 Responsible for the overall management of laboratory studies, training, supervise, and performance reviews: biopharmaceutical (e.g., biosimilar antibodies, new proteins, antisense oligonucleotides, antibody-drug conjugates drug-to-antibody ratio, etc.) characterization, drug metabolic identification/profiling/confirmation, and drug impurity identification/profiling/ confirmation using high resolution mass spectrometry coupled with liquid chromatography

 Responsible for the overall management of laboratory studies, training, supervise, and performance reviews: pharmaceutical analysis (using LC-MS/MS MRM) and quality assurance of bioanalytical center

 Responsible for the overall management of laboratory studies, training, supervise, and performance reviews: pharmaceutical analysis (using LC-MS/MS MRM and ELISA), quality assurance, project management, and clinical research

 Responsible for the overall conduct of a laboratory study as defined by the Company SOPs Write and review final reports Ensure the proper maintenance of daily operation records Responsible for training junior scientists Supervise junior scientists in daily operations Participate in performance reviews for junior scientists

The analytical projects were performed based on GLP/GCP compliances (KFDA).Research theme: Small Molecule Mass Spectrometry and Proteomics Mass Spectrometry Development and validation of LC-MS/MS-based analytical methods for Pharmacokinetics and Diagnostics Method development for Absolute/targeted quantitative proteomicsManagement Responsible for training junior scientists Supervise junior scientists in daily operations Participate in performance reviews for junior scientistsUsed LC-MS/MS LC: Waters UPLC and Agilent LC MS: AB Sciex (5500QTrap and API-4000), Agilent (QQQ-6460, QQQ-6490 and QTOf-6520), and Waters Xevo TQ-S

Research theme: Proteomics Mass Spectrometry Global Proteomics: Post-translational modifications (e.g. acetylation, crotonylation, phosphorylation, etc) Stable isotope labeling by amino acids in cell culture (SILAC)-based quantitative proteomicsUsed LC-MS/MS LC (nano flow): Agilent LC and Eksigent LC MS: ThermoFinnigan (LTQ, LTQ-Orbitrap, and LTQ-Orbitrap-Velos)

The analytical projects were performed based on semi-GLP and GMP complianceResearch theme: Small Molecule Mass Spectrometry Development of ultra-fast LC-MS/MS bioanalytical methods for PK study in stage of drug design In vivo and in vitro drug metabolite characterization  Identification of drug substances, intermediates and impuritiesUsed LC-MS/MS LC: Waters, Agilent and Shiseido LC MS: AB Sciex (API-4000 and API-2000), Waters QTof MS and LTQ

Research theme: Proteomics Mass Spectrometry Post-translational modifications: phosphorylation and oxidation Used LC-MS/MS LC: Agilent LC  MS: Waters QTof MS and ThermoFinnigan LCQ

Research theme: Small Molecule Mass Spectrometry: Environmental Analysis of Dioxins Method development for determination of polychlorinated dibenzo-p-dioxins/furans (PCDD/Fs) in processed food salts and fly ash Played a role in the Official Recognition Team for Dioxin Analysis in the Ministry of Environment (ME) and Korea Food & Drug Administration (KFDA)Used GC-MS GC: Agilent HRGC  MS: Jeol HRMS (magnetic sector, resolution >10,000)