João Ricardo Bueno De Morais Borba Email and Phone Number
Currently pursuing a postgraduate certificate in Project Management at Mohawk College. Graduated and post-graduated from UNIFAL-MG, in Brazil. M.Sc. in Physical Chemistry applied to Medicinal Chemistry with a focus on Bioinformatics, and a B.Sc. in Pharmaceutical Sciences, whose Canadian equivalency has been attested by WES. In 2013, while pursuing my bachelor’s degree, I was awarded a scholarship by the Brazilian government to study at the University of Toronto for one and a half years. During this time, I improved my English proficiency, took courses related to Pharmaceutical Sciences, and conducted research at CAMH (Centre for Addiction and Mental Health), Canada’s largest mental health teaching hospital and one of the world’s leading research centres in the field. With over 5 years of experience as an Analytical Development Analyst on the R&D team in Brazilian pharmaceutical companies, I have gained extensive experience in developing methodologies for dissolution studies, including innovative methods with USP 3/BIO-DIS and USP 4 apparatuses, as well as biphasic systems for in vitro/in vivo correlation (IVIVC). Additionally, I developed various chromatographic and spectrophotometric analytical methods, conducted the analytical validation of some of them, performed stability/shelf-life studies, forced degradation studies, and wet chemistry/analytical bench techniques. Data analysis and acquisition were carried out using Empower, EZChrom, and OpenLab software. I am well-versed in GLP, GMP, and SOPs, and familiar with both Brazilian and international regulations from ANVISA, FDA, Health Canada, and ICH guidelines.I am responsible, honest, and well-mannered. My strongest transferable skills include a strong work ethic, dependability, collaboration and teamwork, corporate etiquette, critical thinking, adaptability, attention to detail, proactivity, time management, and a commitment to problem-solving.
Silver Fox Pharmacy Inc.
View- Website:
- SilverFoxRx.ca
- Employees:
- 72
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Pharmacy AssistantSilver Fox Pharmacy Inc.Hamilton, On, Ca -
Mobile Ice Cream Parlour AssociateCrazy Cravings May 2024 - Sep 2024Greater Toronto Area, Canada• Efficiently processed customer orders and provided the best experience with hard ice cream• Always provided information to customers with a smile on my face• Managed payments by operating cash registers as well as credit card and debit machines• Tracked the number of cups sold at private events (record-keeping practices)• Harmonized teamwork with customer service efficiency• Re-stocked and organized products• Cleaned and neatened the shop, trailer and two vans before and after events or street sales
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R&D ChemistEurofarma Dec 2019 - Jul 2021Itapevi, São Paulo, Brazil• Developed innovative biphasic dissolution methods with the aim of correlating in-vitro results with in-vivo findings (IVIVC), both before bioequivalence studies and after unsuccessful ones, using 708-DS Agilent dissolution testers coupled with 850-DS sampling stations;• Developed dissolution methods to evaluate drugs, including those belonging to the class II of BCS and the subclass IIb of DCS, using Hanson Vision® G2 Classic 6™ and Elite 8™ dissolution testers coupled with AutoPlus™ sampling stations as well as Varian Vankel VK7000/7010 dissolution testers also coupled with sampling stations;• Developed a singular drug degradation products method using the HILIC technique;• Conducted post-dilution method development for IV drugs;• Transferred analytical methods that had been developed by third-party companies;• Performed official routine analyses comprising assay, impurities/degradation products and dissolution testing of new products scaled for the first time to be launched on the market. -
Junior R&D ChemistEurofarma May 2017 - Nov 2019Itapevi, São Paulo, Brazil• Developed dissolution methods not only for QC analyses, but also for biorelevant testing at the Analytical Development lab. These studies have included USP 3 (BIO-DIS) apparatus to assess both extended release and delayed release formulations, and USP 4 apparatus to evaluate immediate release formulations, so that IVIVC could be predicted ahead of bioequivalence studies;• Developed assay and physicochemical methods to appraise lyophilized antineoplastic and antimicrobial drugs;• Validated methods developed in loco. Performed tests included linearity, accuracy, stability, filter testing and selectivity, in accordance with the Brazilian legislation “RDC 166/17”, which is based on ICH guidelines;• Conducted forced degradation studies and wrote their official reports according to a Brazilian legislation called “RDC 53/15”, which is also based on ICH guidelines;• Validated an impurity profiling method developed using a QDa detector of an UPLC-MS equipment;• Conducted process validation studies;• Performed routine analyses of pilot batches;• Actively investigated out-of-specification issues;• VWD e DAD chromatography detectors and the Empower software were used on a daily basis, while the Light Scattering chromatography detector and the OpenLab software were used to analyze only phytochemicals; -
