Jim Mcguire Email and Phone Number
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With extensive experience leading drug discovery workflows and advancing projects from ideation to IND in diverse therapy areas and molecular formats, I bring scientific leadership backed by a broad background in pharmacology, biochemistry, and chemistry. Pharmacology Expertise: Made significant contributions to 15 projects that advanced to lead candidate selection across multiple organizations.Metabolic Indications: Obesity, Diabetes, MASH/NASHRegulatory Success: Delivered critical pharmacology packages and formal feedback to authorities, supporting the approval of semaglutide (Ozempic) for diabetes treatment.Consulting: Fractional Head of Pharmacology roles with focus on getting assets to IND/CTA.Core Competencies:Drug Development | Pharmacology | PK/PD | Target Biology | Biologics | Multivalent Scaffolds | Assay Cascades | Indication Selection | Exploratory/New Projects | IPR Strategy | Building Pipelines | Academic Collaborations | CRO Management | Fiscal Responsibility
Biologics And More Consulting
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Chief Executive OfficerBiologics And More Consulting Oct 2022 - Present
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ConsultantCatalyst Biosciences Apr 2022 - Oct 2022South San Francisco, Ca, Us -
Executive DirectorCatalyst Biosciences Feb 2022 - Apr 2022South San Francisco, Ca, Us
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Senior DirectorCatalyst Biosciences Jun 2020 - Feb 2022South San Francisco, Ca, UsDriving drug discovery through design and characterization of novel proteases as biopharmaceuticals in rare diseases and systemic complement-mediated disorders...
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ConsultantNovo Nordisk Jan 2020 - Jun 2020Bagsværd, Dk -
Principal ScientistNovo Nordisk Nov 2014 - Mar 2019Bagsværd, DkFocus on the biology of peptide hormones and their application in diabetes and obesity. I led small to large teams delivering in vitro pharmacology data on a variety of molecular formats including multi-functional fusion proteins, multi-agonists and conjugates. Responsible for bioassay development for screening through IND. Heavily involved at the interface of chemistry and biology to improve PK/PD properties of lead structures. Routinely involved in maturation of early innovation projects.
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Team LeaderNovo Nordisk Jan 2014 - Nov 2014Bagsværd, DkManager for In Vitro Receptor Pharmacology team (20+ members) in diabetes and obesity. Developed bioassay systems to predict PK properties in man and PK/PD across preclinical species.
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Senior ScientistNovo Nordisk Jan 2009 - Jan 2014Bagsværd, DkWorked with peptide hormones in diabetes and obesity. Responsible for a variety of assay formats and intracellular signalling (e.g., high content imaging, GPCR readouts, insulin signalling, receptor binding, metabolomics). Automation expert involved in designing and optimizing workflows.
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Senior Research FellowNovo Nordisk Aug 2006 - Dec 2008Bagsværd, DkGroup leader for proteomics biomarker discovery in diabetic nephropathy and type 2 diabetes. Worked on establishing epidemiological proteomics workflow. Responsible for setting research agenda, securing funding and recruitment of students.
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ManagerCiphergen Biosystems Apr 2000 - Aug 2006UsManager of biomarker discovery CRO working with pharmaceutical industry. Established new proteomics workflows to work on individual patient or animal samples. Led internal efforts to establish peptide biomarkers for Alzheimer's disease. High degree of customer contact and stakeholder engagement coupled with highly technological workflows. -
Research ScientistLundbeck Jan 1999 - Apr 2000Valby, Copenhagen, DkFocus on LC and LC-MS workflows in ADME of small moleculesEstablished GLP in department -
Post DocKøbenhavns Universitet - University Of Copenhagen Mar 1996 - Dec 1998København K, DkWorked on expression and characterization of enzymes involved in nucleotide biosynthesis
Jim Mcguire Skills
Jim Mcguire Education Details
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University Of Illinois Urbana-ChampaignChemistry -
Harvey Mudd CollegeChemistry
Frequently Asked Questions about Jim Mcguire
What company does Jim Mcguire work for?
Jim Mcguire works for Biologics And More Consulting
What is Jim Mcguire's role at the current company?
Jim Mcguire's current role is Drug Development | Pharmacology | Obesity | Metabolic Indications | IND/CTA | Peptides | Biologics | Small Molecules | Consulting.
What is Jim Mcguire's email address?
Jim Mcguire's email address is jm****@****ahoo.dk
What schools did Jim Mcguire attend?
Jim Mcguire attended University Of Illinois Urbana-Champaign, Harvey Mudd College.
What skills is Jim Mcguire known for?
Jim Mcguire has skills like Protein Chemistry, Molecular Biology, Biochemistry, Mass Spectrometry, Lifesciences, Proteomics, Drug Discovery, Immunology, Cell Biology, Biotechnology, Cell Culture, Protein Purification.
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