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Jeff Lock is listed as Project Scientist at University of California, Irvine based in Aliso Viejo, California, United States. AeroLeads shows a matched LinkedIn profile for Jeff Lock.
Jeff Lock previously worked as Project Scientist at Uc Irvine and Postdoctoral Scientist at Uc Irvine. Jeff Lock holds Doctor Of Philosophy - Phd, Physiology And Biophysics from Case Western Reserve University.
I am a cell physiologist with a problem solving mentality and a passion for scientific discovery and innovation. With over 17 years of hands on experience conducting molecular, cellular, biochemical, and biophysical studies in cultured cells and cell-free systems, I have a documented history of developing and applying in vitro assays to address technically challenging and complex biological questions.
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Department Of Neuorbiology And Behavior
Led research initiatives employing live-cell, high content fluorescence imaging of cultured cells (wide-field, TIRF, light-sheet microscopy), advanced image analysis procedures, and in vitro genetic models which achieved mechanistic insights into inositol trisphosphate (IP3) receptor (IP3R) mediated Ca2+ signaling in mammalian cellsManaged cell culture.
Department Of Neurobiology And Behavior
Independently managed experimental studies using wide-field, TIRF, and super-resolution microscopy with msec resolution and nm precision to resolve the biophysical properties and spatial distributions of IP3Rs in cultured cells Designed and executed a screen of synthetic and genetically encoded fluorescent Ca2+ indicators that established optimal probes.
Department Of Physiology And Biophysics
Carried out a multifaceted research project incorporating fluorescence microscopy and protein biochemistry to investigate the effects of oxidative stress on vascular endothelial cells, leading to the publication of 2 first author journal articles and helping to secure $788K in grant fundingDiscovered a novel post-translational modification.
Department Of Neurosciences
Conducted stereotactic guided survival surgeries, IHC, IF, ELISA, cell apoptosis assays, and cell proliferation assays to investigate glioblastoma cell migration in rodents in vivoDeveloped a 3D slice culture model for fluorescence monitoring of tumor cell migration in situ, reducing project costs and enabling mechanistic studies unfeasible in.
Boston, Massachusetts, United States
Provided personalized and group exercise prescription for healthy and injured clients.
Department Of Noninvasive Cardiology And Imaging
Collected patient history, prepped patients for exams, and assisted in electrocardiogram, echo-cardiogram, and nuclear imaging tests by monitoring for atrial and ventricular arrhythmias as well as other cardiac disturbances.
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Jeff Lock is listed as Project Scientist at University of California, Irvine.
Jeff Lock is based in Aliso Viejo, California, United States.
Jeff Lock has worked for Uc Irvine, Case Western Reserve University, Wellbridge Center For Health And Fitness, and Beth Israel Deaconess Medical Center.
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Jeff Lock holds Doctor Of Philosophy - Phd, Physiology And Biophysics from Case Western Reserve University.
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