Member of a protein engineering team supporting Intrexon's commercial divisions (Human Therapeutics, Industrial Products, Animal Science, and Agricultural Biotech) in development and analysis of proteins for both therapeutic and non-therapeutic potential. Played a lead role in the research, design, and analysis of proteins using in silico methods. • Co-inventor on 1 patent• In silico Antibody Engineering – scFv’s, scFv-Fc’s• In silico Chimeric Antigen Receptor Engineering• Generation of cytokines with novel pharmacokinetic properties as part of CRADA with NCI. Going into clinical trials• Generation of novel inhibitor molecules to treat wet AMD. Sun Pharma-XON joint venture. Going into clinical trials• Identification of broad neutralizing protein targets on the surface of a human viral pathogen• Identification of antigenic targets on the viral Capsid protein of a common animal pathogen• Identification of putative plant drought tolerance genes using phylogenetic analysis• Technical Skills: PyMol, Discovery Studio, homology modeling, in silico target validation, data mining• Project Management Skills: Generating timelines, Producing plans & estimates, Writing project proposals & charters• Project Management Skills: Risk identification, assurance of execution of deliverables and milestones for research programshttp://www.DNA.com

Member of an interdisciplinary team of 25 scientists developing the Conserved Domain Database (CDD) for protein classification and interactive protein domain family analysis. Primary contributor of thousands of structure-based, functionally-annotated multiple sequence alignment models to the CDD. My strengths include 3D protein structure superposition, homology modeling, sequence-structure analysis, functional site annotation/prediction, phylogenetic analysis, protein superfamily classification and scientific writing. Lead Scientist: Aron Marchler-Bauer, PhD• Creation of protein structure-based, functionally-annotated multiple sequence alignment models• Classification of protein superfamilies using phylogenetic analysis • Scientific Writing: Project Reports, Scientific Posters, Abstracts• Technical Skills: Cn3D, CDTree, MMDB, phylogenetic analysis, data mining• Co-author of 6 peer-reviewed publications.

Member of an interdisciplinary team of scientists developing the Clusters of Orthologous Groups of proteins (COGs) Database, an evolutionary classification of proteins from major phylogenetic lineages. Responsibilities included assigning proteins from several whole genomes to COGs and KOGs using sequence analysis and comparative genomics. • Co-author of 3 peer-reviewed publications.

Postdoctoral Research Fellow in the Skin Research Center at Johnson&Johnson Consumer Products Inc. Tested hundreds of natural products for their effect on skin pigmentation in laboratory mice, a number of which were chosen for further testing.

Cloned the gene encoding the Saccharomyces cerevisiae histone H2A.Z, deleted the gene in various yeast strains, and examined the phenotypic effects of the deletion. • Scientific writing: peer-reviewed publications, posters, abstracts, SOPs• Technical skills: PCR, DNA cloning, electroporation, phenotypic screening of mutations• Co-author of 2 peer-reviewed publications as first-author.

Cloned a large cis-regulatory element controlling beta-globin gene expression called the beta-LCR (Locus Control Region), and assayed for the functional role of beta-LCR subregions in transfected erythroleukemia cells. • Generation of stably transformed hematopoietic cell lines• Development of a novel soft agar assay for isolating stably expressing hematopoietic cell clones• Design and construction of a beta-globin-luciferase reporter gene expression vector• Scientific writing: peer-reviewed publications, posters, abstracts, SOPs• Technical skills: PCR, DNA cloning, electroporation, luciferase assays, expression assays• Instructor for undergraduate molecular biology laboratory classes• Co-author of 5 peer-reviewed publications (2 first-author) • Co-author of 2 book chapters (1 first-author).

Research Assistant in the Biochemistry Department at Boston University School of Medicine. Cloned procollagen alpha-2(I) promoter elements and studied the effect of promoter methylation on procollagen alpha-2(I) gene regulation in cultured cells.• Technical skills: PCR, DNA cloning, DNA sequencing, electroporation, expression assays• Co-author of 1 peer-reviewed publication.