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Proven leader bringing a wealth of expertise (engineering, manufacturing, and operations) to the table with a primary focus on driving the commercial success of cutting-edge chemical and biochemical products. Career is underscored by hands-on experience executing capital projects exceeding $750 million. Execution and oversight of the design, construction, start-up, and ongoing operation of two groundbreaking facilities in the US and Singapore. International experience encompassing fermentation facilities in Brazil, Europe, and the US, as well as spearheading major plant expansions, retrofits, and the design, construction, and operation of multiple pilot plants.My multifaceted journey through the domains of Manufacturing, Engineering, R&D, Project Management, Quality, Supply Chain, and Environmental Compliance attests to my broad-based skill set. My approach is rooted in a commitment to excellence and a passion for transformative initiatives that span diverse industries. From pioneering new products to optimizing processes for superior quality and cost efficiency, I've consistently delivered results that speak volumes.Most recently, I've directed my executive experience towards nurturing biotech startups, weaving together my engineering acumen and hands-on experience in manufacturing and operations. My success lies in building organizations from the ground up, orchestrating breakthroughs in R&D, engineering, and operations. My track record has achievements across biochemicals, chemicals, food, pharma, and beyond—a testament to my adaptability in navigating complex business landscapes.My international footprint is marked by a collaboration with manufacturing, research, and technology providers across Europe, North & South America, Singapore, and Australia. I've played pivotal roles in the commercialization of game-changing products, from Splenda Sucralose to Amyris' Renewable Fuels and Chemicals, Aurora Algae's Nutraceuticals, Evolva's health and F&F products, Genomatica's full line of products, and most recently, the revolutionary microbes at Pivot Bio.Core Skills: Operations Management | Manufacturing Strategy | Chemical Process Engineering | Bioprocessing (Fermentation and DSP) | Contract Manufacturing Management (CMO/CDMO) | Contract Negotiations | Process Improvement/Optimization | Operational Excellence (Lean, Six Sigma) | Plant Design | Project Management | R&D Management | cGMP/FDA
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Vice President Of ManufacturingCambium Jul 2024 - PresentEl Segundo, Los Angeles, Ca, Us
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Founder/Principal ConsultantScale Right Now Llc Dec 2023 - PresentProvide C-Suite Advisory and Engineering/Technical Services:Manufacturing Strategy (Contract vs Own-Operate), Fractional/Transitional leadership, Process Development and Scale-up Strategy, Technoecomic Analysis (CAPEX/OPEX), Investor Due Diligence, Facility Design and Process Risk Assessment/Oversight, Site Evaluation/Selection, Operational Excellence -
Vp Of Manufacturing And Supply ChainPivot Bio Oct 2021 - Nov 2023Berkeley, Ca, Us- Simultaneously oversaw Manufacturing, Supply Chain, and Quality. Formulated a comprehensive staffing plan for short, medium, and long-term objectives, initiating an extensive recruitment drive both internally and externally- Spearheaded the establishment and expansion of production for the groundbreaking PROVEN® 40 LIF (Liquid in Furrow) and PROVEN® 40 OS (On Seed) products in Crop Year 2022 (CY22), ensuring a seamless transition to the new flagship products. Initiated contract negotiations with existing CMOs and secured agreements with multiple additional CMOs to fulfill the heightened production demands.- Overcame formidable challenges to achieve an unprecedented 300% expansion in production capacity for Crop Year 2023, building upon the already remarkable >400% increase in the previous year. Required innovative/creative work with R&D and careful negotiations with Pivot Commercial.- Implemented a strategic vision by rapidly developing both internal and external capabilities, identifying and integrating a new and untested CMO in a matter of weeks. Orchestrated the construction and operationalization of a new drying and powder processing facility, a Quality lab, and warehouses in both St. Louis and Omaha within a tight six-month timeframe. -
Vp, Commercial OperationsGenomatica Apr 2019 - Sep 2021San Diego, Ca, Us- Drove process and plant efficiencies to deliver >200% more BrontideTM BG to the market with 20% lower costs and higher quality.- Built and managed contract manufacturing network to support commercial sales of all Geno products. Secured new manufacturing capability to complete first ever scale up and production of Geno’s second two commercial products.- Built out the operations team from scratch (Quality, Safety, Environmental, Regulatory, etc.).- Transformed production while enhancing the commercial viability of the flagship product, Brontide® butylene glycol for cosmetics. Navigated complexities to double production capacity while rectifying product quality concerns.