Adjunct Associate Professor
South College
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John Bruno Email & Phone Number
Adjunct Associate Professor
at
South College
1 work email found
@nanohmics.com
2 phones found area 800 and 210
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Role
Adjunct Associate Professor
Location
Austin, Texas, United States
Who is John Bruno? Overview
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John Bruno is listed as Adjunct Associate Professor at South College, based in Austin, Texas, United States. AeroLeads shows a work email signal at nanohmics.com, phone signal with area code 800, 210, and a matched LinkedIn profile for John Bruno.
John Bruno previously worked as Principal Scientist and Director of Biotechnology at Nanohmics and Principal Scientist & Director of Biotechnology at Nanohmics. John Bruno holds Ph.D, Microbiology; Immunology from University Of Arizona.
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{first_initial}{last}@nanohmics.com
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Profile bio
About John Bruno
Career Summary/Highlights:- Spearheaded acquisition/licensing of DNA Aptamer technology to ApolloDx and CibusDx.- Led team at Pronucleotein, Inc. which won 2nd Place (49 competitors) in the 2014 FDA Food Safety Testing Tech Challenge ($120K in total prize money;http://www.foodsafetychallenge.com/).- Launched a profitable DNA Aptamer sales website www.OTCBiotech.com.- Winner of the 2011 Small Business Administration’s Tibbetts Award for Excellence in SBIR R&D.- Awarded > 80 SBIR/STTR, other federal and state R & D contracts totaling > $22.5M. - Published 117 total peer-reviewed journal articles, 8 book chaps. & inventor on 16 issued US & EU patents. - Edited & contributed 3 chapters to a book entitled "Biomedical Applications of Aptamers," Nova Science Publishers (formerly Plenum Press).- Patented a method for producing intrachain FRET-aptamers and assays - Patented and published a facile 3’ attachment chemistry to couple PCR products to proteins for low-cost industrial-scale mass production of DNA-3’-protein conjugates which are stable in vivo.- Invented and published DNA Aptamer-Complement conjugates to kill antibiotic-resistant infections (3 Patents Issued on Technology).- Invented and published DNA Aptamer-Fc opsonins to combat encapsulated pathogenic bacteria.- Developed & published DNA aptamer-based colloidal gold and fluorescent (nanoparticle and quantum dot-based) lateral flow test strips for the US Army to detect key hemorrhagic and other pathogenic viruses (e.g., Chikungunya, Crimean-Congo, Dengue, and West Nile viruses).- Developed an aptamer beacon assay for C-telopeptide (CTx) to monitor astronaut bone loss for NASA. Also developed N-acetylglucosamine and chitin aptamers to monitor recycled water aboard spacecraft for NASA under Phase 1 and Phase 2 SBIR contracts.- Invented and published novel FRET-Aptamer methodology and assays for bone markers, calcidiol, and organophosphorus nerve agent detection and quantification.
Listed skills include Biotechnology, Biochemistry, Molecular Biology, Microbiology, and 26 others.
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John Bruno's current company
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13 roles
John Bruno work experience
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Principal Scientist And Director Of Biotechnology
Principal Scientist & Director Of Biotechnology
Chief Science Officer
In charge of writing government BAA, SBIR, and STTR proposals and conducting cutting edge R & D for DNA Aptamer-based therapeutic, diagnostic, and biosensor technologies with the goal of spinning out a biotechnology company for OpTech currently called; Accrued ~ $11 M in government contracts by writing SBIR, STTR and BAA proposals. Provided patented aptamer intellectual property for ApolloDx/CibusDx in Utah. Highlights included publication of and patents for: 1) a novel 3' adenine attachment chemistry to enable mass production of NSF/NIH-funded long-lived therapeutic DNA-3'-protein conjugates, 2) novel DNA aptamer-C1qrs complement conjugates to kill antibiotic-resistant bacteria, cancer cells, and parasites, 3) aptamer-Fc opsonins, 4) ultrasensitive one-step adherent aptamer-magnetic bead-quantum dot assay for foodborne pathogen detection, and 5) DNA aptamer or FRET (Fluorescence Resonance Energy Transfer) aptamer development by novel patented methods to detect acetylcholine, nerve agents or their metabolites, and waterborne pathogenic bacteria. Authored 100 peer-reviewed research journal articles, 16 issued patents and one book about aptamer applications.
Jan 2003 - Aug 2018
Adjunct Professor
Taught evening courses including Introduction to Biotechnology (BITC 1311), Lab Methods & Techniques (BITC 1402) and Sophomore-level courses in Biotechnology Lab Instrumentation (BITC 2311), Cell Culture (BITC 2431), and Molecular Biology/Molecular Lab Techniques (2441), a hybrid Bio-Nanotechnology Lab Techniques course (BITC 2412 and NANO 2407) as well as Human Anatomy and Physiology and General Microbiology for Science Majors (BIOL 2420/2421). Received Two Adjunct Faculty Excellence in Teaching Awards for Biotechnology in 2009 and Microbiology in 2018. Also served as the Nanotechnology Program Advisory Committee Chairman 2015-2016. See ratings: http://www.ratemyprofessors.com/ShowRatings.jsp?tid=1274615.
