Leading and motivating a team that develops, validates, implements and outsources Pharmacokinetic (PK), Pharmacodynamic (PD), Biomarker and Immunogenicity assays across the pipeline from lead selection to licensing and post marketing commitments. Working with multi-disciplinary teams to drive bioanalytical strategy and ensure safety, tolerance and efficacy of our assets. Delivery of data and documents for regulatory submissions and regulatory responses for IND/CTA, EOP2, BLA etc. Accountable for global CRO vendor scientific oversight and vendor management for regulated bioanalysis when activities are outsourced at CRO partners for all modalities and therapeutic areas leading a global team. Experienced in RFIs, RFPs, KPIs and governance. Test Facility/Test Site Management and Legal Operator of the GLP and GCP for labs certified facility in Cambridge that is regularly inspected by MHRA. Previous experience as a Principal Investigator for multi-site GLP studies, Study Director for Method Validations and Analytical Project Manager for Clinical studies. European Federation of Pharmaceutical Industries and Associations (EFPIA) topic lead as the EWG member for ICH M10 Bioanalytical Method Validation (BMV) harmonisation which resulted in a single regulatory BMV guidance document for all ICH regions. Steering committee member of European Bioanalysis Forum (EBF) and previous committee member and previous co-chair of Drug Metabolism Discussion Group (DMDG). Current DMDG tutor, and company representative for European Immunogenicity Platform (EIP) and assay sub-team member. AAPS ADA Harmonisation team member and subteam lead for ADA Selectivity resulting in a key industry White Paper. Member of the Granta Park site leadership team, Granta Park Safety, Health and Environment committee chair and a member of the AZ Human Biological Samples Governance Council. Actively mentoring and coaching 2 individuals in different areas of the business plus my global team.

Leading the global team responsible for the scientific management of bioanalytical outsourcing for all drug modalities and therapeutic areas of the AstraZeneca pipeline, and the GLP and GCP certified lab in the UK responsible for in-house regulated bioanalysis.

Interim Head of Bioanalytical Sciences within Clincal Pharmacology and DMPK

Responsible for a small team in the Bioanalytical Sciences Group within Translational Sciences, developing and validating Immunogenicity, PK and PD assays and performing subsequent sample testing for pre-clinical and clinical samples to GLP and GCLP regulations.Member of the British Association of Research Quality Assurance (BARQA)

Clinical Immunology and Biomarker Discovery Departments, Biopharm R&DDevelopment and valuation of immunoassays to support clinical trialsAnalysis of clinical samples

Evaluation of anti-dyslipidaemic and anti-atherosclerotic therapies

Cardiovascular Department

Molecular Sciences DepartmentEvaluation of anti-dyslipidaemic therapies in cardiovascular models

Industrial Placement Student in Chemotherapy Department investigating anti-microbial therapies.