- Addressed intricate product quality issue, which demanded innovation; devised a groundbreaking processing technology and identified a CMO for further processing, culminating in delivery of a higher-quality product. - Drove the successful simultaneous launch of two pivotal products for Geno—AvelaTM natural ® 1,3 Butanediol, a ketogenic food ingredient, and a groundbreaking fragrance ingredient from the portfolio of acquired REG Life Sciences business.- Orchestrated the development and scaling of a new process for AvelaTM within a narrow timeframe of less than 6 months. Authored all technical documents required for regulatory approval and facility qualification at selected CMO. Led design, procurement, and installation of all processing equipment at the CMO, ensuring a seamless production transition. - AvelaTM was successfully launched, meeting desired volumes, stringent quality standards, and cost targets. -
Svp Operations - Vp Manufacturing And EngineeringEvolva Group Aug 2014 - Apr 2019Reinach, Ch- Built strong, international Contract Manufacturing network (US/NA, EU; 11 facilities): established contracts, obtained certifications (API, Food Ingredients, F&F, Biopesticides, Kosher, Halal), completed technology transfers, and managed day-to-day activities.- Directed Quality, Safety, Manufacturing, Supply Chain, and Engineering functions while commercializing numerous global products: Veri-teTM resveratrol, NootkashieldTM nootkatone, eveValenceneTM, and eveNootkatoneTM.- Minimized costs via “just in time” and “capital light” spending. Established record of reducing manufacturing costs (75% reduction from launch COGs) by deploying new production strains (6) and continuously improving DSP processes. -
Vp, Engineering And Downstream Technology - Sr Dir Process CommercializationAurora Algae, Inc Sep 2012 - Jul 2014Hayward, Ca, Us- Completed contract negotiations, tech transfer to CMO’s, and first commercial production of A2 Omega 3 oils (EPA Pure and Multi-Omega). Developed new process technologies with higher yields (>10%) and less equipment (saving >$10M).- Provided visionary leadership in leading/directing Downstream Process R&D and Contract Manufacturing.- Developed new scale-up/manufacturing strategy which saved >$20M in CAPEX and shortened time to market by >1 year. -
Sr. Director, Manufacturing And EngineeringAmyris Inc Nov 2009 - Sep 2012Emeryville, Ca, Us- Supported Lubricants/Base Oil, Polymer, Plastic Additive, and F&F commercial teams. Improved recovery yields of BioFene™ by >20% and purification yields by >5%. Effectively managed Amyris’ first large scale BioFene™ project.- Led global effort to produce Amyris’ full line of No Compromise® Renewable Chemicals. CMO selection/management, cost modelling, tech transfer, plant design, capital project management, operations support, and process optimization.- Served as Operations Director for Specialty Chemical Contract Manufacturer, Glycotech, in North Carolina. Built operations team from 3 to 35, producing and delivering first on spec product in <4 weeks. Designed, built, and launched a novel multi-step distillation train in <5 months. -
Director Of Process TechnologyTate & Lyle Jun 2006 - Nov 2009London, England, GbLed an international development team, with members in the US, Europe, and Singapore, focused on improving the cost and operability of the the process to manufacture Splenda Sucralose. Developed technologies responsible for reducing costs by >$20 million per year, primarily through chemical yield increases and improved raw material utilizations. -
Project ManagerTate & Lyle Apr 2004 - May 2006London, England, GbLed project to double the capacity of the Splenda Sucralose facility in McIntosh, Alabama.
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Manager, Process Technology And Environmental AffairsJohnson & Johnson Sep 2002 - Apr 2004New Brunswick, Nj, UsManaged all process improvement efforts for Splenda Sucralose Manufacturing. Also managed all environmental compliance and permitting efforts and activities. -
Plant Services ManagerJohnson & Johnson Jan 1999 - Aug 2002New Brunswick, Nj, UsLed the Utility Operations, Purification Operations, Maintenance, Purchasing, and Environmental Compliance teams during the start-up phase of the Splenda Sucralose manufacturing facility in Alabama.
Jim Wiley Skills
Jim Wiley Education Details
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Georgia Institute Of TechnologyChemical Engineering -
CaltechIndustrial Relations Center
Frequently Asked Questions about Jim Wiley
What company does Jim Wiley work for?
Jim Wiley works for Cambium
What is Jim Wiley's role at the current company?
Jim Wiley's current role is Executive Leader & Consultant in Manufacturing, Engineering, and Operations.
What is Jim Wiley's email address?
Jim Wiley's email address is jw****@****ica.com
What is Jim Wiley's direct phone number?
Jim Wiley's direct phone number is +151050*****
What schools did Jim Wiley attend?
Jim Wiley attended Georgia Institute Of Technology, Caltech.
What skills is Jim Wiley known for?
Jim Wiley has skills like Process Engineering, R&d, Chemical Engineering, Process Simulation, Manufacturing, Project Management, Biotechnology, Manufacturing Operations, Gmp, Commercialization, Engineering, Start Ups.
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