Jim Rosinski Email and Phone Number

Lead a collection of academic, CRO, and external resources to implement large scale dynamic modeling of the molecular pathways of Huntington’s disease via a virtual pharma model.Lead the creation, analysis, and modeling of large omics datasets (NGS and Proteomic based) to reconstruct the pathways of Huntington's Disease.Lead the Foundation’s proteomics platform covering both laboratory and analysis capabilitiesLead a large-scale collaboration with leading computational modeling/AI company to delve into the molecular and behavioral consequences of the HD mutation using coherent Next-Gen Sequencing datasets.

Lead disease modeling and systems biology efforts between Oncology and Translation Research Sciences at Roche

Led an integrated systems biology team; successfully designed and delivered numerous target and biomarker discovery studies.Drove the Roche in silico target discovery process by using a novel combination of bioinformatics, biostatistcs, text mining, and cheminformatics analyses. Developed technical group and grew from a small bioinfo core to into a large data mining group expanding our content area coverage to cheminformatics and to inflammatory diseases.Defined and Led projects that brought complex in silico methods to scientists desktops in conjunction with the Research Informatics groups.Informatics accomplishments included an in silico target discovery platform for Oncology, a GLP-validated analysis system for cardiac telemetry data, and a micro RNA knowledge base.Major Line management responsibility for technical personnel, analysis activities, project management, and contractor services and support.

Created and led a multidisciplinary data mining group from bioinformatics, biostatistics, and information sciences areas. Provided integrative analysis techniques that substantially impacted several project teams.Recruited scientists from diverse backgrounds and transformed them into a high performance data mining/data analysis team.Established the group as the global corporate experts in the analysis of genomics and genetics scale dataDelivered numerous biomarker and target discovery analyses in Oncology, Diabetes, and Obesity to Research staff.Line management responsibility for all technical staff and contractors. Budgetary oversight for personnel, projects, and external contractor services and support.

Introduced bioinformatics and biostatistics as a critical part of the Roche discovery process. Analyst for genomics and genetics data for the Oncology disease area. Championed three potential targets to the Oncology target discovery team.Managed Affymetrix Genechip project pipeline across all Nutley disease areasAnalyzed diverse data from microarrays, in vivo/vitro assays, genetic studies, and proteomics.Global site representative to corporate strategy team for global bioinformatics and genomics technologies.