Jonathan Thon, Ph.D. Email & Phone Number

Cambridge, Ma, Us

Cheshire, England, United Kingdom

Ma, Us

Octagon Therapeutics is a venture-backed company developing Ab-based immunomodulatory therapies for severe autoimmune disease.Recruited with charter to represent the Common stockholders and inform corporate governance, business, research and regulatory strategy, organizational structure, evaluate executive performance, and fulfill fiduciary responsibilities.• Supporting CEO in directing company through drug candidate selection and follow-on financing.

Cambridge, Ma, Us

Acoustica Bio is a venture-backed company developing highly concentrated biologic formulations for subcutaneous delivery.Recruited with charter to provide strategic advice and inform corporate strategy, stakeholder alignment, platform development and mission, organizational structure, and financing strategy.• Supporting CEO in developing company through initial partnerships and corporate growth.

New Haven, Ct, Us

Early sounding board, advisory, and operational support for Yale faculty and students commercializing research discoveries into viable startup companies.

mDETECT is a privately held liquid biopsy company for the early detection and management of various cancers. Responsible for providing strategic advice and network support for business development, partnership, and financing.

Boston, Ma, Us

STRM.BIO is a venture-backed privately held nonviral gene delivery platform company in rare blood diseases.

Boston, Ma, Us

Founded and led startup to develop first gene delivery platform capable of completely bypassing the liver to target long-term hematopoietic stem cells in vivo. Hired as founding CEO with charter to raise venture funding and establish pre-clinical research and development program.• Recruited executive team, board of directors, and scientific advisory board.• Raised more than $42M in venture financing and non-dilutive grants incl. the Bill & Melinda Gates Foundation, and the National Institutes of Health, and ARPA-H.• Grew company from startup to ~20 employees.• Established and scaled a cell culture manufacturing process.• Invented, established, and grew broad IP portfolio. Negotiated options/licenses.• Led regulatory strategy and oversaw CATT and INTERACT engagements with the FDA.

ForCell is a privately held microfluidic-based gene loading company for the cell therapy and antibiotics resistance markets.Responsible for providing strategic advice and network support for company ideation, formation, and financing.

Watertown, Ma, Us

Stellular Bio (formerly Platelet BioGenesis) is a venture-backed privately held cell therapy company in hematology.

Watertown, Ma, Us

Watertown, Ma, Us

Co-founded and led startup with intellectual property portfolio licensed from Harvard University to produce the first functional human platelets from iPSC culture to treat hematological and oncological diseases. Hired as founding CEO with charter to raise venture funding and establish pre-clinical research and development program.• Recruited executive team, board of directors, and scientific advisory board.• Raised more than $100M in two rounds of venture financing and non-dilutive grants incl. the Department of Defense, the National Institutes of Health, and BARDA.• Grew company from startup to 40+ employees.• Established and scaled a cell culture manufacturing process.• Invented, established, and grew broad IP portfolio. Negotiated options/licenses.• Led regulatory strategy and oversaw Pre-IND engagement with the FDA.

Ichosia is a privately held red blood cell substitute company in hematology.Responsible for providing scientific advice and strategic support for company ideation, technology development and validation.

Optiva Fertility is a venture-backed privately held tech/bio company in reproductive medicine.Recruited with charter to oversee and inform corporate governance, business and intellectual property strategy, company policies, evaluate executive performance, and fulfill fiduciary responsibilities.• Supported first-time CEO in directing company through pivotal clinical study.• Negotiated company wind-down following negative clinical readout.

Entrepreneur-in-residence, instructor.Help inventors at Harvard and associated institutions translate cutting-edge technology through entrepreneurship.

Cell culture and microfluidics academic research lab in hematology & oncology. By combining novel concepts in bone marrow and pulmonary physiology with advanced tissue engineering, my lab developed a patented, cGMP-compliant, scalable platelet bioreactor with the potential to replace to donated platelets for transfusion to cancer and trauma patients. My work led to the identification of previously unknown intermediate stages in the production of platelets; the physiological and chemical triggers of platelet production; and the development of a human platelet bioreactor.• Raised more than $7.1M in partnerships and grants.• Published >30 peer-reviewed manuscripts, >20 as first/corresponding author.• Guided dozens of students toward rewarding careers in medicine and biopharma.

Developed bio-mimetic microfluidic platforms to generate functional platelets and new targeted therapies for thrombocytopenia.

Science consultant for the entertainment industry.

Postdoctoral Research Fellowship, Hematology

Doctor Of Philosophy (Ph.D.), Biochemistry And Molecular Biology

Honors Bachelors Of Science, Biotechnology And Genetic Engineering

Entrepreneurship/Entrepreneurial Studies

Incubator, Entrepreneurship/Entrepreneurial Studies

Incubator, Entrepreneurship/Entrepreneurial Studies

Incubator, Harvard Innovation Lab

Certificate, Healthcare Innovation And Commercialization

Certificate, Design And Conduct Of Clinical Trials

Certificate, Analytical And Quantitative Light Microscopy