Jake Kinsella
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Jake Kinsella Email & Phone Number

Scientist I at Insmed Incorporated
Location: Cambridge, England, United Kingdom 10 work roles 5 schools
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Current company
Role
Scientist I
Location
Cambridge, England, United Kingdom
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Who is Jake Kinsella? Overview

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Jake Kinsella is listed as Scientist I at Insmed Incorporated, a with 1472 employees, based in Cambridge, England, United Kingdom. AeroLeads shows a matched LinkedIn profile for Jake Kinsella.

Jake Kinsella previously worked as Target Validation Associate Scientist at Cerevance and MRes Medicine Student at University Of Leeds. Jake Kinsella holds Master Of Research (Mres), Medicine, Distinction from University Of Leeds.

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Insmed Incorporated

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About Jake Kinsella

Target Validation Associate Scientist at Cerevance with multidisciplinary Target Validation experience spanning both neurodegenerative drug discovery and cancer biology.Experience with: A range of cell models including primary mouse and hIPSC-derived cultures as well as patient-derived and established cell lines. 3D in vitro patient-derived spheroid and ex vivo ‘tumour-on-chip’ cancer models of intact patient tissue.Multiple expression manipulation technologies including rAAV transduction, lipofection, nucleofection, and passive-delivery siRNA transfection. Cell-based assay formats including live-cell imaging phagocytosis/ chemotaxis/ cytotoxicity, cytokine HTRF, cytokine 10 x MSD, cell viability and cytokine stimulation. DNA/RNA/Protein sample preparation and expression analysis including PCR, RT-qPCR, Western Blot, ICC and IHC.High-content, live cell and confocal microscopy. Human and mouse tissue handling, including primary cell culture preparation from mouse brain tissue and chemotherapy treatment of human tissue. Master of Research in Medicine with Distinction, University of Leeds. Project/Dissertation title: ‘Evaluating the use of ‘self delivering’ siRNA to modulate target gene expression in an ex vivo ‘tumour-on-chip’ model of glioblastoma.’Bachelor of Science in Biochemistry with First Class Honours, University of East Anglia (UEA). Project/Dissertation title: ‘Investigating the influence of neuropilin-1 and neuropilin-2 on angiogenic signalling in cancer.’

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Jake Kinsella's current company

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Insmed Incorporated
Insmed Incorporated
Scientist I
Cambridge, GB
Website
Employees
1472
AeroLeads page
10 roles

Jake Kinsella work experience

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Target Validation Associate Scientist

Cambridge, England, United Kingdom

Mres Medicine Student

Leeds, England, United Kingdom

During my MRes Medicine degree, I undertook a nine-month research project focusing on generating transient knockdown models of 3D in vitro and ex vivo ‘tumour-on-chip’ models of glioblastoma, using self-delivering siRNA. Within the project, I gained experience working with multiple patient derived glioblastoma cell lines in 2D and 3D spheroid cultures (96 well format), ex vivo ‘tumour-on-chip’ microfluidics models of intact patient tissue, siRNA transfections, chemoradiotherapy treatment of in vitro/ ex vivo models, RT-qPCR, cell-based cytotoxicity/viability assays and confocal microscopy.

Sep 2022 - Aug 2023

Student Ambassador For The School Of Biological Sciences And School Of Chemistry

Sep 2021 - Jun 2022

Bsc Biochemistry Student

Norwich, England, United Kingdom

My Bachelor’s degree project, undertaken in the Robinson Laboratory at the Quadram Institute (Norwich Research Park), sought to understand how two VEGFR-2 co-receptors, NRP1 and NRP2, influenced pathological angiogenesis in breast cancer.Primarily, the project involved IHC of breast cancer tumour tissue excised from WT or NRP1/NRP2 dual knockout mice. I was responsible for sectioning over 100 tissue sections, staining for various phosphorylated proteins associated with VEGFR-2 downstream signalling cascades, and imaging slides to assess the abundance of phosphorylated angiogenic proteins within WT and NRP1/NRP2 KO mice breast cancer tumour microvasculature. Additionally, the project also gave me exposure to in vitro endothelial cell culture, VEGF-a signalling assays and Western Blotting.

Sep 2018 - Jun 2022

Customer Service Assistant

Chelmsford, England, United Kingdom

Mar 2019 - Jan 2021

Warehouse Operative

Chelmsford, England, United Kingdom

Jan 2018 - Jan 2019
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Colleagues at Insmed Incorporated

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5 education records

Jake Kinsella education

A-Level, Physics

Chelmer Valley High School

A-Level, Chemistry

Chelmer Valley High School

A-Level, Biology

Chelmer Valley High School
FAQ

Frequently asked questions about Jake Kinsella

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What company does Jake Kinsella work for?

Jake Kinsella works for Insmed Incorporated.

What is Jake Kinsella's role at Insmed Incorporated?

Jake Kinsella is listed as Scientist I at Insmed Incorporated.

Where is Jake Kinsella based?

Jake Kinsella is based in Cambridge, England, United Kingdom while working with Insmed Incorporated.

What companies has Jake Kinsella worked for?

Jake Kinsella has worked for Insmed Incorporated, Cerevance, University Of Leeds, University Of East Anglia, and Hm Courts & Tribunals Service (Hmcts).

Who are Jake Kinsella's colleagues at Insmed Incorporated?

Jake Kinsella's colleagues at Insmed Incorporated include Benjamin Hardiman, Shayla Gamble, Adam Holderman, Nadia Capuano, and Diane Benevento.

How can I contact Jake Kinsella?

You can use AeroLeads to view verified contact signals for Jake Kinsella at Insmed Incorporated, including work email, phone, and LinkedIn data when available.

What schools did Jake Kinsella attend?

Jake Kinsella holds Master Of Research (Mres), Medicine, Distinction from University Of Leeds.

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