Jessica Salemi Email and Phone Number

Duties: customer service, stocking of shelves, computer work, printing tickets and signs, general tidying of store and displays, use of a POS system, task delegation, ordering.

Investigation of the ability of outer membrane vesicles produced by Helicobacter pylori to induce the production of interleukin-37 by gastric epithelial cellsCharacterisation of both intracellular and secreted levels of interleukin-37 after stimulation was performedMajor FindingsHelicobacter pylori-derived outer membrane vesicles were successfully shown to stimulate interleukin-37 production in gastric epithelial cellsThis increased production of interleukin-37 was only observed as a secreted formNo change in the intracellular levels of interleukin-37 was found after stimulation by Helicobacter pylori outer membrane vesicles which suggests that the increased amounts of interleukin-37 are released from the cellImprovements made to the methodology for the generation of Helicobacter pylori membrane vesicles which enabled the maximisation of yieldsAdditional improvements were made to methodology which resulted in a lower amount of membrane vesicles required to successfully stimulate gastric epithelial cells