•Established and developed molecular engineered cells for various diseases•Developed biological assays for studying of the immune reaction, and functional response of encapsulated cells in vitro and in vivo, including western blotting, qPCR, ELISA, GSIS, IVGTT etc. •Developed novel rodent animal models for various projects•Performed preclinical studies in multiple animal models, including toxicity, efficacy, and PK/PD studies •Coordinated with therapeutic leads, prepared study design IACUC protocols, managed in vivo studies schedule•Trained personnel on in vivo studies and biological assays, and established SOPs•Managed multiple animal colonies with CRO

•Developed islets isolation and encapsulated islets and stem cells for diabetes therapy•Conducted high throughput screening of novel biomaterials and developed encapsulation approaches for cell transplantation• Animal studies in multiple models, including rodents (mice, rats) and Non-Human Primates (Monkeys)• Harvested, sectioned, stained (histological and IHC) and analyzed implants •Developed biological assays for studying of the mechanism of immune reaction in fibrotic processing, and functional response of islet cells in vitro and in vivo

cell culture