Joep De Ligt Email & Phone Number

Amsterdam, NH, NL

Amsterdam, North Holland, Netherlands

Providing strategic leadership focussed on data (clinical & DNA) to enable the best possible care for current and future cancer patients. Hartwig does this through molecular (DNA & RNA) testing, accredited analysis, reporting and sharing of data fur further research based on patient consent.As part of the leadership team I focus on the data aspects of the.

Porirua - Aotearoa New Zealand

Obtaining useful and actionable results from genomics data often requires many different pieces of software and data, the bioinformatics & genomics plays a crucial role in this. ESR is New Zealand's national reference centre and genomics is used for pathogens (surveillance and outbreak management) as well as human (research as well as service delivery). A.

Porirua, Aotearoa New Zealand

While performing large scale genomics research I also coordinate several institute and campus wide efforts to support and improve computational research within Utrecht.Research topics include: Genomic langscape of cancers, Pharmacogenetic profiles, Genetic stability of organoids, Transcriptome profiling of organoids from different tissuesCoordination &.

Utrecht Area, Netherlands

Continuation of the work with the NKI started at the Hubrecht on the causes and consequences of genetic variation with a focus on cancer initiation and drug response.

Utrecht Area, Netherlands

After completing my thesis I started as a postdoctoral researchers at the Hubrecht in the lab of Edwin Cuppen to research genomic stability and its role in cancers.

Nijmegen Area, Netherlands

Conducting research in the Genomic Disorders group on detecting and interpreting de novo mutations, using Massive Parallel (Next Generation) Sequencing technologies.

Houston, Texas Area

Initiated collaboration with the group of prof. dr. James R Lupski MD, to study the accuracy of Copy Number Variation detection in Exome sequencing data. This was combined with an collaboration between BCM and RadboudUMC for which I analysed 200 exomes during my stay.Key publications include: de Ligt et. al. Human Mutation 34(10):1439-48, Yamamato et. al..

Nijmegen Area, Netherlands

Worked on the modeling of protein flexibility in the ROTACAL project under the supervision of Dr. G. Schaftenaar.

Lectures introducing the fundamental concepts of bioinformatics and introductions to the different areas of research within bioinformatics for first year and second BSc students.Generated Lecture material and exams

Oss, Netherlands

Worked on a drug design project for G-coupled protein receptors under the supervision of Dr. J. Klomp.

Research Doctorate, Human/Medical Genetics

Activities and Societies: Part of the GoNL structural variation team.PhD student at the NCMLS graduate school. Research performed within.

Master Of Science (Msc), Molecular Life Sciences, Bene Meritum

Specialisation - Bioinformatics

Master Of Science (Msc) (Joint With Radboud University Nijmegen), Bioinformatics

Part of the subjects for my degree in Nijmegen were selected from the Wageningen Bioinformatics curriculum and followed there.

Bachelor Of Science (Bsc), Bioinformatics

Activities and Societies: Member of the student accreditation team. After graduation, external assesor.