the design and supervised the construction of the suiteWrote and executed qualification protocols related to potent compound manufacturingDeveloped and documented the standard operating procedures that governed the operation of the production suiteProject Manager for production in PCMS1, pilot plant, and production plantsSuccessfully delivered every product with the desired quantity and qualityCompleted 10 projects per year ranging from single laboratory step to 12 step production of bulk drug substance

Responsible for daily operations in the pilot plant; process development, troubleshooting, and rework proceduresWrote and executed qualification documents for the reactors and dryersDeveloped new routes to potential API'sManaged the clinical supply laboratoriesReduced production times by installing larger fixed reactorsHired staff and implemented shifts for 24h production Responsible for scale-up and production of multi-step synthetic routes to pharmaceutical API's

Process chemist responsible for improvements to a series of flame retardants Converted a batch process to a continuous process, tripling capacity Improved the yield of a commodity chemical by >1% and improved assay from 97 to 100%Conducted operations at lab, pilot and plant scale production; Five pilot productions and two production plant start-ups

Ph.D, Chemistry

B.S, Chemistry