Jin Yu Email & Phone Number

Los Angeles, Ca, Us

Los Angeles, Ca, Us

Thousand Oaks, Ca, Us

Lawrence Township, Nj, Us

• Designed an experiment to support part of the PPQ campaign by isolating/characterizing a DP impurity using SEC and HPLC.• Performed downstream mAb-based drugs IPC following GxP practices and supported PPQ, CPA, PAI campaign studies.• Tested eco-friendly detergent candidates for manufacturing process optimization and provided data for the patent filing.• Contributed to the multi-week development runs by packing/running AKTA columns, UF/DF, TFF and HPLC.• Supported MS&T downstream adopt TECAN by giving literature reviews of TECAN technology in manufacturing science and testing methods for column qualification, sample collection and testing.• Reviewed experiment data and calculations for FDA filing, interpreted data with JMP, and drafted AKTA new-user book.

Boston, Ma, Us

Project 1 Overview: Colloidal stability of core-shell superparamagnetic iron oxide nanoparticles (SPIONs) as an NMR contrasting agent.• Innovated a new polymer as SPIONs coating, and designed coating grafting/exchanging route.• Investigated core-shell SPIONs chemical integrity, size, surface charge, surface coating density, colloidal stability with various instruments (GPC, FTIR, TGA/DSC, TEM, DLS/zeta potential and UV-vis spectroscopy etc.).• Purified chemicals/materials with different chromatography columns, dialysis, centrifugation and filters, and analyzed the final substance with instruments such as GPC and NMR.• Scaled-up protocols in order to better acquire various materials property data.• Developed storage methods for new molecules and biomaterials (e.g. lyophilization).• Collaborated with theoretical chemists to study the fundamental properties that impact colloidal stability of nanoparticles in the desired environments.• Analyzed data with Python, GraphPad Prism, and Microsoft Excel for publishing and presentations.Project 2 Overview: Developed highly magnetizable lipid-nanoparticles with the ability to target natural IgM-producing phagocytic B cells (NIMPAB cells) in order to develop IgM cancer vaccine.• Designed lipid coated micelles using o/w emulsion and successfully increased encapsulation efficiency of magnetic cores (3mg/ml to 5mg/ml).• Analyzed micelle stability in different solvents and measured the concentration with nanoparticle tracking analysis (NTA).• Collaborated with immunologists and developed cell assays to examine material-cell interaction, and magnetic purification efficiency. • Analyzed cell assay results with FACS and time-lapse fluorescence microscopy.• Trained and supervised one undergrad and two graduate students to develop research projects (e.g. Comsol simulation of magnetic nanoparticles’ response to external magnet with different geometries; nanoparticle formulation and stability experiments).

Boston, Ma, Us

• Collaborated with 4 MBA students to design a novel packaging system as the only engineer on the team.• Conducted research with extensive reading on the food industry and agriculture within a month.• Drafted documents for case practices and team building activities.

Boston, Ma, Us

• Taught undergraduate courses: Physics Lab, Chemistry Lab, and Systems Physiology.• Developed final exams, and trained students on report writing.• Coordinated grading and labs with teams of teaching assistants.

Ann Arbor, Michigan, Us

• Synthesized thermoelectric metal composites to convert thermal energy to electric energy using mechanical milling.• Analyzed crystal structures to improve energy concerting efficiency with SEM, and XRD.• Synthesized microfibers and microparticles using high voltage jetting to create potential drug carriers.

Beijing, Cn

• Cultured stem cells and collect cell migration data daily with an established assay.

Doctor Of Philosophy (Ph.D.), Materials Science And Engineering

Bachelor Of Science In Engineering (B.S.E.), Material Science And Engineering

Chemical Engineering