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Former drug discovery scientist passionate about building new biotech companies and developing innovative medicines to treat human disease
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Vice PresidentOrbimed Feb 2022 - PresentNew York, Ny, Us -
Senior AssociateOrbimed Mar 2020 - Feb 2022New York, Ny, Us -
PrincipalAccelerator Life Science Partners May 2017 - Mar 2020Seattle, Washington, Us-Lead and support all aspects of company building and operations including: deal sourcing, technical and business diligence, talent recruitment, contract negotiations, project management, budget oversight, corporate and business development, preparing and presenting board meeting materials -
AssociateAccelerator Life Science Partners Jul 2015 - May 2017Seattle, Washington, Us-Lead and support all aspects of company building including: deal sourcing, diligence, company operations-Company creation activities: Petra Pharma ($48M); Lodo Therapeutics ($17M); ApoGen, deal lead ($7M)-Source new deals by attending networking events, startup pitch competitions and conferences, relationship building with tech transfer officers and key faculty, scientific literature review-Perform diligence activities including: competitive landscape and market analyses, engaging KOLs, collaborating with pharma partners on diligence, building research plans and associated budgets and drafting investment memos-Support company operations including: sourcing key personnel, identifying and facilitating business development opportunities, project and CRO management, scientific oversight and preparing board meeting decks-Manage deal flow by logging and tracking all opportunities in a database, running weekly triage meetings, tracking action item progress by team; provide deal flow analytics to CEO for presentation to investors-Generate monthly dashboard updates of portfolio companies for CEO to share with board of directors -
Scientist ITakeda Oncology Sep 2013 - Jul 2015Cambridge, Ma, Us-Research scientific literature and current trends in oncology drug discovery and development to identify and propose novel drug targets to senior management-Collaborate with cross-functional team members, locally and globally, to develop experimental research plans and coordinate research activities in support of new target ideas-Summarize research and present findings at internal project team meetings to the senior management -Leading biology efforts for early-stage new target projects through validation towards go/no-go decision points-created "New Targets Working Group", aimed to bring together scientists working on new target projects in order to share ongoing project data, best practices and troubleshoot technical issues-Member of "Early Portfolio Group" tasked to propose, evaluate and prioritize new targets-Performing and managing triage, due diligence and legal activities associated with early-stage (preclinical through Phase I) business development opportunities, coordinating communications with external parties and attending face to face meetings with potential partners-Attend and contribute to roundtable discussions with invited academic speakers to discuss potential areas of collaboration-Scouting for new targets and technologies at scientific conferences -
Postdoctoral FellowTakeda Oncology May 2011 - Aug 2013Cambridge, Ma, UsInvestigating the role of autophagy in the pathogenesis and treatment of cancer. I am developing cell-based drug discovery tools for target validation and mechanism of action studies of a cancer metabolism target of interest within the autophagy pathway. I am additionally exploring potential biomarkers for predicting whether specific tumor subtypes are sensitive or resistant to autophagy inhibition. -
Postdoctoral FellowColumbia University Medical Center Nov 2010 - Mar 2011New York, New York, UsInvestigating the molecular and genetic pathogenesis of diffuse large B-cell lymphoma. Using a combination of genome-wide approaches, in vitro functional assays and in vivo mouse models, we are elucidating the role of recurrently mutated genes in the pathogenesis of DLBCL. -
Graduate Research AssistantColumbia University Medical Center Sep 2005 - Oct 2010New York, New York, UsInvestigating the molecular and genetic pathogenesis of diffuse large B-cell lymphoma. Using a combination of genome-wide approaches, in vitro functional assays and in vivo mouse models, we are elucidating the role of recurrently mutated genes in the pathogenesis of DLBCL.
Jonathan Mandelbaum Skills
Jonathan Mandelbaum Education Details
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Columbia UniversityMolecular And Biophysical Studies -
Mcgill UniversityBiology
Frequently Asked Questions about Jonathan Mandelbaum
What company does Jonathan Mandelbaum work for?
Jonathan Mandelbaum works for Orbimed
What is Jonathan Mandelbaum's role at the current company?
Jonathan Mandelbaum's current role is Healthcare Venture Capital at OrbiMed.
What is Jonathan Mandelbaum's email address?
Jonathan Mandelbaum's email address is jo****@****ail.com
What is Jonathan Mandelbaum's direct phone number?
Jonathan Mandelbaum's direct phone number is +151631*****
What schools did Jonathan Mandelbaum attend?
Jonathan Mandelbaum attended Columbia University, Mcgill University.
What skills is Jonathan Mandelbaum known for?
Jonathan Mandelbaum has skills like Molecular Biology, Drug Discovery, Biotechnology, Oncology, In Vivo, Life Sciences, Mouse Models, Cancer, Flow Cytometry, Immunofluorescence, Metabolism, Cell Culture.
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