John Christopher Nolan Email & Phone Number

Galway, County Galway, Ireland

Galway, County Galway, Ireland

My research focused on the study and genetic characterisation of bone marrow-derived mesenchymal stem cells and their secreted factors, incorporating biomechanical and tissue-engineering strategies to advance the clinical application of MSCs for bone regeneration. In addition to investigating the potential of MSC cell therapy in bone regeneration, my.

County Dublin, Ireland

Neuroblastoma is a highly malignant paediatric cancer which varies greatly in its clinical behaviour and response to therapy, ranging from spontaneous regression to aggressive disease progression and death despite multimodal chemotherapy. This paediatric cancer, although very rare in its incidence (1/100,000) is responsible for ~15% of childhood cancer.

County Dublin, Ireland

This project demonstrated the significant increase in resistance to chemotherapeutic drugs with various mechanisms of action following the establishment of resistance to the frontline chemotherapeutic cisplatin, used in the treatment of neuroblastoma. We have identified key cytoskeletal genes, associated with resistance development and involved in invasive.

This position was awarded to me, as I acquired a top grade within my class of 45 students. I achieved a grade of 92% based on continuous assessment of my lab skills and problem solving ability throughout my Junior Sophister year.The research project I worked on, under the guidance of Dr. Anne Molloy, was based on the Biological and Clinical implications of.

Doctor Of Philosophy (Phd), Cancer Genetics

Investigation of the role of miRNAs in acquired chemotherapy resistance in Neuroblastoma.

Honours Bachelor Degree, Biochemistry And Cellular Biology, 2.1

Final year thesis project, " A role for Primary Amine Oxidase in p38 mediated Oral Inflammation."