Jonathan Ewald Phd Chrc Email & Phone Number

Boston, Massachusetts, United States

Leading the Research Compliance Center of Excellence within BILH system corporate Office of Integrity & Compliance. Managing relationships with adjacent stakeholder groups to provide guidance to Investigators and Research Ops. Providing oversight to all aspects of Basic, Translational and Clinical Research performed within the Beth Israel Lahey Health system and supporting our partners in Harvard Medical School.

Chillicothe, Ohio, United States

Building leadership in a Research Compliance function for a community health system serving a 9 county area in south-central Ohio.Providing regulatory oversight, administrative guidance and subject matter expertise to established and growing multi-departmental research programs within the Regional Medical Center and across the system. Partnering with physician investigators to develop relationships across academia and industry.Appointed Human Protections Administrator for the Institution.Appointed to Health Ethics Committee as a consultant. Supporting and strategizing the systematizing or HEC administration and operations. Serving as Research Compliance Officer.

Pro bono private advisory business and scientific consulting to friends in healthcare, tech, biotech, and pharma industries.

North Haven, Ct

Supporting development of local Graduate Medical Education/Medical Residence program at Mercy Medical Center/Trinity Health of New England.

Springfield, Massachusetts Area

De novo build of Department of Clinical Research at a critical access community hospital and integration into regional and national system resources. • Establishment of formal research program in Medical and Radiation Oncology, and outside practices. Program projected to retain 20-30 patients/year. • Singular local management of all aspects of research administration, operations and compliance. De facto local Research Integrity/Compliance Officer. Collaboration with local and regional Corporate Compliance personnel to establish Research Compliance standards. • Highly matrixed reporting responsibilities and collaboration in diverse leadership teams. • Public outreach, resulting in institutional Innovation Award for Medical Oncology and $90k donated to hospital foundation in 1 year. • Personnel management of Investigator, Research Nurse and Coordinator teams, providing training, development and mentorship. • Member of Mercy Medical Center Cancer Committee. Major contributor to obtaining/maintaining accreditation for Sr Caritas Cancer Center, Mercy Breast Care Center, Graduate Medical Education program • Program development and growth strategies to foster collaborative projects between Mercy and St Francis Hospital/Yale-Smilow Cancer Hospital, outside practices, industry sponsors, and others. • Charter member of THoNE Scientific Review Committee, and committee co-liaison to Institutional Review Board. Providing mentorship and support for production of manuscripts, proposals, and regulatory documents. • Technical scientific expertise supporting physicians and recruitment to studies for targeted therapeutics. • Development of formal administrative processes for feasibility reviews, coverage analyses, study budget development, contract negotiations and submissions. • Major contributor to development of Local and Regional/System-Wide policies, procedures and SOPs governing participation in clinical trials.

Hq In Vancouver, Wa; 10 Hospitals Across Alaska, Washington And Oregon

System resource actively contributing to operations and compliance of clinical research projects across a 10 hospital system. - Contribute to the centralization and systematization of research operations and compliance, with reporting responsibilities to VP Chief Medical Officer, VP Organizational Integrity, Operations, and Finance.- Engagement with researchers to assess potential and human subjects concerns of clinical research and quality improvement project proposals.- Support of Institutional Review Board functions. Service as alternate voting member. - Direct experience in areas of Human Subjects Protections, HIPAA privacy rules, Conflict of Interest, Scientific Integrity, pre- and post-award Grants Management (supporting A-133/Single Audit), Research Effort Reporting. - Member of PeaceHealth Scientific Misconduct Committee.- Policy and procedure development, maintenance, and management.- Performance of Compliance Risk Assessments and Audits.- Coordination and leadership of Grants & Sponsored Projects team. - Central contact, subject matter expert and resource for information and collaboration on issues impacting clinical research enterprise and individual projects.- Presentation of information to Organizational Integrity, executive teams, and other committees. - Collaboration with Marketing & Communications to produce quarterly educational newsletters and content for outreach.- Develop and foster relationships with diverse stakeholders across research enterprise.

Madison, Wisconsin

Administrative experience: Project leader in the development of cutting-edge basic/translational/clinical uro-oncology projects in two separate laboratories.- Leadership in the development, initiation, design and management of research projects.- Develop and foster relationships with collaborating laboratories.-Major contributor to grant proposals to NIH/NCI and DOD, including design of clinical research protocols.-Development, maintenance and management of internal and external regulatory submissions for human subjects, animal, chemical, and biological protocols. -Regular presentation of lectures to laboratory, collaborators, internal research groups, and at external meetings.-Mentorship and training to undergraduate, graduate and medical students, post-docs and technical staff. Technical Experience:Mined public expression microarray data to identify a 7 biomarker panel to differentiate superficial and muscle-invasive bladder tumors. Developed a method utilizing Excel to achieve this.-Described the systems level characterization of a novel model of human prostate cancer development and progression. -Investigated the relationship of EGFR and estrogen receptors in bladder cancer, prostate cancer, and benign prostate hyperplasia. -Developed and executed high throughput screens for drugs that induce senescence in prostate cancer cells.-Described mechanism of therapy-induced senescence in prostate cancer cells.-Characterized senescence-like response of prostate tumors to therapeutic androgen ablation.- Development of a high-throughput method to screen chemical libraries to identify senescence-inducing activity in drugs.-----Link to my papers in PubMedhttps://www.ncbi.nlm.nih.gov/sites/myncbi/10cqnK5fcsk/bibliography/41355881/public/?sort=date&direction=descending

Richland, Wa

Systems Biology of EGF Receptor Activity, Endocytic Processing, Ligand-Associated Responses

Nashville, Tn

Kinase-independent, ligand-independant pro-survival activities of the EGFR in cancer cells.

Phd, Molecular Biology

First to identify anti-apoptotic pro-survival activity of EGFR independent of ligand-activation and/or kinase activity. Developed superior.

Bs, Biology

Activities and Societies: Biology ClubMajor in Biology. Minor in Chemistry. Fulfilled all requirements for a 2nd minor in philosophy.