Aug 2006 - May 2018
Vice President Of Biosensors & Biochemical Systems
Systems and Processes Engineering Corp. (SPEC) and OmniSite BioDiagnostics (Wholly Owned Subsidiary of SPEC), Sensors and Biosensors Division; Responsibilities included R & D of novel biomedical products, especially biosensors and associated biochemical reagents. In particular, responsible for implementing an in-house DNA Aptamer (SELEX: Systematic Evolution of Ligands by EXponential enrichment) program. Preparation of SBIR grants and proposals to various government agencies and all aspects of managing and executing contract R & D work. Accrued greater than $4M in government contracts as the proposal writer.
Jul 1999 - Jan 2003
Assistant Professor
UTHSCSA). Responsible for microwave bio-effects research on eukaryotic cell lines, development of nitrated protein assays and biological warfare detection technologies, including Systematic Evolution of Ligands by EXponential enrichment (SELEX, DNA Aptamer) development, at the Brooks Air Force Base (AFB) operating location. Self-funded position with a $200K Army R & D contract for anthrax aptamer development.
Jan 1997 - Jan 1999
Research Microbiologist
Involved in basic R & D of novel molecular recognition elements for use in biosensors for hazardous environmental wastes of concern to the Defense Dept. Projects involved screening of large random DNA libraries for high affinity binding Aptamers to small organic pollutant molecules by SELEX and exploration of electrochemiluminescent (ECL) properties of marine invertebrate metal ion accumulators (tunicates) and their blood pigments ("tunichromes") for detection and identification of toxic metal ions using biosensors.
Jan 1995 - Jan 1997
Adjunct Faculty Instructor
Taught at least 4 evening credit hours per semester in Microbiology, Human Anatomy & Physiology, or General Zoology.
Jan 1992 - Jan 1997
Research Microbiologist (Gs-13)
U.S. Air Force, Armstrong Laboratory, Crew Systems Directorate (AL/CFD) Detachment – Edgewood Research Development and Engineering Center (ERDEC), Aberdeen Proving Ground, MD. Involved in development of Immunomagnetic separation and detection devices (especially the IGEN (BioVeris) ORIGEN® ECL analyzer) and other biotechnologies (including PCR-based microbial identification) of concern to the Air Force and Army Chemical and Biological Defense Program. Aided IGEN/Bioveris to enter both the Biowarfare/Bioterrorism and Food Safety Testing markets via joint assay development, testing and publication. See papers in Biosensors & Bioelectronics & Appl. Environ. Microbiol. 1995-96. Developed a large volume immunomagnetic separator for blood via a $425K grant from USAMRIID, Ft. Detrick, MD from 1993-95. Obtained USAF patent for device and published work.
Jan 1993 - Jan 1995
Postdoctoral Associate
Involved in investigations of non-thermal microwave radiation effects on mammalian and bacterial cells. Work also focused on development of an intracellular chemiluminescent microwave- sensitive polymer (diazoluminomelanin; DALM) and nitrate reductase gene transfected macrophage nitrate metabolism. Work also resulted in the deposition of 3 new transfected cell lines (NR101, NR102 and NR8005) at American Type Culture Collection (ATCC
Jan 1991 - Jan 1993
Graduate Student/Research Assistant
Under Dr. George Olson centered on image analysis of retinoic acid-induced differentiation of HL-60 myeloid leukemia cells. Work also included cell culture, SDS PAGE, Western blotting, HPLC, immunoperoxidase and immunofluorescent staining of cytocentrifuged cell preparations, production of polyclonal rabbit antisera to bromodeoxyuridine, and ELISA. Taught an undergraduate Microbiology laboratory course and substitute taught Immunology lectures for my advisor.
Jan 1986 - Jan 1991
Cardio-Thoracic Research Assistant
Under Dr. Jack Copeland. Involved in investigation of heart transplantation rejection process, assisted in development of experimental immunosuppressive drug regimens for prednisone, cyclosporine, and anti-thymocyte globulin as well as an atrial natriuretic hormone (ANH) and urinary polyamine assays for detection of early transplant rejection responses and the pathologic progression of induced myocardial infarctions in canines.
Jan 1985 - Jan 1986
2 education records
John Bruno education
Ph.D, Microbiology; Immunology
University Of Arizona
B.S, Microbiology With A Chemistry Minor
University Of Arizona
FAQ
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What company does John Bruno work for?
John Bruno works for South College.
What is John Bruno's role at South College?
John Bruno is listed as Adjunct Associate Professor at South College.
What is John Bruno's email address?
AeroLeads has found 1 work email signal at @nanohmics.com for John Bruno at South College.
What is John Bruno's phone number?
AeroLeads has found 2 phone signal(s) with area code 800, 210 for John Bruno at South College.
Where is John Bruno based?
John Bruno is based in Austin, Texas, United States while working with South College.
What companies has John Bruno worked for?
John Bruno has worked for South College, Nanohmics, Operational Technologies Corporation (Optech), Northwest Vista College, and Spec (Systems & Processes Engineering Corp).
How can I contact John Bruno?
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What schools did John Bruno attend?
John Bruno holds Ph.D, Microbiology; Immunology from University Of Arizona.
What skills is John Bruno known for?
John Bruno is listed with skills including Biotechnology, Biochemistry, Molecular Biology, Microbiology, R&D, Protein Chemistry, Commercialization, and Immunology.
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