Jesus Juárez-Brambila, Bs, Ms, Phd. Email & Phone Number

Jemison, Al, Us

United States

United States

Professional and Superior Service for the Chemical, Biotechnology & Pharmaceutical Industry.

Charles City, Iowa

Toluca Area, Mexico

Essential Duties and Job Functions:Develop analytical method validation remediation plan for the site in conjunction with Sr. ManagementManage, guide and coordinate all activities associated with Validant Analytical method validation teamsEngage with site Management & Laboratory Teams as requiredEnsure validation protocols and reports are produced in a timely fashionMonitor team progress and report to Site & Validant Management

Huntsville, Alabama Area

As Analytical Development Chemist, I applied NEKTAR analytical methods for• Routine and non routine analysis of: Raw Materials, In Process Checks, Active Pharmaceutical Ingredients, Product Development and Stability samples.• Use of Agilent and Waters instrumentation.• Use of Empower, Chemstation, and Chromeleon software for HPLC, GC, UV, IC, etc. for lab management, data acquisitions and data analysis.• Product Development Support.• Data Analyis, Troubleshooting and Complex Problem Solving• Assist with the training of analysts.• Applies cGMP, ICH and GxP on daily basis.

Naucalpan, Estado De Mexico

As method validation chemist, I revised 183 test methods used by the QC unit for analytical testing, cleaning and microbiological applications for raw materials, intermediate products, stability, bulk and final products, over the counter and prescription products. The main focuses was a detailed revision of the validation reports for current validated methods and suggest any changes needed to revalidated any method up to modern qualifications and international governing agencies regulations.• Investigation of stability failures and evaluation of analytical methods validation reports.• Worked with R&D and interfaced with the Chemists in the QC Lab.• Analyzed methods to check for accurateness and robustness. • Interacted with all levels of the organization.• Investigated stability testing methodologies in gel caps.• Wrote validation protocols for method validation.

Pelham, Alabama Usa

• Successful process development of a purine nucleoside phosphorylase (PNP) inhibitor currently in the pivotal stage of clinical trials• Tech transfer of key process steps from lab scale to pilot scale to manufacture multi-kilos of drug substance to support clinical program• Conducted spiking studies to support justification of starting materials for successful filing with the Agency. Based on this data, the Agency has accepted the two building blocks as registered GMP starting materials• Successfully synthesized multi-kilos of a broad based antiviral compound to support ongoing toxicology studies• Identification, isolation, synthesis and full analytical characterization of process impurities for ongoing drug development programs as part of the regulatory requirement • Purification of process sludge using preparatory high pressure liquid chromatography to isolate process degradents prior to manufacturing of registration lots• Responsible for analytical method development for ongoing drug development programs• Synthesized labeled drug substance to be used as internal standards (stable isotopes) for BioAnalytical department• Coordinated activities with product development group on polymorph and salt selection of potential new drug candidates• Responsible for efficient functioning and upkeep of the cGMP facility to be in compliance• Proficient in handling small to large scale reactors, Biotage columns, prep HPLC, NMR, prep LC, IR, MS and Karl-Fisher equipment• Participated as a project sub-team member on various drug development programs• Responsible for drafting technical documents and writing various sections of the IND and NDA• Trained in GMP and GLP environment and familiar with current regulatory guidance• Responsible for procurement of chemicals, reagents and maintenance of the scale-up lab

Alabaster, Alabama Usa

• Created and developed new chemical compounds for this bulk pharmaceutical company, which supplies lipid products to researchers and pharmaceutical companies worldwide• Successfully completed the synthesis and scale-up of multiple sophisticated compounds including JBT-2000, Safingol, Lipid A, synthetic ether lipids, synthetic platelet activating factor and analogs• Synthesized, purified, and performed full spectroscopic analysis on new chemical compounds • Customized new chemicals to specifications by adapting pre-existing synthesized chemicals• Developed expertise in synthesis within argon and nitrogen atmospheres, as well as extra-dry glassware• Utilized laboratory equipment and analytical instrumentation including NMR spectrometers, gas chromatography, mass spectrometers, and infrared spectrometers• Complied with cGMP and GLP regulations, SOPs, and Analytical Test Methods

Birmingham, Alabama Usa

• Taught 200-level organic chemistry courses at 17,000-student university• Supervised laboratory and teaching assistants. Performed research and applied for grants• Worked with local companies and post-graduate students on special projects and research-related activities• Participated in research involving the synthesis of new Magnetic Resonance Imaging (MRI) compounds• Synthesized innovative chemical ligands that show promising application with MRI for diagnosis of myocardial ischemic disease• Researched methods to create new compounds with greater contrast efficiency and improved bio-distribution• Performed complete synthesis, purification, and full spectroscopic analysis of new chemical compounds • Purified compounds using partition chromatography, distillation, recrystallization, thin layer chromatography, and flash chromatography • Taught courses, conducted lectures, and participated in laboratory demonstrations.

Atlanta, Georgia Usa

Explore new methodologies for pulp bleaching.

Atlanta, Georgia Usa

Organic Synthesis of Lignin related compounds

Ph.D., Synthetic Organic Chemistry

Ms, Synthetic Organic Chemistry

Bachellor In Science, Chemistry, Biology And Pharmaceutical Sciences