Development of a system for computer-aided design.

LabWeb: easy-to-use web system for management of laboratory-related documents which helps to archive important internal documents or public materials (posters, presentations, etc.) published by nearly 50 members of Loschmidt Laboratories. It supports full-text search, autoconversion to PDF, various e-mail alerts, draft approval and many other customizations. LabWeb is based on WordPress platform.

EnzymeMiner: software that identifies putative members of enzyme families and facilitates the selection of promising targets for experiments. https://loschmidt.chemi.muni.cz/enzymeminer/Hon, J., Borko, S., Stourac, J., Prokop, Z., Zendulka, J., Bednar, D., Martinek, T., & Damborsky, J. (2020). EnzymeMiner: automated mining of soluble enzymes with diverse structures, catalytic properties and stabilities. Nucleic Acids Research, 48(W1), W104–W109. https://doi.org/10.1093/nar/gkaa372SoluProt: software for sequence-based prediction of soluble protein expression in Escherichia coli created using the gradient boosting machine technique with the TargetTrack database as a training set. https://loschmidt.chemi.muni.cz/soluprot/Hon, J., Marusiak, M., Martinek, T., Kunka, A., Zendulka, J., Bednar, D., & Damborsky, J. (2021). SoluProt: prediction of soluble protein expression in Escherichia coli. Bioinformatics, 37(1), 23–28. https://doi.org/10.1093/bioinformatics/btaa1102