Jonathan O'Connell Email and Phone Number
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Highly experienced Vice President with an outstanding track record in Early Discovery. Currently Head of Discovery Platform at Dewpoint Therapeutics, responsible for Platform Teams in Boston and Germany, as well as LabOps and Facilities at both locations. Established a team and infrastructure to enable the discovery and optimization of condensate modifying drugs (c-mods) using purely phenotypic assays, which has delivered two late-stage LO series and multiple early-stage molecules in a 2-year period.As a key leader at FORMA Therapeutics, I established a platform to enable delivery of seven clinical assets in seven years. As FORMA transitioned to a clinical organization, I drove the exploration and outreach for partnering opportunities for the Early Discovery Team which ultimately resulted in the acquisition of my team, infrastructure, libraries and a number of assets by Valo Health in 2020. I have twenty-eight years of experience in Big-Pharma and Biotech in preclinical drug discovery, and my career is distinguished with a proven ability to manage diverse teams, drive innovation, optimize operational processes and enhance scientific value. I am passionate about developing the next generation of scientific leaders and have been commended for cultivating an environment of innovation, teamwork and mentorship.
Takeda
View- Website:
- takeda.com
- Employees:
- 36992
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TakedaCambridge, Massachusetts, United States
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Head Of Discovery PlatformDewpoint Therapeutics Feb 2022 - PresentBoston, Ma, Us -
Vice President, Early Discovery & Technology At Valo HealthValo Health Mar 2020 - Feb 2022Lexington, Ma, UsGlobal industry-leading expert in hit identification and all associated fields from automated chemistry and compound management through HTS and DNA-encoded libraries (DEL), to assay design and lead optimization. Significant experience in leveraging and integrating AI and ML into all aspects of the preclinical drug discovery processStrategic leadership. Key member of a leadership team driving company strategy. Engaged in financial management, investor and partner relations and scientific directionActing head of biology at Valo. Broad accountability for Oncology, Neurodegenerative and Cadiovascular in partnership with other key leaders. Direct mentorship of the Biology team. Long term strategic planning covering target strategy, FTE, OpEx and CapEx investment to achieve corporate goalsOverall leadership for lab relocation and site head for new location. Identified new space, deigned and oversaw the build, move and commissioning of a 30,000sqft laboratory to accommodate a rapidly growing company Outstanding team player, driving interactions and creating an environment to get the best out of every individual. Consistently recognized for teamwork and communication. Currently managing teams across multiple sites -
Vice PresidentForma Therapeutics, Inc. 2018 - Mar 2020Watertown, Massachusetts, Us -
Executive Director And Head Of Early DiscoveryForma Therapeutics, Inc. May 2017 - Mar 2020Watertown, Massachusetts, UsAs VP of Early Discovery at FORMA Therapeutics in Watertown, MA I was responsible for the early portfolio from target selection to the delivery of targets with validated chemical matter into Hits to Leads. With a comprehensive understanding of early Drug Discovery, I was acting Head of Discovery, including Hematology/Oncology biology and medicinal chemistry at FORMA Therapeutics. I built a high capacity HTS team which performed both high throughput screens to identify new chemical matter, and ran key assays to drive SAR for Forma's pipeline. This team was a center for assay design for both biochemical and cellular assays covering the full range of assays typically required for advanced program progression from basic fluorescence, through kinetic analysis to high throughput RT-PCR and High Content Assays. Additionally, I was accountable for both developing and managing number of our external partnerships, leveraging external expertise to complement our internal capabilities.Specialties: Portfolio management, Leadership, Assay Design, Enzymology, ADME-Tox, Ion Channels, GPCRs, Technology & Automation, Innovation & Process Optimization.
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Head Of Early DiscoveryForma Therapeutics, Inc. Feb 2017 - Mar 2020Watertown, Massachusetts, Us
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Senior Director: Biomolecular ScreeningForma Therapeutics, Inc. Dec 2013 - Mar 2020Watertown, Massachusetts, UsDirector of the Biomolecular Screening Group at Forma Therapeutics
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DirectorBristol-Myers Squibb Mar 2000 - Dec 2013Lawrence Township, Nj, UsDirector of Lead Discovery & Lead Evaluation at Bristol-Myers Squibb where responsibilities included leadership of a number of teams: A centralized high-throughput screening facility, a Lead Optimization group for Neuroscience and Virology, a centralized team of ion channel specialists, an automation support team, a cellular resource team provided stable cell lines and continuous culture, and a centralized in vitro ADME team supporting programs across six therapeutic areas. -
Lead DiscoveryGlaxosmithkline 1996 - 2000Brentford, Middlesex, GbMember of the High Throughput Screening Group at GSK and was responsible for assay design and screening for enzyme-based targets..
Jonathan O'Connell Skills
Jonathan O'Connell Education Details
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University Of GlasgowBiochemistry -
The University Of ManchesterBiochemistry & Molecular Biology
Frequently Asked Questions about Jonathan O'Connell
What company does Jonathan O'Connell work for?
Jonathan O'Connell works for Takeda
What is Jonathan O'Connell's role at the current company?
Jonathan O'Connell's current role is Head of Discovery Platform at Dewpoint Therapeutics.
What is Jonathan O'Connell's email address?
Jonathan O'Connell's email address is jo****@****ics.com
What is Jonathan O'Connell's direct phone number?
Jonathan O'Connell's direct phone number is (203)-677*****
What schools did Jonathan O'Connell attend?
Jonathan O'Connell attended University Of Glasgow, The University Of Manchester.
What skills is Jonathan O'Connell known for?
Jonathan O'Connell has skills like Drug Discovery, High Throughput Screening, Assay Development, Pharmaceutical Industry, Biochemistry, Biotechnology, Laboratory Automation, Life Sciences, Drug Development, Research, Gpcrs, Molecular Biology.
Who are Jonathan O'Connell's colleagues?
Jonathan O'Connell's colleagues are John O'brien, Sean Ganley, Valerie Anderson, Alexandra Gonzalez, Tina B., Adrielle Amaro, Mahmoud F. Moussa.
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