Junior R&D ScientistEms Jan 2017 - May 2017Hortolândia, São Paulo, Brazil• Performed stability studies of marketed products in accordance with a Brazilian legislation, named “RDC nº 45/2012”, which is based on ICH guidelines;• Conducted wet chemistry (mainly titration) and assay/impurities testing via UV-visible spectrophotometry and HPLC/UPLC techniques in association with the EZChrom and Empower programs on Agilent and Waters instruments, respectively;• Performed dissolution testing on Hanson SR8Plus dissolution testers, with none coupled sampling stations. -
Junior R&D ChemistAlthaia S.A. Industria Farmaceutica Apr 2016 - Oct 2016Atibaia, São Paulo, Brazil• Analyzed samples via HPLC-DAD and HPLC-UV techniques, using Merck-Hitachi and Agilent instruments, and by UV-visible spectrophotometry, using Agilent and Shimadzu instruments;• Acquired and examined data through OpenLab and EZChrom programs, and performed dissolution testing via Hanson SR8Plus dissolution apparatuses with none coupled sampling stations;• Documented and reported results according to SOPs;• Conducted wet chemistry, including pH, density, and viscosity measurements, for solutions and suspensions;• Tested Pharmacopeial Methods from USP and BP monographs to identify drugs and to calculate their assay and impurity levels, as well as to assess their dissolution profiles when applicable;• Performed assay and impurities testing of raw materials, as well as assay, impurities testing and dissolution testing for stability/shelf-life studies;• Established comparative dissolution profiles between pilot batches and reference medicinal products aiming to achieve Pharmaceutical Equivalence;• Participated in forced degradation studies, as well as in validating analytical methods. -
R&D InternAlthaia S.A. Industria Farmaceutica Nov 2015 - Apr 2016Atibaia, São Paulo, Brazil• Analyzed samples via HPLC-DAD and HPLC-UV techniques, using Merck-Hitachi and Agilent instruments, and by UV-visible spectrophotometry, using Agilent and Shimadzu instruments;• Acquired and examined data through OpenLab and EZChrom programs, and performed dissolution testing via Hanson SR8Plus dissolution testers with none coupled sampling stations;• Performed assay and impurities testing of raw materials, as well as assay, impurities testing, and dissolution testing for stability/shelf-life studies;• Conducted titration and HPLC-DAD assay testing of raw materials;• Established comparative dissolution profiles in Hanson SR8Plus dissolution testers between pilot batches and reference medicinal products aiming to achieve Pharmaceutical Equivalence. -
Quality Control InternUniversidade Federal De Alfenas - Unifal-Mg Aug 2015 - Oct 2015• Performed wet chemistry for water analyses;• Conducted assay, impurities testing, uniformity of content, as well as dissolution and microbiological testing of capsules and tablets from local Compounding Pharmacy stores. -
Research Assistant InternCamh Foundation May 2014 - Aug 2014Toronto, Ontario, Canada• Participated in a preclinical research project that has investigated the effect of olanzapine on weight gain and energy expenditure in rats. It has involved intracerebroventricular (ICV) cannulation to assess central effects on weight gain and energy expenditure of olanzapine peripherally injected through subcutaneous injections. Also, weight gain was analyzed by weighing both rats and their food, and energy expenditure was calculated by Respiratory Exchange Ratio (RER) that measures the balance between CO2 and O2 volumes from expired air.• Collaborated in a small, pilot, double-blind, randomized, placebo-controlled clinical trial assessing metformin use as a potential alternative to treat psychotic people, mainly patients diagnosed with schizophrenia and schizoaffective disorder, who have prediabetes or diabetes. The study would last 2 years and approximately 20 participants would be enrolled.• Courses taken:- Animal User Training Program;- Good Clinical Practices (GCP) Training;- Responsible Conduct of Research (RCR) Training;- Tri-Council Policy Statement (TCPS) Training - Ethical Conduct for Research Involving Humans;- Blood Borne Pathogen (BBP) Training. -
Scientific Initiation Scholarship On Innovation And Technological DevelopmentCnpq - Conselho Nacional De Desenvolvimento Científico E Tecnológico Aug 2012 - May 2013Alfenas, Minas Gerais, Brazil• Wrote the pre-research project paper and conducted the research entitled “Computational studies through molecular docking of anti-inflammatory drug prototypes against Prostaglandin-endoperoxide synthase I and II enzymes”;• Evaluated the structure-activity relationship of drug prototypes using programs from the Schrödinger’s suite.
João Ricardo Bueno De Morais Borba Education Details
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Project Management -
Pharmaceutical Sciences -
Pharmaceutical Sciences
Frequently Asked Questions about João Ricardo Bueno De Morais Borba
What company does João Ricardo Bueno De Morais Borba work for?
João Ricardo Bueno De Morais Borba works for Silver Fox Pharmacy Inc.
What is João Ricardo Bueno De Morais Borba's role at the current company?
João Ricardo Bueno De Morais Borba's current role is Pharmacy Assistant.
What schools did João Ricardo Bueno De Morais Borba attend?
João Ricardo Bueno De Morais Borba attended Mohawk College, University Of Toronto, Universidade Federal De Alfenas, Universidade Federal De Alfenas.
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