John Newcomb

John Newcomb Email and Phone Number

Head of Drug Discovery @ Dynamic Cell Therapies, Inc.
Cambridge, MA, US
John Newcomb's Location
Cambridge, Massachusetts, United States, United States
John Newcomb's Contact Details
About John Newcomb

Experienced molecular cell biologist, group and project leader conducting preclinical small- and large-molecule drug discovery in the fields of oncology and inflammation. A proven record at implementing research strategy and managing multi-disciplinary scientific programs. Experienced in establishing and conducting research partnerships with biopharmaceutical, CRO and University collaborators. Recognized for strong scientific and technical ability, leadership and communication skills. Areas of research expertise include:Oncology: Receptor tyrosine kinase-mediated signal transduction; Wnt-pathway activation and differentiation in cancer cells; Tumor metabolism and energy regulation; Chromatin modifiers and epigenetics.Immunology: Immune receptor-mediated signal transduction; T-cell, B-cell and mast cell activation; Cytokine production and response; Antigen processing and presentation.Specialties: Molecular Cell BiologyOncologySignal transductionDrug DiscoveryInflammation

John Newcomb's Current Company Details
Dynamic Cell Therapies, Inc.

Dynamic Cell Therapies, Inc.

View
Head of Drug Discovery
Cambridge, MA, US
John Newcomb Work Experience Details
  • Dynamic Cell Therapies, Inc.
    Head Of Drug Discovery
    Dynamic Cell Therapies, Inc.
    Cambridge, Ma, Us
  • Dynamic Cell Therapies, Inc.
    Head Of Drug Discovery
    Dynamic Cell Therapies, Inc. Feb 2022 - Present
    Watertown, Ma, Us
  • Dynamic Cell Therapies, Inc.
    Head Of Drug Discovery
    Dynamic Cell Therapies, Inc. Mar 2021 - Present
    Watertown, Ma, Us
  • Takeda Pharmaceuticals
    Director, Head Of Molecular And Cellular Oncology
    Takeda Pharmaceuticals Jul 2013 - Mar 2021
    Tokyo, Jp
  • Millennium Pharmaceuticals
    Director, Head Of Molecular And Cellular Oncology
    Millennium Pharmaceuticals Jul 2012 - Mar 2021
    Cambridge, Ma, Us
  • Amgen
    Director, Research
    Amgen 2006 - Dec 2011
    Thousand Oaks, Ca, Us
    Hematology/Oncology Therapeutic Area – Responsible for a group of scientists involved in multiple small and large molecule pre-clinical drug discovery projects.• Experienced in project stages from target validation through lead candidate optimization and characterization, including development of pharmacodynamic biomarker assays.• Discovered and advanced novel inhibitors for 5 different targets• Researched, proposed and implemented a multi-target discovery platform in a novel area for the company• Serve on technical review committee to guide portfolio for global discovery research in oncology• Responsible for performance review and career development of staff• Provide leadership and mentoring for the group, including 5 Ph.D. level scientists and project leaders• Evaluate scientific direction and project target selection for the group
  • Amgen
    Associate Director, Research
    Amgen 2004 - 2006
    Thousand Oaks, Ca, Us
    Established the foundation for the Hematology/Oncology therapeutic area group at Amgen, Cambridge, MA. Recruited scientists and served as the main point of contact with senior leadership
  • Amgen
    Research Scientist Iv
    Amgen 2002 - 2004
    Thousand Oaks, Ca, Us
    Cellular Screening Group Leader and project leader for multiple small molecule drug discovery projects in inflammation and cancer therapeutic areas
  • Amgen
    Research Scientist Iii
    Amgen 2000 - 2002
    Thousand Oaks, Ca, Us
    Led interdisciplinary drug discovery project teams targeting EGF-R and IGF-1R receptor tyrosine kinases for oncology indications. Novel and potent small molecule inhibitors were identified.
  • Kinetix Pharmaceuticals
    Sr. Scientist
    Kinetix Pharmaceuticals Mar 1998 - Dec 2000
    Responsible for building cell biology and cell-based compound screening capabilities at a start-up small molecule biopharmaceutical company focused on discovery and development of novel kinase inhibitors. Managed relationships with CRO’s to obtain PK and in vivo efficacy data. Company was successful at building value in several cancer and inflammation projects and was purchased by Amgen in 2000.
  • Procept, Inc.
    Principal Investigator
    Procept, Inc. 1994 - 1998
    Project leader for small molecule immunosuppressive program. Managed scientific collaboration with Novartis.
  • Yale University School Of Medicine
    Howard Hughes Fellow
    Yale University School Of Medicine Feb 1991 - Feb 1994
    New Haven, Ct, Us
    Studied the role of Invariant chain in antigen processing and presentation by MHC class II molecules.

John Newcomb Skills

Drug Discovery Oncology Inflammation Group Leader Project Leader Pre Clinical Drug Discovery Molecular Cell Biology Cell Based Assay Development Pharmacodynamic Biomarker Assay Development

John Newcomb Education Details

  • Temple University - Lewis Katz School Of Medicine
    Temple University - Lewis Katz School Of Medicine
    Microbiology And Immunology
  • University Of Delaware
    University Of Delaware
    Biology

Frequently Asked Questions about John Newcomb

What company does John Newcomb work for?

John Newcomb works for Dynamic Cell Therapies, Inc.

What is John Newcomb's role at the current company?

John Newcomb's current role is Head of Drug Discovery.

What is John Newcomb's email address?

John Newcomb's email address is jo****@****eda.com

What is John Newcomb's direct phone number?

John Newcomb's direct phone number is +161744*****

What schools did John Newcomb attend?

John Newcomb attended Temple University - Lewis Katz School Of Medicine, University Of Delaware.

What skills is John Newcomb known for?

John Newcomb has skills like Drug Discovery, Oncology, Inflammation, Group Leader, Project Leader, Pre Clinical Drug Discovery, Molecular Cell Biology, Cell Based Assay Development, Pharmacodynamic Biomarker Assay Development.

Free Chrome Extension

Find emails, phones & company data instantly

Find verified emails from LinkedIn profiles
Get direct phone numbers & mobile contacts
Access company data & employee information
Works directly on LinkedIn - no copy/paste needed
Get Chrome Extension - Free

Aero Online

Your AI prospecting assistant

Download 750 million emails and 100 million phone numbers

Access emails and phone numbers of over 750 million business users. Instantly download verified profiles using 20+ filters, including location, job title, company, function, and industry.