John P Doherty Email & Phone Number

West Lafayette, Indiana, United States

Head of Method Development and Validation - Create, maintain, evaluate, and improve standardized tools for bioanalytical method development and validation activities. Ensure methods are developed and validated according to current bioanalytical guidelines with efficiency. Provide scientific and technical guidance to Principal Investigators to ensure appropriate development of bioanalytical methods. Act as the sponsor technical contact for all initial method development and validation project scope definition discussions. Liaise with sites regarding analytical method development activities.

Germantown, Md

Conduct research dealing with the understanding of human diseases and the improvement of human health. Engage in clinical investigation, research and development, or other related activities. Train personnel in the operation, maintenance, and troubleshooting of laboratory equipment. Prepare/review data tables and reports within Laboratory Information Management System (LIMS) - Watson™. Perform data transfers and clinical data management tasks. Conduct scientific investigations and efforts to troubleshoot/solve assay problems and process improvements. Comply at all times with the Laboratory Safety Policy and with company Standard Operating Procedures. Attend and present at Scientific Conferences. Develop and validate LC-MSMS assays to detect small molecule analytes independently.

South San Francisco, Ca

Execute qualitative and quantitative PK/ADME bioanalytical and analytical assays in biological matrices and dose solution using HPLC and LC-MS instrumentation. Manage databases, outsourced projects, and review data for quality.

Kennilworth, Nj

Supported the discovery, development and optimization of Biologics and Vaccine products by performing and troubleshooting existing techniques, and implementing new technologies.

East Hanover, Nj

Managed projects in development with timely support of investigational studies of active pharmaceutical ingredients in the drug pipeline enabling strategic decisions. Performing LC/MS/MS Quantitative analysis in a regulated laboratory to support pre-clinical toxicology and clinical activities, as well as, interpretation of pharmacokinetic (PK) data and statistical analysis. Also, manager of analytical outsourcing in multiple disease areas and Laboratory Management System Administrator for companywide instrumental accounting and part of the team initiating the integration of the calibration and maintenance records with multiple systems including the Electronic Laboratory Notebook (ELN).

Pearl River, Ny

Biopharmaceutical Chemist, Drug Metabolism and Pharmacokinetics (2005-2006)Study Director conducting permeability in rat intestinal in situ perfusion model and principle investigator of the bioanalysis requiring radionuclide handling. Responsible for study design, HPLC Quantitation method development, vehicle formulation, interdepartmental communications, instrument administration, writing protocols and reports, and determination of the BCS Class for all compounds in development.Bioanalytical Chemist, Drug Metabolism and Pharmacokinetics (2001-2005)LC/MS/MS Quantitative Method Development, Validation, and GLP sample processing by direct injection, liquid-liquid extraction, protein precipitation and Solid Phase Extraction using Multiprobe and Tomtec automated liquid handling systems. GLP notebook and logbook documentation. Write and review reports, SOPs and LOGs. Responsible for data analysis (chromatography, Pharmacokinetics, spectral interpretation etc.), experimental designs, data entry in Watson-LIMS, creating audit trails and the monitoring of several laboratories for safety compliance.

Edgewater, Nj

Rheology, Drop Point Analysis, Microscopy, and batch preparations.

Morristown, Nj

GMP Quality control responsibility for a new formulation of “Soft Soap” using a industrially advanced compounding process; quality assurance of raw materials, manufacturing phases, and finished batches for pH, viscosity, specific gravity, rheology, spectroscopy (UV-Vis), % solid, % moisture, refractive index, turbidity, titre, and GC and HPLC chromatography. Catalog, review, and enter data pertaining to OTC drug testing, batch adjustments and approvals.

Mount Olive, Nj

Inspect raw materials and finished goods for proper color, specific gravity, refractive index, and odor; determine purity by means of wet chemistry, infrared spectroscopy, and gas chromatography; catalog, review, and enter data.

Master’S Degree, Pharmacology

Bachelor’S Degree, Biology