The mission of Conifer Point is to be the premier provider of web-based, drug design tools so that researchers can access rigorous molecular modeling in user friendly format. To do this, the team at Conifer Point has made several key scientific breakthroughs in recent years in the field of fragment-based drug design that promise to have a transformative impact on the discovery of drugs. To make these innovations broadly available, we have developed a prototype Cloud-hosted Web application for chemical modeling and drug discovery including fragment-based design software that is unavailable in any other commercial software package. Other industry standard methodologies (energy minimization, docking) are also included. A computational platform arising from our efforts will be a first-in-class molecular design application that is delivered via a browser with fragment searches being run in the Cloud (Amazon Web Services). Please see https://www.boltzmannmaps.com for product information and for a free account!

http://blumberginstitute.org/My lab at the Blumberg specializes in four stages of preclinical drug discovery: high throughput screening, hit finding, hit-to-lead optimization, and lead identification. Some of the capabilities in my lab include:• Beckman Coulter’s Biomek FXP Laboratory Automation Workstation o Liquid handler for 96- and 384-well plate capability• Beckman Coulter’s Biomek 4000 Laboratory Automation Workstation o Liquid handler for 96-well capability• Microplate reader, automated, with stacker• 110,000 compound screening library with diverse biological and chemical space• 100,000 natural product extract library• Advanced informatics tools for vast data processing• In-house computer cluster and cloud accounts for quick, secure computational simulations• Biophysical screening and label-free detection with 384-well capabilities o Corning Epic o ThermoFluor• Computational chemistry software to assistant in the drug discovery process

As the Regional Assistant Dean of the Doylestown campus, I am in charge of all curricular and administrative functions of the campus. I also helped envision and start the new campus in Doylestown. Teaching responsibilities included Pharmacology, Professional Development, Seminars in Biomedical Sciences, and Biochemistry