John Butera

John Butera Email and Phone Number

Chief Scientific Officer and Senior Vice President of Research @ Hager Biosciences, LLC
New Jersey, United States
John Butera's Location
New Jersey, United States, United States
About John Butera

Provide vision, strategy, and focus to drug discovery efforts in biotech environment. A scientific leader with over 25 years of diversified experience as a leading drug hunter in the pharmaceutical industry. An expert medicinal chemist with a strong history of implementing award-winning leadership strategies to successfully manage Neuroscience and Cardiovascular / Metabolic Diseases chemistry portfolios. Extensive cross-functional experience in all phases of preclinical drug discovery including (i) early hit characterization (hit to lead), (ii) structure-activity and structure-property optimization, and (iii) development-track pre-clinical leads. Comprehensive background across numerous therapeutic areas including Neuroscience, Cardiovascular & Metabolic Diseases, Muscular-skeletal Disorders, Women's Health / Fertility, and Inflammation. Demonstrated talents in organizational management, communication, vision and direction, negotiation, and change leadership. Exceptional history of strong mentorship, coaching, developing effective interdisciplinary teams, increasing efficiency and productivity, and implementing creative strategies. A past key member of the Wyeth Chemical Sciences Leadership Team, provided significant overall contributions to the Wyeth R&D Discovery Objectives. More recently, co-founded Hager Biosciences, LLC, a privately-owned biopharmaceutical company, where he applies that experience to provide scientific vision and focus to discover new medicines.Specialties: Drug Discovery and Development BiotechnologyMedicinal ChemistryLead Validation (Hit to Lead)Lead Optimization (Structure-Activity Relationship & Structure-Property Relationship)ADME/PK OptimizationOrganic SynthesisParallel SynthesisNeuroscience & Cardiovascular Pharmacology Portfolio Management

John Butera's Current Company Details
Hager Biosciences, LLC

Hager Biosciences, Llc

View
Chief Scientific Officer and Senior Vice President of Research
New Jersey, United States
Website:
hagerbio.com
Employees:
8
John Butera Work Experience Details
  • Hager Biosciences, Llc
    Chief Scientific Officer And Senior Vice President Of Research
    Hager Biosciences, Llc
    New Jersey, United States
  • Hager Biosciences, Llc
    Chief Scientific Officer & Senior Vice President Of Research
    Hager Biosciences, Llc Aug 2010 - Present
    Privately-held / BiotechIn 2010, joined Hager Biosciences, LLC as a partner, Chief Scientific Officer, and Senior Vice President of Research. Implement and execute strategies to expand and develop the Hager Biosciences Business Model to deliver high-valued return on investment for our research partners, clients and investors.Implement operationally agile & effective drug discovery chemistry platforms such as FragPhoreTM for the pharmaceutical and biotech industries to provide licensable pre-clinical therapeutic leads and candidates and innovative medicinal chemistry solutions.
  • Pfizer
    Director, Neuroscience Medicinal Chemistry
    Pfizer Oct 2009 - Mar 2010
    New York, New York, Us
    Directed and managed a key portion of the chemical equity portfolio in Neuroscience and other therapeutic areas to ensure timely completion of research projects. Demonstrated expertise in the following target areas:Neurodegenerative Disease, Depression / Anxiety, Alzheimer's Disease, Neuropathic Pain, Inflammatory Pain
  • Pfizer
    Director Of Exploratory Medicinal Chemistry
    Pfizer Dec 2004 - Oct 2009
    New York, New York, Us
    Responsible for early med chem portfolio by heading Hit to Lead efforts in Neuroscience, Cardiovascular/Metabolic Diseases, Women's Health, and Tissue Repair at the Wyeth Princeton and Collegeville sites. Supervised and directed the research efforts of up to 21 chemists at 3 Wyeth research sites. The goal is to identify and characterize hits after an HTS. Use parallel synthesis to optimize SAR and SPR and identify viable chemotypes to push into lead optimization. Also responsible for several late stage Neuroscience Programs and Cardiovascular Programs. Led major collaborations with outside alliance partners.In addition to the Neuroscience target areas listed above, demonstrated expertise in the following target areas:Diabetes, Cardiac Arrhythmias, Urge Urinary Incontinence, Hyperlipidemia, Female Fertlity, Male Fertility, Fibroids, Fibrinolytic Impairment, Muscle Frailty, Allopecia, Osteoporosis, Vaso-motor Symptoms
  • Pfizer
    Associate Director
    Pfizer Jan 2000 - Dec 2004
    New York, New York, Us
    Provided line management oversight for numerous drug development programs in Neuroscience, Women's Health, Cardiovascular and Metabolic Disorders, and Muscular-Skeletal Disorders.
  • Pfizer
    Group Leader
    Pfizer May 1995 - Jan 2000
    New York, New York, Us
    Worked on CNS disorders, cardiovascular diseases, metabolic disorders, and urological diseases.
  • Pfizer
    Principal Scientist
    Pfizer Sep 1991 - May 1995
    New York, New York, Us
    Worked on CNS disorders, cardiovascular diseases, metabolic disorders, and urological diseases.
  • Wyeth-Ayerst
    Research Scientist
    Wyeth-Ayerst Sep 1988 - Aug 1991
    Worked on cardiovascular diseases, metabolic disorders, and urological diseases.
  • Ayerst Research
    Senior Scientist
    Ayerst Research Apr 1985 - Aug 1988
    Worked on aldose reductase inhibitors to treat diabetic complications.

John Butera Skills

Drug Discovery Medicinal Chemistry Drug Development Organic Synthesis Pharmaceutical Industry Adme Pharmaceutical Research Drug Design Clinical Development Biotechnology Parallel Synthesis High Throughput Screening Drug Metabolism Portfolio Management Women's Health Lead Finding Lead Optimization Cns Disorders Metabolic Disorders

John Butera Education Details

  • Rutgers University
    Rutgers University
    Mini-Mba Global Biopharma Entrepreneurship
  • Stony Brook University
    Stony Brook University
    Organic Chemistry
  • Dowling College
    Dowling College
    Chemistry

Frequently Asked Questions about John Butera

What company does John Butera work for?

John Butera works for Hager Biosciences, Llc

What is John Butera's role at the current company?

John Butera's current role is Chief Scientific Officer and Senior Vice President of Research.

What is John Butera's email address?

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What is John Butera's direct phone number?

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What schools did John Butera attend?

John Butera attended Rutgers University, Stony Brook University, Dowling College.

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John Butera has interest in Motorcycle Riding, Traveling, Reading, Music, Movies.

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John Butera has skills like Drug Discovery, Medicinal Chemistry, Drug Development, Organic Synthesis, Pharmaceutical Industry, Adme, Pharmaceutical Research, Drug Design, Clinical Development, Biotechnology, Parallel Synthesis, High Throughput Screening.

Who are John Butera's colleagues?

John Butera's colleagues are Lily Joshua.

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